Results 41 to 50 of about 527,601 (289)

Genetic variants in ELOVL2 and HSD17B12 predict melanoma‐specific survival [PDF]

, 2019
Fatty acids play a key role in cellular bioenergetics, membrane biosynthesis and intracellular signaling processes and thus may be involved in cancer development and progression.
Amos, Christopher I., Dai, Wei, Fang, Shenying, Jie, Ge, Lee, Jeffrey E., Li, Chunying, Li, Xin, Liu, Hongliang, Luo, Sheng, Nan, Hongmei, Wei, Qingyi, Xu, Xinyuan, Zhu, Dakai   +12 more
core   +1 more source

How much of the variation in the mutation rate along the human genome can be explained? [PDF]

, 2014
It has been claimed recently that it may be possible to predict the rate of de novo mutation of each site in the human genome with a high degree of accuracy [Michaelson et al. (2012), Cell 151: 143121442]. We show that this claim is unwarranted.
Eyre-Walker, Adam, Eyre-Walker, Ying Chen   +1 more
core   +1 more source

Two single nucleotide polymorphisms in the caprine GnIH gene are associated with litter size

Czech Journal of Animal Science, 2017
Gonadotropin-inhibitory hormone (GnIH) can decrease luteinizing hormone and/or follicle-stimulating hormone levels in rat, mouse, sheep, and cattle by the direct suppression of gonadotropin-releasing hormone (GnRH).
Xiaopeng An, Lijuan Bao, Jinxing Hou, Yueyu Bai, Xinyan Zhao, Yuxuan Song, Binyun Cao   +6 more
doaj   +1 more source

Association of a synonymous mutation of the PGAM2 gene and growth traits in rabbits

Czech Journal of Animal Science, 2015
Phosphoglycerate mutase (PGAM2) catalyzes the conversion of 3-phosphoglycerate into 2-phosphoglycerate and releases energy during glycolysis in muscle tissues.
Z.-L. Wu, S.-Y. Chen, X.-B. Jia, S.-J. Lai   +3 more
doaj   +1 more source

Association of bovine PPARGC1A and OPN genes with milk production and composition in Holstein cattle

Czech Journal of Animal Science, 2015
Several studies have reported quantitative trait loci on chromosome 6 affecting milk production and composition traits in dairy cattle. Osteopontin (OPN) and peroxisome proliferator activated receptor-γ coactivator-1α (PPARGC1A) genes have been located ...
M. Pasandideh, M.R. Mohammadabadi, A.K. Esmailizadeh, A. Tarang   +3 more
doaj   +1 more source

Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances [PDF]

, 2013
Twin and family studies indicate that the timing of primary tooth eruption is highly heritable, with estimates typically exceeding 80%. To identify variants involved in primary tooth eruption we performed a population based genome-wide association study ...
Alexei I. Zhurov, Anja Taanila, Anneli Pouta, Arshed M. Toma, Bakrania, Bayés de Luna, Beate St Pourcain, Bei, Bjarke Feenstra, Clive J. Hoggart, Cole, Cornelis, David M. Evans, Demetris Pillas, Di Cello, Eleftherohorinou, Eleftherohorinou, Elks, Ellen A. Nohr, Frank Geller, Freedman, Fujiwara, Geller, George Davey Smith, Ghazaleh Fatemifar, Golding, Goyal, Gu, Gudbjartsson, Hammarsund, Haraguchi, Hikake, Holmans, Horikoshi, Houlston, Hughes, Inga Prokopenko, Jernvall, Jia, John P. Kemp, Jon H. Tobias, Jussila, Kang, Kere, Kirsi Sipila, Lango Allen, Lavinia Paternoster, Levy, Li, Ligon, Mads Melbye, Marjo-Riitta Jarvelin, Meindl, Mikkola, Momoko Horikoshi, Mustonen, Nicholas J. Timpson, Nohr, Nunes, Nyholt, Paternoster, Pillas, Pispa, Pruim, Raija Lähdesmäki, Sabatti, Sakuraba, Simón-Sánchez, Soranzo, Srivastava, Stein, Stephen Richmond, Susan M. Ring, Taal, Taviaux, Tummers, Vainio, Vaz, Victoria J. Wright, Weedon, Willer, Wise, Yabe, Yang, Zhang   +84 more
core   +2 more sources

Identification of genome diversity in marandi chicken using whole genome sequencing method [PDF]

مجله بیوتکنولوژی کشاورزی, 2020
Objective Evaluation and conservation of native chickens as future genomic resources are essential. In this study, genomic diversity of four Marandi breeds was investigated using whole genome sequencing technique.
Rasol akbary, ali esmaeelizadeh, Zeinab Amiri Ghanatsaman, Ahmad Ayatollahi Mehrjerdi   +3 more
doaj   +1 more source

Verification and Analysis of Sheep Tail Type-Associated PDGF-D Gene Polymorphisms

Animals, 2020
The aim of this study was to examine the correlation between the platelet-derived growth factor-D (PDGF-D) gene and sheep tail type character and explore the potential underlying mechanism. A total of 533 sheep were included in this study.
Qing Li, Zengkui Lu, Meilin Jin, Xiaojuan Fei, Kai Quan, Yongbin Liu, Lin Ma, Mingxing Chu, Huihua Wang, Caihong Wei   +9 more
doaj   +1 more source

Large scale single nucleotide polymorphism discovery in unsequenced genomes using second generation high throughput sequencing technology: applied to turkey [PDF]

, 2009
Background - The development of second generation sequencing methods has enabled large scale DNA variation studies at moderate cost. For the high throughput discovery of single nucleotide polymorphisms (SNPs) in species lacking a sequenced reference ...
Kerstens, H.H.D., Crooijmans, R.P.M.A., Veenendaal, A., Dibbits, B.W., Chin-A-Woeng, T.F.C., Dunnen, J.T., den, Groenen, M.A.M.   +6 more
core   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source