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s Because of remarkable advances in survival over the past 40 years, the worldwide population of individuals with single ventricle heart disease living with Fontan circulation has grown to ≈70 000, with nearly half aged >18 years. Survival to at least 30
Sushma Reddy +4 more
doaj +2 more sources
A randomised trial of early palliative care for maternal stress in infants prenatally diagnosed with single-ventricle heart disease [PDF]
Children with single-ventricle disease experience high mortality and complex care. In other life-limiting childhood illnesses, paediatric palliative care may mitigate maternal stress.
Aiyagari, Ranjit +10 more
core +3 more sources
The Pulmonary Circulation in the Single Ventricle Patient
In recent decades, survival of children with complex congenital heart disease has improved considerably. Specifically, children with a variety of congenital heart defects resulting in ‘single ventricle’ physiology can now undergo palliative surgery that ...
Amanda Hauck +3 more
doaj +2 more sources
Pulmonary Vasodilator Therapy in Children with Single Ventricle Physiology: Effects on Saturation and Pulmonary Arterial Pressure [PDF]
In children with single ventricle physiology, increased pulmonary vascular resistance may impede surgical progression or result in failing single ventricle physiology. The use of pulmonary vasodilators has been suggested as a potential therapy.
Ida Jeremiasen +4 more
openalex +2 more sources
Mid-term result of atrioventricular valve replacement in patients with a single ventricle† [PDF]
Koichi Sughimoto +7 more
openalex +2 more sources
Narrative review of single ventricle: where are we after 40 years?
Background and Objective Key medical and surgical advances have been made in the longitudinal management of patients with “functionally” single ventricle physiology, with the principles of Fontan circulation applied to other complex congenital heart ...
A. Corno, Tina O Findley, J. Salazar
semanticscholar +1 more source
Effects of cardiac growth on electrical dyssynchrony in the single ventricle patient
Single ventricle patients, including those with hypoplastic left heart syndrome (HLHS), typically undergo three palliative heart surgeries culminating in the Fontan procedure.
O. Z. Tikenogullari +5 more
semanticscholar +1 more source
Impact of Maternal–Fetal Environment on Mortality in Children With Single Ventricle Heart Disease
BACKGROUND Children with single ventricle heart disease have significant morbidity and mortality. The maternal–fetal environment (MFE) may adversely impact outcomes after neonatal cardiac surgery.
Jill J. Savla +10 more
semanticscholar +1 more source
Lymphatic Disorders in Patients With Single Ventricle Heart Disease
Lymphatic abnormalities in patients with single ventricle physiology can lead to early Fontan failure and severe Fontan complications, such as protein-losing enteropathy (PLE), plastic bronchitis (PB), chylothorax, and edema.
Y. Dori, Christopher L. Smith
semanticscholar +1 more source
OBJECTIVES A conclusive interpretation of the role of ventricular dominance in outcomes after Fontan palliation has not been formulated yet. We conducted a systematic review and meta-analysis of scientific literature to give an insight into the impact of
M. Ponzoni +7 more
semanticscholar +1 more source

