Results 111 to 120 of about 4,995,337 (307)

Influence of hammering pile driving on overall bending resistance of single-sided welded piles

open access: yesYantu gongcheng xuebao
In order to study the influences of hammering pile driving on the overall anti-bending performance of PHC piles with single-side welded joints after construction, field pile driving tests and full-scale anti-bending tests are conducted.
XIA Gaoxiang 1 , GUAN Yunfei 2, LIU Jiangzhen 2, CHEN Pinzhang 1, CHEN Shengyuan 2, LI Fuzhong 1
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Single Piles and Pile Groups Under Lateral Loading [PDF]

open access: yesApplied Mechanics Reviews, 2002
LC Reese,, WF Van Impe,, RD Holtz,
openaire   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Manly [cartographic material] : 7 villa sites near tram line, ocean views 12/6 per foot /

open access: yes, 1890
Sales plan for land in the suburb of Queenscliff in Sydney bounded by Pittwater Road, Queenscliff Road and Pavillion Street.; "Torrens title."; Also available in an electronic version via the internet at: http://nla.gov.au/nla.map ...
Pile, G.
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Fairview Estate, Manly [cartographic material] : for sale on the ground /

open access: yes, 1885
Sales plan for land in the suburb of Manly in Sydney bounded by The Corso, Esplanade, The Crescent, Fairlight Street and George Street.; "Terms, 10% deposit, balance in 12 quarterly payments, interest 5%."; Also available in an electronic version via the
Mills & Pile.
core  

Modified Sheet Pile Abutments for Low-Volume Road Bridges: TR-568, January 2012 [PDF]

open access: yes, 2012
To date there have been few investigations of the substructures in low-volume road (LVR) bridges. Steel sheet piling has the potential to provide an economical alternative to concrete bridge abutments, but it needs investigation with regard to vertical ...

core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

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