Results 61 to 70 of about 527,601 (289)
Jurnal Ilmu-Ilmu PeternakanThis study examines the Stearoyl-CoA desaturase (SCD) gene, which is essential for converting saturated fatty acids (SFA) into monounsaturated fatty acids (MUFA). The research aims to analyze the diversity of Single Nucleotide Polymorphism (SNP) g.10428C>
Annisa Sarwi +2 more
doaj +1 more source
Журнал микробиологии, эпидемиологии и иммунобиологии, 2016 Aim. Study the effect of single nucleotide polymorphism genes TP53 (rsl042522, rsl 800371), CDKN2A (rs3731217, rs3088440) and MDM2 (rs2279744) on the risk of development of colorectal cancer (CRC) in population of Perm Region. Materials and methods. Case
M. Kh. Alyeva +5 more
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Electrochemical SNP detection [PDF]
Nucleic Acids Symposium Series, 2006 Detection of mismatched base on a DNA duplex, which is important for the search of the heterozygote, achieved by the comparison with the reactivity of ferrocenylcarbodiimide (1) developed by our group. Mismatched thymine base on the 30-meric DNA duplex as a model of SNPs in lipoprotein lipase (LPL) gene, could react with 1 in 20 mM borate buffer (pH 8 ...
Sadayoshi, Watanabe +4 more
openaire +2 more sources
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Czech Journal of Animal Science, 2021 PRDX6 is a bifunctional protein involved in antioxidant regulation and phospholipid metabolism. Previous studies have shown that PRDX6 is involved in some biological pathways and networks related to lactation.
Lihua Qiu +4 more
doaj +1 more source
Multiplex SNP Discrimination [PDF]
Biophysical Journal, 2007 Multiplex hybridization reactions of perfectly matched duplexes and duplexes containing a single basepair mismatch (SNPs) were investigated on DNA microarrays. Effects of duplex length, G-C percentage, and relative position of the SNP on duplex hybridization and SNP resolution were determined. Our theoretical model of multiplex hybridization accurately
Fish, Daniel J. +4 more
openaire +3 more sources
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Human platelet antigen polymorphisms and the risk of chronic Chagas disease cardiomyopathy
Platelets, 2020 Human platelet antigen (HPA) polymorphisms are considered to be a risk factor for cardiac and vascular diseases, but the role of HPA in chronic Chagas disease cardiomyopathy (CCC) is not available.
Deborah Elzita do Carmo Corrêa +8 more
doaj +1 more source
Towards the Human Genotope [PDF]
, 2006 The human genotope is the convex hull of all allele frequency vectors that can be obtained from the genotypes present in the human population. In this paper we take a few initial steps towards a description of this object, which may be fundamental for ...
Huggins, Peter +2 more
core +3 more sources