Results 311 to 320 of about 1,522,500 (352)
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Single nucleotide polymorphisms in breast cancer
Oncology Reports, 2004A limited number of genes have been identified that explain heritable risks of breast cancer (BC). We searched for low-penetrant genes in an association study using two populations: 223 Finnish unselected patients and 172 Polish familial cases, both with locally collected healthy controls.
Ewa Grzybowska +12 more
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Single Nucleotide Polymorphisms and Pharmacogenomics
2021Pharmaco-genomics determines the individual genetic mechanism for drug response and has the ability to transform tailored medication into clinical practice. A huge number of individuals die every year from adverse drug response since each person reacts differently to similar drug.
Sabhiya Majid +9 more
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Cytokine Single Nucleotide Polymorphisms in Iran
Journal of Interferon & Cytokine Research, 2006Overall expression and secretion of cytokines are dependent on genetic nucleotide variations within or adjacent to regulatory regions of cytokine genes. This study allows the comparison of the prevalence of particular genetic markers. In 40 Iranian healthy subjects, cytokine single nucleotide polymorphisms (SNPs) were used to determine allelic and ...
Davood Omrani +2 more
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Single nucleotide polymorphisms: aging and diseases
Biogerontology, 2004Differences of more than 3 million nucleotides can bee seen comparing the genomes of two individuals as a result of single nucleotide polymorphism (SNP). More and more SNPs can be identified and it seems that these alterations are behind of several biological phenomena.
Margit Zeher +4 more
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Genotyping of Single Nucleotide Polymorphisms
2015Single nucleotide polymorphisms (SNPs) are the most abundant DNA variations in human genome. Numerous reports have indicated that SNPs are closely associated with diseases such as cardiovascular diseases, different types of cancer, and other genetic diseases.
Tian Ye, Ran Tong, Zhiqiang Gao
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Single-Nucleotide Polymorphism Analysis by Pyrosequencing
Analytical Biochemistry, 2000There is a growing demand for high-throughput methods for analysis of single-nucleotide polymorphic (SNP) positions. Here, we have evaluated a novel sequencing approach, pyrosequencing, for such purposes. Pyrosequencing is a sequencing-by-synthesis method in which a cascade of enzymatic reactions yields detectable light, which is proportional to ...
Baback Gharizadeh +6 more
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Single Nucleotide Polymorphisms and Their Applications
2007SNPs are highly abundant in the human genome, explaining most of sequence variation. This makes them a valuable resource for population genetics, evolution, and gene mapping. In this article we have given an overview of the major issues arising in their application to haplotype and haplotype block estimation and genetic association.
Zhaoxia Yu, Rudy Guerra
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Shares in single nucleotide polymorphisms
Expert Opinion on Therapeutic Patents, 1999The announcement of a consortium between the public and private sectors to produce a public single nucleotide polymorphism (SNP) map of the human genome is a unique development which acknowledges the need for research tools to be widely available. The human genome project has been characterised by public-private tensions over information access and ...
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Single Nucleotide Polymorphism Typing
2019Single nucleotide polymorphism (SNP) typing process utilizes biochemical techniques to determine the sequential order of nucleotide bases in a DNA strand using sequencing machines. Last decade has witnessed a tremendous expansion since the invention of the Sanger sequencing.
Srinivasan, Srilakshmi, Batra, Jyotsna
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