Results 51 to 60 of about 58,343 (263)

Confocal-based fluorescence fluctuation spectroscopy with a SPAD array detector

open access: yesLight: Science & Applications, 2021
The combination of confocal laser-scanning microscopy (CLSM) and fluorescence fluctuation spectroscopy (FFS) is a powerful tool in studying fast, sub-resolution biomolecular processes in living cells.
Eli Slenders   +7 more
doaj   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

open access: yesFEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie   +8 more
wiley   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

Automated Characterization of Single-Photon Avalanche Photodiode

open access: yesInternational Islamic University Malaysia Engineering Journal, 2012
We report an automated characterization of a single-photon detector based on commercial silicon avalanche photodiode (PerkinElmer C30902SH). The photodiode is characterized by I-V curves at different illumination levels (darkness, 10 pW and 10 µW), dark ...
Aina Mardhiyah M. Ghazali   +3 more
doaj   +1 more source

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez   +5 more
wiley   +1 more source

Multimode Fiber Coupled Superconductor Nanowire Single-Photon Detector

open access: yesIEEE Photonics Journal, 2014
High-performance superconductor nanowire single-photon detectors (SNSPDs) coupled by 50-μm multimode fiber were designed and fabricated for the purpose of space applications.
Labao Zhang   +7 more
doaj   +1 more source

Fast-Gated 16 × 1 SPAD Array for Non-Line-of-Sight Imaging Applications

open access: yesInstruments, 2020
In this paper we present a novel single-photon detector specifically designed for Non-Line-Of-Sight (NLOS) imaging applications within the framework of the DARPA REVEAL program.
Marco Renna   +5 more
doaj   +1 more source

Density Measurement of Irradiated and Nonirradiated Zirconium Oxide by Ptychographic X‐Ray Computed Tomography (PXCT)

open access: yesAdvanced Engineering Materials, EarlyView.
Mass density governs the protective behavior of oxide layers on nuclear fuel cladding. Ptychographic X‐ray computed tomography measures zirconium oxide grown on Zircaloy‐4 under reactor and autoclave conditions, revealing nearly identical bulk densities of 5.1 ± 0.80 g cm−3.
Okan Yetik   +9 more
wiley   +1 more source

Single-photon detectors combining high efficiency, high detection rates, and ultra-high timing resolution

open access: yesAPL Photonics, 2017
Single-photon detection with high efficiency, high time resolution, low dark counts, and high photon detection rates is crucial for a wide range of optical measurements.
Iman Esmaeil Zadeh   +7 more
doaj   +1 more source

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