Results 61 to 70 of about 384,456 (306)
Functional polymorphisms in the TERT promoter are associated with risk of serous epithelial ovarian and breast cancers [PDF]
, 2011 Genetic variation at the TERT-CLPTM1L locus at 5p15.33 is associated with susceptibility to several cancers, including
epithelial ovarian cancer (EOC). We have carried out fine-mapping of this region in EOC which implicates an association with
a single Chaiwerawattana, A, Palmieri, RT, Beesley, Jonathan, Orlow, Irene, Pickett, Hilda A., Lophatananon, A, Kelemen Linda E., Rayna K Matsuno, Kiemeney, L.A.L.M., Ingo B Runnebaum, Lurie, G., Dörk Thilo, Aben, KKH, Despierre Evelyn, Wang-Gohrke, Shan, Le, ND, Kenneth Muir, Fridley Brooke L., Lurie, Galina, Wilkens, LR, Simon A. Gayther, Natalia Antonenkova, Chaiwerawattana, A., Kiemeney Lambertus A., Wilkens Lynne R., Marees Tamara, Chaiwerawattana, Arkom, Tamara Marees, Muir, K, Vierkant, R.A., Orlow Irene, Aben Katja K. H., Marc T Goodman, Campbell, I., Rodriguez-Rodriguez Lorna, Nickels, Stefan, Menon Usha, Dunning, A.M., Wiangnon, S., Usha Menon, Sandrina Lambrechts, null null, Angela Brooks-Wilson, Wiangnon, S, Robert A Vierkant, Jenny Chang-Claude, Vrieling Alina, HASH(0x55a67f4ed3f8), Ian Campbell, Lambrechts Diether, Olson Sara H., Paul D Pharoah, Georgia Chenevix-Trench, Campbell, I, Cook, LS, Lambrechts, D., Wiangnon Surapon, Alina Vrieling, Stutz, M.D., Macgregor, Stuart, Antonenkova Natalia, Olson, S.H., Lynne R. Wilkens, Despierre, E., Caroline Baynes, Michailidou, K., Wang-Gohrke, S., Aben, K.K.H., Despierre, E, Easton Douglas F., Vrieling, A, Menon, U., Ahmed, S, Ignace Vergote, Wiangnon, Surapon, Runnebaum, I.B., Linda S. Cook, Dunning, AM, Palmieri Rachel T., Goodman, MT, Roger R. Reddel, Massuger, Leon F. A. G., Easton, DF, Massuger, L.F.A.G., Bandera, EV, Ellen L Goode, Douglas F. Easton, Antonenkova, N., Vierkant Robert A., Australian Ovarian Can Study Grp, Massuger Leon F. A. G., Bandera Elisa V., Sara H. Olson, Ahmed, S., Pickett Hilda A., Dunning Alison M., Goodman Marc T., Rodriguez-Rodriguez, Lorna, Sharon E. Johnatty, Stutz, MD, Fridley, BL, Rodriguez-Rodriguez, L, Ramus Susan J., Le, Nhu D., Runnebaum Ingo B., Brooks-Wilson Angela, Jun Li, Simon A Gayther, Nickels, S., Pharoah, P.D., Muir, Kenneth (Kenneth R.), Michailidou, Kyriaki, Cook, Linda S., Chenevix-Trench, Georgia, Brooks-Wilson, A, Ellen L. Goode, Runnebaum, IB, Ramus, S.J., Bogdanova, N, Lu, Y., Arkom Chaiwerawattana, Rider, D.N., Chang-Claude, J, Gentry-Maharaj, Aleksandra, Natalia Bogdanova, Wilkens, Lynne R., Irene Orlow, Wilkens, L.R., Leon F. A. G. Massuger, Kyriaki Michailidou, Palmieri, Rachel T., Menon, U, Investigators kConFab, Gayther, Simon A., Thilo Dörk, David N Rider, Lambertus A. Kiemeney, Kiemeney, Lambertus A., Olson, Sara H., Flesch-Janys Dieter, Li, J, ABCTB Investigators, Wang-Gohrke, S, Le Nhu D., HASH(0x55a67f3e5a40), Johnatty, S.E., Vrieling, Alina, Dork, T., Stutz Michael D., Flesch-Janys, Dieter, Baynes, C., Marees, Tamara, Michael D. Stutz, Marees, T, David N. Rider, Ingo B. Runnebaum, Lophatananon, A., Baynes, Caroline, Lambrechts, S, Orlow, I, Li Jun, Matsuno Rayna K., Baynes, C, Li, Jun, Goode, Ellen L., Reddel Roger R., Katja K H Aben, Kelemen, L.E., Goode, E.L., Lambrechts, D, Antonenkova, Natalia, Matsuno, RK, Vergote, I, Lu, Yi, Le, N.D., Lurie Galina, Rayna K. Matsuno, Lophatananon, Artitaya, Lurie, G, Susan J. Ramus, Paul D. Pharoah, Brooke L. Fridley, Leon F A G Massuger, Vergote, Ignace, Artitaya Lophatananon, Brooks-Wilson, Angela, Jonathan Beesley, Beesley, J., Baynes Caroline, Rachel T Palmieri, Fridley, B.L., Elisa V Bandera, Eilber, Ursula, Antonenkova, N, Rodriguez-Rodriguez, L., Bogdanova, N., Alison M. Dunning, Chenevix-Trench, G, Diether Lambrechts, Rachel T. Palmieri, Goodman, Marc T., Johnatty, Sharon E., Kelemen, Linda E., Hilda A. Pickett, Brooke L Fridley, Xiaoqing Chen, Surapon Wiangnon, Eilber Ursula, Nickels, S, Li, J., Goodman, M.T., Chen Xiaoqing, Johnatty,Sharon E., Pharoah, Paul D., Bogdanova, Natalia, Cook, L.S., Chaiwerawattana Arkom, Robert A. Vierkant, Linda E. Kelemen, Matsuno, R.K., Fridley, Brooke L., Chen, Xiaoqing, Lorna Rodriguez-Rodriguez, Muir, K., Evelyn Despierre, Lambrechts, Diether, Lophatananon Artitaya, Pickett, HA, Michael D Stutz, Lu Yi, Reddel, RR, Flesch-Janys, D., Bogdanova Natalia, Susan J Ramus, Gayther Simon A., Eilber, U., Sara H Olson, Shan Wang-Gohrke, Beesley Jonathan, Stefan Nickels, Massuger, LFAG, Nhu D. Le, Bandera, E.V., Gayther, S.A., Marc T. Goodman, Flesch-Janys, D, Eilber, U, Lu, Y, Michailidou Kyriaki, Pharoah, PD, Aben, Katja K.H., Gentry-Maharaj, A, Beesley, J, Stuart Macgregor, Chang-Claude Jenny, Vierkant, RA, Campbell Ian, Yi Lu, Lambertus A Kiemeney, MacGregor, S., Shahana Ahmed, Campbell, Ian, Hilda A Pickett, Lambrechts, Sandrina, Macgregor, S, Matsuno, Rayna K., Pharoah Paul D., Vergote, I., Linda E Kelemen, Easton, Douglas F., Brooks-Wilson, A., Reddel, R.R., Lambrechts Sandrina, Australian Ovarian Cancer Study Group, Reddel, Roger R., Ovarian Canc Assoc Consortium, Wang-Gohrke Shan, Olson, SH, Ovarian Cancer Association Consortium, Lambrechts, S., Chen, XQ, Aben, Katja K. H., HASH(0x55a67f6cc8d8), Dieter Flesch-Janys, Gentry-Maharaj Aleksandra, Muir Kenneth, Rider, DN, Ahmed Shahana, Ramus, SJ, Linda S Cook, Dork, T, Sharon E Johnatty, Chenevix-Trench Georgia, Nhu D Le, Menon, Usha, Dörk, Thilo, Gentry-Maharaj, A., Stutz, Michael D., Despierre, Evelyn, Ramus, Susan J., Alison M Dunning, Cook Linda S., Marees, T., Kelemen, LE, Dunning, Alison M., Runnebaum, Ingo B., Chen, X., Michailidou, K, Chen, X, Katja K. H. Aben, Johnatty Sharon E., Chang-Claude, J., Nickels Stefan, Easton, D.F., Chang-Claude, Jenny, Douglas F Easton, Roger R Reddel, Palmieri, R.T., Ahmed, Shahana, Goode Ellen L., Rider, David N., Lynne R Wilkens, Vierkant, Robert A., Chenevix-Trench, G., Aleksandra Gentry-Maharaj, Bandera, Elisa V., Macgregor Stuart, Ursula Eilber, Vrieling, A., Vergote Ignace, Pickett, H.A., Elisa V. Bandera, Rider David N., Galina Lurie, kConFab Investigators, Goode, EL, Orlow, I., Johnatty, SE, Kiemeney, LA, Gayther, SA +339 morecore +1 more sourceLongitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay +15 morewiley +1 more sourceASSOCIATION OF CERTAIN SINGLE NUCLEOTIDE POLYMORPHISM GENES OF APOPTOSIS SYSTEM WITH A RISK OF DEVELOPMENT OF COLORECTAL CANCER IN RUSSIAN POPULATION
Журнал микробиологии, эпидемиологии и иммунобиологии, 2016 Aim. Study the effect of single nucleotide polymorphism genes TP53 (rsl042522, rsl 800371), CDKN2A (rs3731217, rs3088440) and MDM2 (rs2279744) on the risk of development of colorectal cancer (CRC) in population of Perm Region. Materials and methods. Case M. Kh. Alyeva, S. Ya. Zverev, I. V. Feldblyum, E. Yu. Noskova, A. O. Kanina, N. I. Markovich +5 moredoaj +1 more sourceClinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski +12 morewiley +1 more sourceLoss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann +11 morewiley +1 more sourceImpact of single nucleotide polymorphism on short stature and reduced tongue pressure among community-dwelling elderly Japanese participants: a cross-sectional study [PDF]
, 2017 Background: Asian-specific single nucleotide polymorphism (SNPs) (rs3782886) is reported to be associated with myocardial infarction; sarcopenia is reported to be associated with coronary subclinical atherosclerosis.Noguchi, Yuko, Kawashiri, Shin-Ya, Higashi, Miho, Jun Koyamatsu, Nagayoshi, Mako, Noboru Takamura, Yuji Shimizu, Koyamatsu, Jun, Mako Nagayoshi, Yuko Noguchi, Shimizu, Yuji, Maeda, Takahiro, Takahiro Maeda, Miho Higashi, Shin-Ya Kawashiri, Yamanashi, Hirotomo, Nagata, Yasuhiro, Yasuhiro Nagata, Sato, Shimpei, Hirotomo Yamanashi, Kadota, Koichiro, Takamura, Noboru, Shimpei Sato, Koichiro Kadota +23 morecore +1 more source
