Results 101 to 110 of about 8,902,818 (343)

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Ultrafast structural dynamics of carbon–carbon single-bond rotation in transient radical species at non-equilibrium

Nature Communications
Bond rotation is an important phenomenon governing the fate of reactions. In particular, heterogeneously substituted ethane derivatives provide distinct structural conformations around the bond, empowering them as ideal systems for studying the rotation ...
Seonggon Lee, Hosung Ki, Donghwan Im, Jungmin Kim, Yunbeom Lee, Jain Gu, Alekos Segalina, Jun Heo, Yongjun Cha, Kyung Won Lee, Doyeong Kim, Jeongho Kim, Rory Ma, Jae Hyuk Lee, Hyotcherl Ihee   +14 more
doaj   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

27 Use of rotational atherectomy in primary pci for st-elevation myocardial infarction- a single centre 10-year experience [PDF]

, 2017
MM Mahmood, Qureshi Ma, Robert Morley, David Austin, J Carter, MA de Belder, JA Hall, DF Muir, Neil Swanson, A G C Sutton, Paul D. Williams, RA Wright   +11 more
openalex   +1 more source

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

Arthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier, Matthew N. Vigliotti, Paige E. Rice, Brian Pietrosimone, Shannon L. Mihalko, Edward H. Ip, Richard F. Loeser, David J. Hunter, Ali Guermazi, Ryan Hill, Santiago Saldana, Kim L. Bennell, Paul DeVita   +12 more
wiley   +1 more source

Enhanced Faraday rotation and magneto-optical figure of merit in gold grating/graphene/silicon hybrid magneto-plasmonic devices

APL Photonics, 2018
Graphene is a promising THz magneto-optical material. However, high Faraday rotation is only achievable at a low THz frequency range in single layer graphene.
Jun Qin, Shuang Xia, Ke Jia, Chuangtang Wang, Tingting Tang, Haipeng Lu, Li Zhang, Peiheng Zhou, Bo Peng, Longjiang Deng, Lei Bi   +10 more
doaj   +1 more source

Current Tracking Adaptive Control of Brushless DC Motors

International Journal of Adaptive Control and Signal Processing, EarlyView.
In this paper, the current tracking for Brushless Direct Current motors is approached considering uncertainty in the parameters of the motor's model. An adaptive control scheme to compensate electrical parameters uncertainty is proposed without requiring any knowledge of the mechanical parameters.
Fernanda Ramos‐García, Axel Coronado‐Andrade, Gerardo Espinosa‐Pérez, Luis Alvarez‐Icaza   +3 more
wiley   +1 more source

Bistable Mechanisms 3D Printing for Mechanically Programmable Vibration Control

Advanced Engineering Materials, EarlyView.
This work introduces a 3D‐printed bistable mechanism integrated into tuned mass dampers (TMDs) for mechanically adaptive passive vibration suppression. Through optimized geometry, the bistable design provides adaptable vibration reduction across a broad range of scenarios, achieving effective vibration mitigation without complex controls or external ...
Ali Zolfagharian, Frédéric Demoly, Mohammad Lakhi, Bernard Rolfe, Mahdi Bodaghi   +4 more
wiley   +1 more source

Flare Activity and Magnetic Feature Analysis of the Flare Stars. III. K-type Dwarf Binary Components

The Astrophysical Journal
We analyze the light curve of 199 dwarf stars that are members of binary systems resolved by Kepler mission. All of them are K-type active stars in binary systems of which their flare activity has been confirmed.
Hadis Goodarzi, Ahmad Mehrabi, Habib G. Khosroshahi   +2 more
doaj   +1 more source

Robust Single Rotation Averaging Revisited

In this work, we propose a novel method for robust single rotation averaging that can efficiently handle an extremely large fraction of outliers. Our approach is to minimize the total truncated least unsquared deviations (TLUD) cost of geodesic distances.
Seong Hun Lee, Javier Civera
openaire   +2 more sources