Results 31 to 40 of about 58,343 (263)

Single-Photon Detectors on Arbitrary Photonic Substrates

open access: yesACS Photonics
11 pages, 12 ...
Max Tao   +18 more
openaire   +3 more sources

Measurement of focal light spot at single-photon level with silicon photomultipliers

open access: yesScientific Reports, 2022
Focal spot (light spot) at single-photon level have important applications in many fields. This report demonstrates a method for measuring focal spot size at the single-photon level indirectly.
Guoqing Zhang   +6 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Superconducting single-photon detectors fabricated via a focused electron beam-induced deposition process

open access: yesAIP Advances, 2023
Superconducting detectors have become essential devices for high-performance single-photon counting over a wide wavelength range with excellent time resolution.
Stephan Steinhauer   +3 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Photon-Counting Underwater Optical Wireless Communication for Reliable Video Transmission Using Joint Source-Channel Coding Based on Distributed Compressive Sensing

open access: yesSensors, 2019
To achieve long-distance underwater optical wireless communication, a single photon detector with single photon limit sensitivity is used to detect the optical signal at the receiver.
Zhu Hong   +4 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Heterodyne spectroscopy with superconducting single-photon detector

open access: yesEPJ Web of Conferences, 2017
We demonstrate successful operation of a Superconducting Single Photon Detector (SSPD) as the core element in a heterodyne receiver. Irradiating the SSPD by both a local oscillator power and signal power simultaneously, we observed beat signal at the ...
Lobanov Yu.V.   +5 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

High-quality photon-limited imaging through dynamic and complex scattering media with a single-photon detector [PDF]

open access: yesAPL Photonics
Recent advances in single-photon detectors have enabled low-light detection in diverse applications ranging from biological imaging to astronomy. However, it remains a challenge to realizing high-quality optical imaging through dynamic and complex ...
Yining Hao   +3 more
doaj   +1 more source

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