Results 61 to 70 of about 499,359 (306)

Missense mutations in exon 2 of the porcine leptin receptor gene and their associations with litter size and body weight

Czech Journal of Animal Science, 2009
Leptin receptor (LEPR) gene is regarded as a "candidate-gene" of production traits. The aims of this study were to detect polymorphisms of exon 2 within LEPR gene and to investigate their associations with production traits, litter size and live weight ...
C. Sun, L. Wang, D. F. Jiang, B. Zhang
doaj   +1 more source

In silico analysis of CDC73 gene revealing 11 novel SNPs with possible association to Hyperparathyroidism-Jaw Tumor syndrome

The EuroBiotech Journal, 2020
Hyperparathyroidism-Jaw Tumor (HPT-JT) is an autosomal dominant disorder with variable expression, with an estimated prevalence of 6.7 per 1,000 population.
Abdelmoneim Abdelrahman H., Mohammed Alaa I., Gadim Esraa O., Mohammed Mayada Alhibir, Hamza Sara H., Mirghani Sara A., Mahmoud Thwayba A., Hassan Mohamed A.   +7 more
doaj   +1 more source

Predicting the effects of SNPs on transcription factor binding affinity

bioRxiv, 2019
GWAS have revealed that 88% of disease associated SNPs reside in noncoding regions. However, noncoding SNPs remain understudied, partly because they are challenging to prioritize for experimental validation.
Sierra S. Nishizaki, Natalie Ng, Shengcheng Dong, Cody Morterud, C. Williams, A. Boyle   +5 more
semanticscholar   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Methodological approaches to gene identification of tea raw materials and raw material composition of tea-based soft drinks

Пищевые системы
Tea or tea shrub is a plant of the Camellia sinensis species, the leaves of which, previously prepared in a special way, are the traditional raw material for the production of tea products.
R. R. Vafin, I. Yu. Mikhailova, I. I. Ageykina   +2 more
doaj   +1 more source

Identification and in silico analysis of functional SNPs of human TAGAP protein: A comprehensive study

PLoS ONE, 2018
Genetic polymorphisms in TAGAP gene have been associated with many diseases including rheumatoid arthritis, multiple sclerosis and other autoimmune disorders.
M. Arshad, A. Bhatti, P. John
semanticscholar   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Stearoyl-CoA Desaturase (SCD) Gene Diversity and Its Association with Fatty Acids in Bali Cattle Using PCR-RFLP Method

Jurnal Ilmu-Ilmu Peternakan
This study examines the Stearoyl-CoA desaturase (SCD) gene, which is essential for converting saturated fatty acids (SFA) into monounsaturated fatty acids (MUFA). The research aims to analyze the diversity of Single Nucleotide Polymorphism (SNP) g.10428C>
Annisa Sarwi, Ronny Rachman Noor, Jakaria Jakaria   +2 more
doaj   +1 more source

ASSOCIATION OF CERTAIN SINGLE NUCLEOTIDE POLYMORPHISM GENES OF APOPTOSIS SYSTEM WITH A RISK OF DEVELOPMENT OF COLORECTAL CANCER IN RUSSIAN POPULATION

Журнал микробиологии, эпидемиологии и иммунобиологии, 2016
Aim. Study the effect of single nucleotide polymorphism genes TP53 (rsl042522, rsl 800371), CDKN2A (rs3731217, rs3088440) and MDM2 (rs2279744) on the risk of development of colorectal cancer (CRC) in population of Perm Region. Materials and methods. Case
M. Kh. Alyeva, S. Ya. Zverev, I. V. Feldblyum, E. Yu. Noskova, A. O. Kanina, N. I. Markovich   +5 more
doaj   +1 more source

Rice SNP-seek database update: new SNPs, indels, and queries

Nucleic Acids Res., 2016
We describe updates to the Rice SNP-Seek Database since its first release. We ran a new SNP-calling pipeline followed by filtering that resulted in complete, base, filtered and core SNP datasets.
Locedie Mansueto, R. R. Fuentes, F. N. Borja, Jeffery Detras, Juan Miguel Abriol-Santos, D. Chebotarov, Millicent Sanciangco, Kevin Palis, D. Copetti, A. Poliakov, I. Dubchak, Victor V. Solovyev, R. Wing, R. Hamilton, R. Mauleon, Kenneth L. McNally, N. Alexandrov   +16 more
semanticscholar   +1 more source