Results 41 to 50 of about 133,578 (262)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

An Out of Memory tSVD for Big-Data Factorization

open access: yesIEEE Access, 2020
Singular value decomposition (SVD) is a matrix factorization method widely used for dimension reduction, data analytics, information retrieval, and unsupervised learning.
Hector Carrillo-Cabada   +4 more
doaj   +1 more source

Chern Numbers for Singular Varieties and Elliptic Homology [PDF]

open access: yesThe Annals of Mathematics, 2000
35 pages, published version, abstract added in ...
openaire   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The category of Number in Basque: II. Prehistoriacal and typological aspects

open access: yesFontes Linguae Vasconum, 2020
In this second and last part of the article about the grammatical number in Basque, it is discussed what the state of affairs in prehistorical periods may have been like, taking historical data as a starting point.
Mikel Martínez Areta
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Research on rolling bearing fault diagnosis technology based on singular value decomposition

open access: yesAIP Advances
To solve the difficulty of selecting the number of effective singular values in Singular Value Decomposition denoising, a new method to determine the number of effective singular values is proposed.
Jingfang Ji, Jingmin Ge
doaj   +1 more source

Singularities of base polynomials and Gau–Wu numbers

open access: yesLinear Algebra and its Applications, 2019
In 2013, Gau and Wu introduced a unitary invariant, denoted by $k(A)$, of an $n\times n$ matrix $A$, which counts the maximal number of orthonormal vectors $\textbf x_j$ such that the scalar products $\langle A\textbf x_j,\textbf x_j\rangle$ lie on the boundary of the numerical range $W(A)$.
Camenga, Kristin A.   +5 more
openaire   +4 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Rigidez de una superficie con puntos singulares

open access: yesRevista de Matemática: Teoría y Aplicaciones, 2009
The infinitesimal isometric deformations of a type of surface with singular points are considered and a sufficient condition of rigidity of such surfaces is demonstrated. Keywords: Surface with singular points, Gauss formula, typical number.
Elena Chkryl
doaj   +1 more source

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