Results 1 to 10 of about 527,601 (289)

Predicting cell types and genetic variations contributing to disease by combining GWAS and epigenetic data [PDF]

, 2013
Genome-wide association studies (GWASs) identify single nucleotide polymorphisms (SNPs) that are enriched in individuals suffering from a given disease. Most disease-associated SNPs fall into non-coding regions, so that it is not straightforward to infer
A Milosavljevic, A Pekowska, A Visel, AJ Saldanha, AM Mondul, Anjana Rao, Anna Gerasimova, AR Quinlan, BE Bernstein, BE Himes, BE Stranger, Bin Li, Bjoern Peters, C Ober, C Zang, Consortium The International HapMap, D Karolchik, DB Hancock, DG Torgerson, E Birney, E Noguchi, EK Miller, F Castro-Giner, G Hon, GE Zentner, Gregory Seumois, J Ernst, J Ernst, J Harrow, Jason Greenbaum, JH Kim, JJ Farrell, KM Ansel, LD Ward, Lukas Chavez, MA Schaub, MF Moffatt, MF Moffatt, MJ de Hoon, MP Creyghton, MT Maurano, ND Heintzman, NU Rashid, Pandurangan Vijayanand, PB Talbert, PM Sleiman, PM Visscher, R Bhandare, R Jaenisch, S Chanock, S Michel, S Weidinger, T Hirota, TH Pham, W Yu, Y Li, Y Zhang, Yi-Hsiang Hsu   +57 more
core   +16 more sources

Genetic Analysis of The Leptin Gene in Goats Based on GenBank DNA Sequences

Jurnal Medik Veteriner, 2023
The Leptin gene is the gene that produces the leptin hormone, which is released from adipose tissue and can increase the productivity of animals. This study aimed to identify polymorphic nucleotides, changes in amino acid components, and species of goats
Muhammad Fajar Amrullah, Budi Utomo, Suzanita Utama, Tri Wahyu Suprayogi, Tita Damayanti Lestari, Tjuk Imam Restiadi, Ristaqul Husna Belgania   +6 more
doaj   +1 more source

Molecular genetic analysis of Yersinia pestis strains isolated in diff erent epizootic periods on the territory of the Ural-Embensky desert natural plague focus area in the twentieth century [PDF]

Известия Саратовского университета. Новая серия: Серия Химия. Биология. Экология, 2023
We performed a molecular genetic analysis of Yersinia pestis strains isolated in the Ural-Embensky desert natural plague focus area in the twentieth century. We studied 24 strains of Y.
Kovrizhnikov, Ekaterina V., Balykova, Alina N., Kukleva, Lyubov M., Naryshkina, Ekaterina A., Fedorov, Andrey V., Chervyakova, Nadezhda S., Eroshenko, Galina A., Kutyrev, Vladimir V.   +7 more
doaj   +1 more source

Genome-Wide association analysis of phenotypic traits in Bambara groundnut under drought-stressed and non-stressed conditions based on DArTseq SNP

Frontiers in Plant Science, 2023
IntroductionBambara groundnut (BG) (Vigna subterranea [L.] Verdc) is an indigenous, resilient, but underutilized leguminous crop that occurs mostly as genetically heterogeneous landraces with limited information on the drought tolerant attributes.
Kafilat Abiodun Odesola, Kafilat Abiodun Odesola, Kafilat Abiodun Odesola, Odunayo Joseph Olawuyi, Rajneesh Paliwal, Olaniyi Ajewole Oyatomi, Michael T. Abberton   +6 more
doaj   +1 more source

The association of vascular endothelial growth factor related SNPs and circulating iron levels might depend on body mass index

Frontiers in Bioscience-Landmark, 2022
Background and objectives: Vascular Endothelial Growth Factor (VEGF) is an essential regulator of vascular biology. In addition to the well-established role in angiogenesis, circulating VEGF levels were found elevated in severely anemic patients ...
Pia Chedid, Ali Salami, Mariam Ibrahim, Sophie Visvikis-Siest, Said El Shamieh   +4 more
doaj   +1 more source

Genome analysis in five Italian beef cattle breeds [PDF]

Acta Fytotechnica et Zootechnica, 2020
Chianina, Marchigiana, Maremmana, Podolica and Romagnola are the main Italian beef cattle breeds, and the quality of their products is largely recognized worldwide.
Giacomo Rovelli
doaj   +1 more source

Long cryopreserved lab-adapted Plasmodium falciparum increases resistance to chloroquine but not its susceptibility

Life Sciences, Medicine and Biomedicine, 2020
Introduction: Plasmodium falciparum (P. falciparum) is a deadly protozoan that is accountable for malaria and chloroquine was the first-line antimalarial drug before its withdrawal and replaced by artemisinin.
Jing Yit Pua, Nurhidanatasha Abu Bakar, Nik Abdul Aziz Nik Kamarudin, Siti Zulaiha Ghazali, Khairul Mohd Fadzli Mustaffa   +4 more
doaj   +1 more source

Genetic Polymorphism of Toll-Like Receptor 4 Thr399Ile Variant in Iraqi Kurdish Population: Sulaymaniyah Province

Passer Journal, 2020
Toll-like receptors (TLRs), encoded by innate immune genes, functions to detect microbial ligands. Studies found that polymorphisms in TLR genes among populations are associated with diseases.
Sherko S Niranji
doaj   +1 more source

Identification of genome diversity in Lari chicken using whole genome sequencing method [PDF]

مجله بیوتکنولوژی کشاورزی, 2021
Objective Evaluation and conservation of native chickensas valuable genomic resources is essential.This is the first study for discovering variants in Lari chicken by whole genome sequencing data. The study of genetic diversity of Lari chicken at genomic
Hamideh Bazgir, Ali Esmaeelizadeh, Zeynab Amiri, Masoud Asadi Fouzi   +3 more
doaj   +1 more source

Evaluation of the Role of Two SNPs in MTHFR Gene Polymorphisms (rs1801133) 677 C>T and (rs 1801131) 1298A>C with Homocysteine Level in Iraqi Patients with Chronic Kidney Disease [PDF]

Modern Medicine
Objectives: Objectives: The current study was designed to evaluate the role of MTHFR gene (rs1801133 and rs1801131) polymorphisms and investigate the serum Homocysteine level in Iraqi patients with CKD.
Saife AL-AHMER, Basima AL-SAADI, Ali AL SAEDI   +2 more
doaj   +1 more source