Results 161 to 170 of about 479,118 (340)

Analysis of HorseMyostatinGene and Identification of Single Nucleotide Polymorphisms in Breeds of Different Morphological Types [PDF]

open access: hybrid, 2010
Stefania Dall’Olio   +5 more
openalex   +1 more source

Association of single nucleotide polymorphism in leptin gene with growth traits of Jamunapari goat

open access: diamond, 2021
Mahesh Shivananad Dige   +6 more
openalex   +2 more sources

Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Have Distinct Prediagnostic Blood Biochemical Profiles

open access: yesAnnals of Neurology, EarlyView.
Objective Identifying modifiable factors influencing amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) risk is important for prevention. Blood biomarkers, particularly cholesterol, have been associated with neurodegenerative risk, but findings in ALS are inconsistent, and data on FTD are limited.
Christos V. Chalitsios   +5 more
wiley   +1 more source

Comparative Effectiveness of Abatacept Versus Adalimumab in Shared Epitope Positive and Negative Patients With Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective The effect of the shared epitope (SE) and valine at position 11 (Val11) of HLA–DRB1 on the activation of CD4+ T cells is expected to be diminished by abatacept, a costimulation blocker. However, published evidence on the value of genetic stratification for abatacept treatment is conflicting. We aimed to compare the difference in effectiveness
Chuan Fu Yap   +14 more
wiley   +1 more source

Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease

open access: yesArthritis &Rheumatology, EarlyView.
Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman   +2 more
wiley   +1 more source

Transition from psoriasis to psoriatic arthritis is characterized by distinct alterations in peripheral blood Tc17, Th17 and CD4+ TEM cells

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Cellular mechanisms driving transition from psoriasis to psoriatic arthritis have remained largely elusive. Thus, we investigated changes within the peripheral blood T cell compartment associated with the transition phase. Methods In an observational study, 116 patients were examined and categorized into subgroups including psoriasis with at ...
Hanna Graßhoff   +19 more
wiley   +1 more source

Effect of time to start of biologic therapy on treatment response in childhood arthritis: Results from the UCAN CAN‐DU study

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To estimate the effect of time from symptom onset to start of biologic treatment on achieving inactive arthritis within six months in a cohort of juvenile idiopathic arthritis (JIA) patients. Methods The international UCAN CAN‐DU study prospectively enrolls JIA patients across Canada and the Netherlands.
Jelleke B. de Jonge   +102 more
wiley   +1 more source

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