Results 231 to 240 of about 5,755,630 (299)

Single-Nucleotide Polymorphisms in Genes Associated with Mitochondrial and DNA Damage Response Modulate the Risk of Non-Alcoholic Fatty Liver Disease in Humans. [PDF]

Int J Mol Sci
Ziółkowska S, Kosmalski M, Kołodziej Ł, Jarmusz K, Ejsmont M, Pietras T, Jabłkowska A, Jabłkowski M, Szemraj J, Czarny P.   +9 more
europepmc   +1 more source

Exploratory Analysis of Ancestry‐Informed Polygenic Risk Scores in Korean Patients With Mature B‐Cell Neoplasms

Journal of Clinical Laboratory Analysis, EarlyView.
In 246 Korean patients with mature B‐cell neoplasms, ancestry‐informed PRS analysis using the 1000 Genomes East Asian population as an external reference showed only a modest overall case–reference difference. In contrast, phenotype‐matched PRS revealed the clearest and most consistent polygenic association in multiple myeloma, highlighting the ...
Youngeun Lee, Bo Ra Son, Yong‐Pyo Lee, Jihyun Kwon, Hee Sue Park   +4 more
wiley   +1 more source

First report of novel single-nucleotide polymorphisms and genetic characteristics in the open reading frame of the prion protein gene (<i>PRNP</i>) in bats. [PDF]

Front Vet Sci
Tran DP, Choi DI, Na EJ, Oem JK, Jeong BH.   +4 more
europepmc   +1 more source

Association between ADHD symptoms and device‐measured physical activity and sedentary behavior in childhood: A population‐based twin study

JCPP Advances, EarlyView.
Abstract Background Attention‐deficit/hyperactivity disorder (ADHD) symptoms are associated with adverse health outcomes; this may be partially due to unhealthy lifestyle factors such as low physical activity (PA) and high sedentary behavior (SED). However, this association remains unclear.
Narda Ontiveros, Björg Helgadottir, Örjan Ekblom, Anna Ohlis, Aylin Mehren, Camilla A. Wiklund   +5 more
wiley   +1 more source

Multivariate genetic analyses test for the presence of a general ‘n’ factor underlying neurodevelopmental conditions

JCPP Advances, EarlyView.
Abstract Background Neurodevelopmental conditions often emerge early in life and have substantial genetic influences. There are significant genetic correlations between neurodevelopmental conditions, such as between autism spectrum disorder (Autism) and attention deficit‐hyperactivity disorder (ADHD), and they are listed together in diagnostic manuals.
Morgan James Morgan, Margherita Malanchini, Elise B. Robinson, Angelica Ronald   +3 more
wiley   +1 more source

Single Nucleotide Polymorphisms as Biomarkers of Response to Neoadjuvant Chemoradiotherapy in Rectal Cancer: A Systematic Review. [PDF]

Cancers (Basel)
Połomska K, Rybicka M, Jażdżewska A, Prud M, Jackowska S, Kobiela J, Spychalski P.   +6 more
europepmc   +1 more source

Offspring Global DNA Methylation is not Affected by Parental Developmental Stress Experience in a Passerine Species

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Rapid phenotypic change may be mediated by intergenerational transmission of early developmental experiences. In birds, exposure to glucocorticoids during early development can alter global DNA methylation and gene expression. However, DNA methylation is labile, and it is currently unclear whether the impacts of stress suffered during juvenile
Anna Miltiadous, Harrison J. F. Eyck, Ondi L. Crino, Lee A. Rollins, Damien Callahan, Katherine L. Buchanan   +5 more
wiley   +1 more source

Exploring Single-Nucleotide Polymorphisms in Primary and Secondary Male Infertility. [PDF]

Med Sci (Basel)
Dahadhah FW, Odeh M, Ali HA, Alzyoud JAM, Abu Alarjah MI.   +4 more
europepmc   +1 more source

Shared genetic and molecular architecture between neurodevelopmental disorders and type 1 diabetes

Journal of Intelligent Medicine, EarlyView.
Abstract Epidemiological and clinical studies have suggested possible associations between type 1 diabetes (T1D) and neurodevelopmental disorders (NDDs), but these relationships remain inconsistent across disorders and populations. To clarify whether such mixed findings, we investigated the genetic architecture linking T1D with autism spectrum disorder
Jingxuan Zhang, Zhentao Zhou, Lirong Zhu, Wei Liu   +3 more
wiley   +1 more source