Results 31 to 40 of about 18,790 (265)

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Comparative Experimental Study on Bearing Capacity of Roof Beneath Single Piles and Pile Groups in Karst Area

Buildings
By designing and conducting indoor model tests on single piles and 2 × 2 pile groups under four working conditions—underlying cave, overlying cave, pile penetrating underlying cave, and beaded caves—the failure mode of the roof was explored, and its ...
Xinquan Wang, Haitao Chen, Haibo Hu, Chen Liu, Yongle Tian, Jun Hong   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Analytical method for single pile under V-H-M combined loads in sand

Yantu gongcheng xuebao, 2017
The large-diameter monopiles of offshore wind turbines are always subjected to multiaxial loads. The design criteria for the vertical and lateral bearing behaviors of piles are designed independently, while lots of tests show that the vertical load has a
MU Lin-long 1, 2, KANG Xing-yu 1, 2, LI Wan 1, 2
doaj   +1 more source

Analysis of the Bearing Characteristics of Single Piles under Vertical and Torsional Combined Loads

Advances in Civil Engineering, 2021
To investigate the bearing characteristics of single piles under the combined action of vertical loads (V) and torque (T) on a pile head, the displacement governing equations of the pile shaft were proposed in consideration of the load transfer method ...
Shun-Wei Wang, Jie Jiang, Chen-Zhi Fu, Xiao-Duo Ou, Juan Tang   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Failure mechanism and setback distance of single pile subjected to normal faulting

Yantu gongcheng xuebao, 2017
Field case studies after earthquake show that pile foundation can be severely damaged by bedrock fault movement. The failure mechanism of this type of foundation damage is not yet fully understood.
CAI Qi-peng 1, NG C. W. W. 2, CHEN Xing-xin 1, GUO Li-qun 1
doaj   +1 more source

Numerical Simulation Research on the Vertical Bearing Capacity of the Single Pile Foundation in Zhugensha Sea Area

南方能源建设, 2021
[Introduction] Wind power projects in Jiangsu Province are mainly located in the offshore radiant sandbank sea area. It is of great significance to study the bearing capacity of the large diameter single pile in this stratum.
ZHANG Qiang, GE Chang, SHEN Xiaolei, SHANG Jin   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source