Results 41 to 50 of about 7,078,310 (387)

Histone deacetylase adaptation in single ventricle heart disease and a young animal model of right ventricular hypertrophy. [PDF]

, 2017
BackgroundHistone deacetylase (HDAC) inhibitors are promising therapeutics for various forms of cardiac diseases. The purpose of this study was to assess cardiac HDAC catalytic activity and expression in children with single ventricle (SV) heart disease ...
A Cevik, A Correa-Villasenor, A deAlmeida, A Granger, A Kulkarni, AP Vlahos, C Scholz, Carlin S Long, CL Antos, D Sedmera, DD Lemon, DJ Cao, Douglas D Lemon, J Lu, JP Cardinale, JW Newburger, JW Rossano, JW Rossano, Karin Nunley, Katharina M Lutter, KB Schuetze, Kimberly M Demos-Davies, KM Demos-Davies, M Tanno, MA Cavasin, MA Cavasin, Maria A Cavasin, MP Gupta, OA O'Connor, PA Marks, PC Frommelt, Q Yang, R Kirk, RG Ohye, S Chen, Sam Payne, SD Miyamoto, SD Miyamoto, SD Miyamoto, Shelley D Miyamoto, SJ Nakano, SK Mani, SM Williams, TA McKinsey, TG Gillette, Timothy A McKinsey, VM Klimek, Weston W Blakeslee, WJ Kowalski, WW Blakeslee   +49 more
core   +1 more source

Single ventricle, many arrhythmias [PDF]

Journal of Thoracic Disease, 2018
As the wheels of progress churn forward in cardiovascular care and cardiac surgical technique, the survival rate for infants born with single ventricle physiology, once a universally fatal disease, has improved dramatically. The single ventricle reconstruction (SVR) trial recently reported an overall survival in these patients of 62% at 6 years of ...
Robert, Whitehill, Peter, Fischbach, Matthew E, Oster   +2 more
openaire   +2 more sources

Safety and Efficacy of Sacubitril/Valsartan in Patients With a Failing Systemic Right Ventricle: A Prospective Single-Center Study

Circulation: Heart Failure, 2022
Background: Sacubitril/valsartan was demonstrated to reduce hospitalization rate and mortality in patients with heart failure with reduced ejection fraction.
F. Fusco, G. Scognamiglio, A. Merola, A. Iannuzzi, M. Palma, N. Grimaldi, B. Sarubbi   +6 more
semanticscholar   +1 more source

Association of Digoxin Use With Transplant‐Free Interstage Survival in Infants Palliated With a Stage 1 Hybrid Procedure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Digoxin prescription in patients with single‐ventricle physiology after stage 1 palliation is associated with reduced interstage death. Prior literature has primarily included patients having undergone the Norwood procedure.
Reshma K. Reddy, Sinai C. Zyblewski, Shahryar M. Chowdhury, Justin Godown, Scott M. Bradley, David W. Brown, Rachel K. Duncan, Tyler N. Brown, Katherine E. Bates, L. LuAnn Minich, John M. Costello   +10 more
doaj   +1 more source

Ventricular Assist Device Implantation for Single Ventricle

Operative techniques in thoracic and cardiovascular surgery, 2020
Due to the increasing number of patients with failing single ventricle physiology, there has been a growing interest in the use of ventricular assist device (VAD) in these patients.
I. Adachi
semanticscholar   +1 more source

Exercising with a Single Ventricle: Limitations and Therapies

Journal of Cardiovascular Development and Disease, 2022
Treatment for Hypoplastic Left Heart Syndrome (HLHS) and other single ventricle conditions requires a series of surgical interventions for long-term survival, typically culminating in the Fontan procedure. The result is an abnormal circulatory physiology
Jessica Erin Haley, Christopher Davis
doaj   +1 more source

A case of single ventricular heart, pulmonary atresia, patent ductus arteriosus, major aortopulmonary collateral arteries

Asian Journal of Medical Sciences, 2015
We report a case of multiple congenital anomalies in a female newborn infant, born to themother from a hill tribe. The Doppler echocardiography of the baby showed large atrial septaldefect amounting to single atrium, atretic left atrioventricular valve ...
Rema V Nair
doaj   +1 more source

Arrhythmias in children with a single ventricle

Бюллетень сибирской медицины, 2018
Aim. The paper presents prevalence and disturbances of cardiac rhythm and conduction in children with a single ventricle (SV) at different stages of hemodynamic defect correction. It also analyzes risk factors of arrhythmia.Materials and methods. A total
I. V. Plotnikova, O. Yu. Dzhaffarova, L. I. Svintsova, V. V. Saushkin, I. A. Kovalev   +4 more
doaj   +1 more source

Review on Mechanical Support and Cell-Based Therapies for the Prevention and Recovery of the Failed Fontan-Kreutzer Circulation

Frontiers in Pediatrics, 2021
Though the current staged surgical strategy for palliation of single ventricle heart disease, culminating in a Fontan circulation, has increased short-term survival, mounting evidence has shown that the single ventricle, especially a morphologic right ...
Margaret R. Ferrari, Michael V. Di Maria, Jeffrey G. Jacot, Jeffrey G. Jacot   +3 more
doaj   +1 more source

The cell cycle–apoptosis connection revisited in the adult brain [PDF]

, 2005
Adult neurogenesis is studied in vivo using thymidine analogues such as bromodeoxyuridine (BrdU) to label DNA synthesis during the S phase of the cell cycle.
Bauer, Sylvian, Patterson, Paul H.
core   +3 more sources