Results 171 to 180 of about 263,691 (312)

L-RCA (ligation-rolling circle amplification): a general method for genotyping of single nucleotide polymorphisms (SNPs) [PDF]

, 2001
Xiaoquan Qi
openalex   +1 more source

Comparative Effectiveness of Abatacept versus Adalimumab in Shared Epitope positive and negative Rheumatoid Arthritis patients

Arthritis &Rheumatology, Accepted Article.
Objectives The effect of the shared epitope (SE), and valine at position 11 (Val11) of HLA‐DRB1, on the activation of CD4+ T cells, is expected to be diminished by abatacept, a co‐stimulation blocker. However, published evidence on the value of genetic stratification for abatacept treatment is conflicting.
Chuan Fu Yap, Nisha Nair, Seema D Sharma, John Bowes, Amirah Binti Mohammad Ariff, Ann W Morgan, John D Isaacs, Anthony G Wilson, Kimme L Hyrich, Suzan Verstappen, James Bluett, Andrew P Morris, Anne Barton, Darren Plant, Sebastien Viatte   +14 more
wiley   +1 more source

The human XPG gene: gene architecture, alternative splicing and single nucleotide polymorphisms [PDF]

, 2001
Steffen Emmert
openalex   +1 more source

The tacrolimus concentration‐to‐dose ratio is associated with kidney function in heart transplant recipients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Heart transplantation (HT) is frequently complicated by chronic kidney disease, of which tacrolimus‐related nephrotoxicity is an important cause. In kidney and liver transplant recipients, fast tacrolimus metabolism (defined as a low concentration‐to‐dose [C0/D] ratio), negatively affects kidney function.
Maaike R. Schagen, Teun B. Petersen, Boris C. A. Seijkens, Jasper J. Brugts, Kadir Caliskan, Alina A. Constantinescu, Brenda C. M. de Winter, Isabella Kardys, Dennis A. Hesselink, Olivier Manintveld   +9 more
wiley   +1 more source

Genetic Diversity and Conservation Priority of Korean Chicken Breeds Using Single-Nucleotide Polymorphism Markers. [PDF]

Animals (Basel)
Song H, Kim Y, Lee S, Choi B, Kim S, Jin D, Kim G, Ha S, Mun S, Cho Y, Chung Y.   +10 more
europepmc   +1 more source

Novel single nucleotide polymorphisms (SNPs) at positions 497 (T/G) and 829 (T/C) in the human c-FOS gene and haplotype association Communicated by: Mark H. Paalman Online Citation: Human Mutation, Mutation and Polymorphism Report #156 (2000) Online http://journals.wiley.com/1059-7794/pdf/mutation/mpr156.pdf Acknowledgments: We would like thank Dr. J. Ohashi for his helpful discussion. This work was supported by Grants-in-Aid from the Ministry of Education, Science, Sports and Culture of Japan.

, 2000
Yumiko Umino, Hirohiko Hohjoh, Katsushi Tokunaga   +2 more
openalex   +1 more source

Flexible Use of High-Density Oligonucleotide Arrays for Single-Nucleotide Polymorphism Discovery and Validation [PDF]

, 2001
Shoulian Dong, Eugene Wang, Linda Hsie, Yanxiang Cao, Xiaogiong Chen, T Gingeras   +5 more
openalex   +1 more source

Cattle Genomics: Aurochs Admixture in East Asia

Animal Research and One Health, EarlyView.
James A. Ward, David E. MacHugh
wiley   +1 more source

Genetic causal association between heart failure, frailty and poisoning by narcotics and psychodysleptics: A two‐sample Mendelian randomization

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Observational studies have suggested associations between heart failure (HF), frailty and poisoning by narcotics and psychodysleptics (PNP). However, establishing causal relationships has been challenging. This study used a two‐sample Mendelian randomization (MR) approach to investigate the genetically proxied causality between HF ...
Bing Wang, Hong Yu, Meng Cai, Xianqiao Xie   +3 more
wiley   +1 more source

Feature Selection for Hypertension Risk Prediction Using XGBoost on Single Nucleotide Polymorphism Data. [PDF]

Healthc Inform Res
Muflikhah L, Fatyanosa TN, Widodo N, Perdana RS, Solimun, Ratnawati H.   +5 more
europepmc   +1 more source