Results 51 to 60 of about 18,790 (265)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Management of Pile End Sediment and Its Influence on the Bearing Characteristics of Bored Pile

Buildings
In order to study the influence of pile end sediment on the bearing characteristics of bored piles, the on-site bearing capacity test was conducted on a single pile.
Weibin Song, Zhengzhen Wang, Wentao Zhu, Junping Yang, Jianming Zeng   +4 more
doaj   +1 more source

3D FAILURE ENVELOPE OF A SINGLE PILE IN SAND [PDF]

Proceedings of the 5th International Conference on Computational Methods in Structural Dynamics and Earthquake Engineering (COMPDYN 2015), 2015
Pile foundations are widely used in geotechnical and offshore engineering. When subjected to a combination of horizontal, vertical forces and bending moments, a 3D failure envelope is necessary in order to evaluate the safety of the pile-soil system. We present a study on the failure envelope of a single elastic pile in sand. In order to find it in the
Li, Zheng, Kotronis, Panagiotis, Escoffier, Sandra   +2 more
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Research on Bearing Characteristics of Open-Ended Pipe Piles under Static Load

Advances in Civil Engineering, 2021
The accurate estimate of the ultimate bearing capacity of a single pile in the vertical direction is an important issue in the design of the pile foundation. This paper presents a static test on a single-pile model. The test was performed through a large-
Haibao Feng, Xingke Dai, Shuiyue Chen, Jianwei Chen   +3 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

BEHAVIOR OF MODEL GROUP PILES SUBJECTED TO LATERAL SOIL MOVEMENT IN SAND

Journal of Engineering and Sustainable Development, 2017
Laboratory model tests have been carried out to explore the behavior of piles subjected to lateral soil movement in sand. The results of a single pile test and ten tests on of group piles arranged in a row (perpendicular to the direction of soil ...
Saad Farhan Ibraheem, Mohammed Khachi Hatem   +1 more
doaj  

Effect of periodic vibration-isolation piles on soil vibration in deep-buried tunnels of suburban railways

Science Progress
This study aims to investigate the impact of isolation piles on soil vibrations in the environment surrounding suburban railways. Initially, a comprehensive numerical model of the train was established to simulate the wheel-rail interaction forces, which
Shusen Cao, Dong Li, Jili Yin, Qin Xu, Dongdong Qian, Chao Chen, Hongkai Wang, Lunzheng Zhang, Xiangdong Shi, Futong Wang   +9 more
doaj   +1 more source

An Investigation into the Lateral Bearing Performance of a Single Pile Embedded at a Three-Dimensional Asymmetric Local Scour Site Using the Modified Strain Wedge Model

Applied Sciences
The scouring effect is widely acknowledged as a primary contributor to the weakening in the bearing performance of offshore piles; it often results in asymmetric scour patterns around the pile.
Songyang Wang, Jianjun Ma, Chaosheng Wang, Fengjun Liu, Da Li   +4 more
doaj   +1 more source