Results 61 to 70 of about 133,578 (262)

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

APPARENT CONTOURS WITH MINIMAL NUMBER OF SINGULARITIES

open access: yesKyushu Journal of Mathematics, 2009
Summary: For a stable map \(\varphi : M \to S^{2}\) of a closed and connected surface into the sphere, let \(c(\varphi ), i(\varphi )\) and \(n(\varphi )\) denote the numbers of cusps, fold curve components and nodes respectively. In this paper, in a given homotopy class, we will determine the minimal triples \((c, i, n), (n, c, i)\) and \((i, n, c ...
openaire   +2 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

ON THE NUMBER OF CREPANT VALUATIONS OF CANONICAL SINGULARITIES

open access: yesJournal of the London Mathematical Society, 2003
In this note we calculate the number of crepant valuations of an isolated canonical singularity 0 ∈ X : (f = 0) ⊂ Cn, which is assumed to be nondegenerate with respect to its Newton polyhedron, in terms of weightings and the Newton polyhedron of f.
openaire   +2 more sources

Milnor numbers for surface singularities [PDF]

open access: yesIsrael Journal of Mathematics, 2000
An additive formula for the Milnor number of an isolated complex hypersurface singularity is shown. We apply this formula for studying surface singularities. Durfee's conjecture is proved for any absolutely isolated surface and a generalization of Yomdin singularities is given.
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

On the number of limit cycles for systems with several singular points

open access: yesJournal of Numerical Analysis and Approximation Theory, 1987
Not available.
Nicolae Lungu
doaj   +2 more sources

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

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