Results 61 to 70 of about 5,755,630 (299)

The association between matrix metalloprotease-9 gene polymorphisms and primary angle-closure glaucoma in a Chinese Han population

International Journal of Ophthalmology, 2014
AIM:To examine the association between the single nucleotide polymorphisms (SNPs) of matrix metalloprotease-9 (MMP-9) gene and primary angle-closure glaucoma (PACG) in a Chinese Han population.METHODS: DNA samples were extracted from peripheral-blood ...
Xiao-Jin Gao, Sheng-Ping Hou, Ping-Hua Li   +2 more
doaj   +1 more source

Combined genotype analysis for three XRCC1 single nucleotide polymorphisms.

, 2018
Combined genotype analysis for three XRCC1 single nucleotide polymorphisms.
Yao Xiong (2156509), Shan Pan (677267), Lianying Ge (750001), Jiaxiang Ye (749997), Qian Zhang (49333)   +4 more
core   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

Single Nucleotide Polymorphisms in Pediatric Idiopathic Nephrotic Syndrome

International Journal of Nephrology, 2016
Polymorphic variants in several molecules involved in the glomerular function and drug metabolism have been implicated in the pathophysiology of pediatric idiopathic nephrotic syndrome (INS), but the results remain inconsistent.
Maija Suvanto, Timo Jahnukainen, Marjo Kestilä, Hannu Jalanko   +3 more
doaj   +1 more source

Association of prediabetes-associated single nucleotide polymorphisms with microalbuminuria.

PLoS ONE, 2017
Increased glycemic exposure, even below the diagnostic criteria for diabetes mellitus, is crucial in the pathogenesis of diabetic microvascular complications represented by microalbuminuria.
Jong Wook Choi, Shinje Moon, Eun Jung Jang, Chang Hwa Lee, Joon-Sung Park   +4 more
doaj   +1 more source

Single nucleotide polymorphisms as a prerequisite for autoantigens [PDF]

European Journal of Immunology, 2005
AbstractIt is still elusive why certain self proteins induce an autoimmune response. One immunological hypothesis is that only modified or altered self‐proteins may become a target. Thus, we asked whether such alterations may actually be genetic polymorphisms that can be revealed by analyzing sequence variability in the known human autoantigens. Indeed,
Stadler MB, Arnold D, Frieden S, Luginbühl S, Stadler BM   +4 more
openaire   +3 more sources

The Landscape of Long Non‐Coding RNAs Provides Insights Into the Domestication and Improvement of Pear Fruit

Advanced Science, EarlyView.
This study reveals that long non‐coding RNAs represent important regulatory components underlying pear domestication and improvement. Integrative multi‐omics analyses identify selected lncRNAs associated with fruit traits, while functional validation uncovers a lignin‐related lncRNA, lncRNA‐pys, that promotes lignin accumulation.
Bobo Song, Peilin Han, Jiaming Li, Xiaolong Li, Xiang Zhang, Jing Fan, Dongliang Liu, Jianfa Cai, Lingchao Zhang, Jun Wu   +9 more
wiley   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

Single Nucleotide Polymorphism (SNP) และ DNA Polymorphisms

Journal of Associated Medical Sciences, 2015
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Songyot Anuchapreeda
doaj  

Single nucleotide polymorphisms used to define each haplogroup.

, 2016
Single nucleotide polymorphisms used to define each haplogroup.
Micheala A. Aldred (2806378), Bo Hu (126105), Serpil C. Erzurum (352157), Samar Farha (2806372), Suzy Comhair (337321), Joe Zein (2806369), Raed Dweik (2806375)   +6 more
core   +1 more source