Results 91 to 100 of about 5,755,630 (299)

Aggregation of Single Nucleotide Polymorphisms in a Human H5N1 Clade 2.2 Hemagglutinin [PDF]

, 2007
The evolution of H5N1 has attracted significant interest 1-4 due to linkages with avian 5,6 and human infections 7,8. The basic tenets of influenza genetics 9 attribute genetic drift to replication errors caused by a polymerase complex that lacks a ...
Moustafa M. Mansour, William K. Ampofo, Mona M. Aly, Mensah Agyen-Frempong, Ahmed S. Abdelghani, Nasr El-Sayed, Jeffery Tjaden, Magdi D. Saad, Ehab A. Ayoub, Abdelattar Arafa, Kenneth C. Earhart, Emad M. Labib, Hala M. Esmat, Gregory A. Raczniak, Bruce R. Boynton, Henry L. Niman, Ahmed E. Nayel, Marshall R. Monteville   +17 more
core  

Single nucleotide polymorphisms (SNPs) unique to high virulence isolates.

, 2015
Single nucleotide polymorphisms (SNPs) unique to high virulence isolates.
Rebecca E. Colman (254707), Apichai Tuanyok (78029), Christopher J. Allender (189556), James M. Schupp (193214), Katy J. Califf (710313), Bart J. Currie (131288), H. Carl Gelhaus (710315), Paul Keim (69765), Jason W. Sahl (276694), Kristopher E. Van Zandt (710314)   +9 more
core   +1 more source

Transposable Element Dynamics Drive the Genomic Evolution and Phenotypic Diversification of Allotetraploid Common Carp

Advanced Science, EarlyView.
By integrating 516 whole‐genome resequencing datasets and 236 transcriptomes of allotetraploid common carp, this study establishes the first population‐scale atlas of transposable element (TE) variation in teleost species. TE bursts, relaxed purifying selection, and lineage‐specific loss of ancient insertions shape genome evolution and phenotypic ...
Shuimu Hu, Zhou Jiang, Lin Chen, Gowena Ling Yi Goh, Weijing Li, Qian He, Xintong Chen, Rui Li, Yuxuan Liu, Ning Li, Tao Zhou, Peng Xu   +11 more
wiley   +1 more source

Association of Single Nucleotide Polymorphisms in Nucleotide-Binding Domain Leucine-Rich Repeat Protein 1 with Clostridioides difficile Colonization or Infection

Infection and Drug Resistance, 2023
Bo-Yang Tsai,1,* Pei-Jane Tsai,1– 4,* Ching-Chi Lee,5,6 Chun-Wei Chiu,7 Yi-Hsin Lai,4 Jen-Chieh Lee,6 Wen-Chien Ko,6,8 Yuan-Pin Hung6– 9 1Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan ...
Tsai BY, Tsai PJ, Lee CC, Chiu CW, Lai YH, Lee JC, Ko WC, Hung YP   +7 more
doaj  

Single nucleotide polymorphisms in E. gingivalis isolates.

, 2013
Single nucleotide polymorphisms in E. gingivalis isolates.
Gabriel A. N. Nascentes (500510), Túlio T. Richinho (500508), Kennio Ferreira-Paim (500507), Dalmo Correia (354864), Eliane Lages-Silva (500512), Sibeli B. S. Cembranelli (500505), Fernanda O. Souto (500506), Poliana L. Nunes (500509), Thatiana B. Ferreira (500511)   +8 more
core   +1 more source

Dual Repression by IPA1 Fine‐Tunes OsbZIP79‐Mediated Salt Tolerance in Rice

Advanced Science, EarlyView.
Dual repression by IPA1 fine‐tunes OsbZIP79‐mediated salt tolerance in rice: direct transcriptional inhibition under normal conditions and salt‐induced degradation under stress. This dual mechanism activates OsbZIP79 to regulate Na+/K+ homeostasis and redox balance via downstream genes, enabling optimal salt stress response.
Hui Wang, Bo Liu, Can Hu, Chenfan Zheng, Yuting Wei, Xier Xu, Wei Yang, Yu Fang, Guangle Shen, Pedro García‐Caparros, Conghe Zhang, Qingyao Shu, Meng Jiang   +12 more
wiley   +1 more source

Details of single nucleotide polymorphisms related to metformin.

Details of single nucleotide polymorphisms related to metformin.
Mingzhu Chen (6370013), Shuisen Lin (18120958), Xiaoqiang Chen (214695), Wanqiong Chen (18120961)   +3 more
core   +1 more source

Post-genomic structural analysis of single amino acid polymorphisms [PDF]

, 2009
Inherited genetic variation is critical in defining disease susceptibility. PDs, or pathogenic deviations, are mutations reported to be disease-causing, while SNPs, or single nucleotide polymorphisms, are understood to have a negligible effect on ...
McMillan, L.E.M.
core  

Number of single nucleotide polymorphisms differences between each strain.

, 2014
Number of single nucleotide polymorphisms differences between each strain.
Shannon D. Manning (148732), Ray T. Cursons (533378), Emily Marchiano (533383), David Alland (31640), Noel Karalus (533380), Vic L. Arcus (533377), Roberto Colangeli (31628), Soyeon Kim (533382), Ali Ruthe (533379), Kathy Coley (533381)   +9 more
core   +1 more source

WFS1 Deficiency Impairs PIAS4‐Associated SUMOylation and Increases Ubiquitin‐Mediated Spermatogenesis‐Related Protein Degradation Leading to Testicular Male Infertility

Advanced Science, EarlyView.
The findings establish a critical role for WFS1 in human male fertility. Mechanistically, WFS1 interacts with PIAS4 to promote the SUMOylation of key spermatogenesis‐associated proteins, which in turn competitively inhibits their K48‐linked ubiquitin‐mediated degradation during spermatogenesis.
Yunchuan Tian, Guicheng Zhao, Xiang Wang, Xinyao Tang, Gan Shen, Tiechao Ruan, Chuan Jiang, Shikun Zhao, Jincheng Zhang, Xinyue Cui, Liangchai Zhuo, Jun Ma, Yihong Yang, Tingting Lin, Ying Shen   +14 more
wiley   +1 more source