Understanding pre‐eclampsia and fetal growth restriction at high altitude: A narrative review
Abstract Pre‐eclampsia (PE) and fetal growth restriction (FGR) are among the leading causes of maternal and perinatal morbidity and mortality worldwide. Both conditions are more frequent and severe at high altitudes due to physiological changes in oxygen availability and vascular adaptation.
Víctor S. Rangel +6 more
wiley +1 more source
A <i>POLR1D</i>-regulating single-nucleotide polymorphism as a predictive marker candidate for platinum-based chemotherapy in gastrointestinal cancers. [PDF]
Mori T +4 more
europepmc +1 more source
Abstract Objective Potential associations between reproductive traits and cognitive function have been discovered; however, the results are inconsistent, and the causalities are unclear. This study utilized Mendelian randomization (MR) analysis to assess the causal impact of reproductive traits on cognitive function.
Xia Wang, Yunyun Guo
wiley +1 more source
Analysis of ABCG2 gene rs2231142 single nucleotide polymorphism and risk factors in hyperuricemia. [PDF]
Liang M +10 more
europepmc +1 more source
Climate factors drive the local adaptation of Old World cattle
Climate adaptation genomics of cattle. We comparatively analyzed genomic data from 85 Old World cattle breeds/populations of Eurasia and Africa to identify genetic factors associated with climate factors. Environmental genome‐wide association studies revealed 3165 single‐nucleotide polymorphisms (SNPs) with strong correlations between climate factors ...
Luyang Sun +32 more
wiley +1 more source
A single nucleotide polymorphism in the <i>TCL1A</i> promoter is not protective in patients with germ line <i>RUNX1</i>-FPD. [PDF]
Kajdic A +11 more
europepmc +1 more source
Microbial metabolites in tumor epigenetic regulation
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang +31 more
wiley +1 more source
Discovery and development of single-nucleotide polymorphism markers for resistance to <i>Striga gesnerioides</i> in cowpea (<i>Vigna unguiculata</i>). [PDF]
Ongom PO, Fatokun CA, Boukar O.
europepmc +1 more source
ABSTRACT Psoriasis is a chronic autoimmune disease characterized by systemic inflammation and skin involvement, affecting millions of individuals worldwide. However, few studies have evaluated whether psoriasis and cardiac magnetic resonance imaging (CMR) traits share a common genetic basis.
Junlin Yang +8 more
wiley +1 more source
A retrospective single center analysis of fetuses with region of homozygosity detected by single nucleotide polymorphism array. [PDF]
Bu X +8 more
europepmc +1 more source

