Results 21 to 30 of about 527,601 (289)

Germline genetic variation in prostate susceptibility does not predict outcomes in the chemoprevention trials PCPT and SELECT [PDF]

, 2020
Background The development of prostate cancer can be influenced by genetic and environmental factors. Numerous germline SNPs influence prostate cancer susceptibility.
Ahmed, M, Cieza-Borrella, C, Eeles, R, Goh, C, Kote-Jarai, Z, PRACTICAL consortium, Saunders, E, Schumacher, FR   +7 more
core   +2 more sources

SNP Arrays [PDF]

Microarrays, 2016
The papers published in this Special Issue “SNP arrays” (Single Nucleotide Polymorphism Arrays) focus on several perspectives associated with arrays of this type. The range of papers vary from a case report to reviews, thereby targeting wider audiences working in this field. The research focus of SNP arrays is often human cancers but this Issue expands
openaire   +2 more sources

DNA methylation and single nucleotide variants in the brain-derived neurotrophic factor (BDNF) and oxytocin receptor (OXTR) genes are associated with anxiety/depression in older women

Frontiers in Genetics, 2015
Background: Environmental effects and personal experiences could be expressed in individuals through epigenetic non-structural changes such as DNA methylation. This methylation could up- regulate or down-regulate corresponding gene expressions and modify
Yvon eChagnon, Olivier ePotvin, Carol eHudon, Michel ePreville   +3 more
doaj   +1 more source

Joint analysis of SNP and gene expression data in genetic association studies of complex diseases [PDF]

, 2014
Genetic association studies have been a popular approach for assessing the association between common Single Nucleotide Polymorphisms (SNPs) and complex diseases.
Huang, Yen-Tsung, Lin, Xihong, VanderWeele, Tyler J.   +2 more
core   +1 more source

SNP interaction pattern identifier (SIPI): an intensive search for SNP–SNP interaction patterns [PDF]

Bioinformatics, 2016
Abstract Motivation Testing SNP–SNP interactions is considered as a key for overcoming bottlenecks of genetic association studies. However, related statistical methods for testing SNP–SNP interactions are underdeveloped.
Lin, Hui-Yi, Chen, Dung-Tsa, Huang, Po-Yu, Liu, Yung-Hsin, Ochoa, Augusto, Zabaleta, Jovanny, Mercante, Donald E, Fang, Zhide, Sellers, Thomas A, Pow-Sang, Julio M, Cheng, Chia-Ho, Eeles, Rosalind, Easton, Doug, Kote-Jarai, Zsofia, Amin Al Olama, Ali, Benlloch, Sara, Muir, Kenneth, Giles, Graham G, Wiklund, Fredrik, Gronberg, Henrik, Haiman, Christopher A, Schleutker, Johanna, Nordestgaard, Børge G, Travis, Ruth C, Hamdy, Freddie, Pashayan, Nora, Khaw, Kay-Tee, Stanford, Janet L, Blot, William J, Thibodeau, Stephen N, Maier, Christiane, Kibel, Adam S, Cybulski, Cezary, Cannon-Albright, Lisa, Brenner, Hermann, Kaneva, Radka, Batra, Jyotsna, Teixeira, Manuel R, Pandha, Hardev, Lu, Yong-Jie, PRACTICAL Consortium, Park, Jong Y   +41 more
openaire   +6 more sources

Single nucleotide polymorphisms from Theobroma cacao expressed sequence tags associated with witches' broom disease in cacao [PDF]

, 2009
In order to increase the efficiency of cacao tree resistance to witches¿ broom disease, which is caused by Moniliophthora perniciosa (Tricholomataceae), we looked for molecular markers that could help in the selection of resistant cacao genotypes.
Carels, Nicolas, Cascardo, Julio Cezar M., Gaiotto, Fernanda Amato, Gesteira, Abelmon, Gramacho, Karina Peres, Lima, Leila S., Lopes, Uilson Vanderlei, Micheli, Fabienne, Novais, R., Pires, José Luis, Zaidan, Humberto A.   +10 more
core   +1 more source

ErbB polymorphisms: Insights and implications for response to targeted cancer therapeutics

Frontiers in Genetics, 2015
Advances in high-throughput genomic-scanning have expanded the repertory of genetic variations in DNA sequences encoding ErbB tyrosine kinase receptors in humans, including single nucleotide polymorphisms (SNPs), polymorphic repetitive elements ...
Moulay A Alaoui-Jamali, Gregoire Bernard Rene Morand, Sabrina Daniela Silva   +2 more
doaj   +1 more source

Detecting epistasis via Markov bases [PDF]

, 2010
Rapid research progress in genotyping techniques have allowed large genome-wide association studies. Existing methods often focus on determining associations between single loci and a specific phenotype.
Malaspinas, Anna-Sapfo, Uhler, Caroline
core   +1 more source

SKM-SNP: SNP markers detection method

Journal of Biomedical Informatics, 2010
SKM-SNP, SNP markers detection program, is proposed to identify a set of relevant SNPs for the association between a disease and multiple marker genotypes. We employ a subspace categorical clustering algorithm to compute a weight for each SNP in the group of patient samples and the group of normal samples, and use the weights to identify the subsets of
Liu, Y, Li, M, Cheung, YM, Ng, MK, Sham, PC   +4 more
openaire   +4 more sources

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, 2021
Aims. The determination of the contribution of precursor populations into the genetic structure of modern inbreds accoding to the results of DNA single nucleotide polymorphism analysis. Methods. SNP-genotyping of 5 maize inbreds with GoldenGate test, Illumina VeraCode, Sentrix array matrice, BDI-III-pannel of 384 SNP-markers, computer analysis by ...
  +6 more sources