Results 51 to 60 of about 32,350 (292)
Change Point Detection in Time Series via Multivariate Singular Spectrum Analysis [PDF]
The objective of change-point detection (CPD) is to estimate the time of significant and abrupt changes in the dynamics of a system through multivariate time series observations. The setup of CPD covers a wide range of real-world problems such as quality
AlAnqary, Arwa
core
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Ant-Colony-Based Multiuser Detection for MC DS-CDMA Systems [PDF]
In this contribution we present a novel ant colony optimization (ACO) based multi-user detector (MUD) designed for synchronous multi-carrier direct sequence code division multiple access (MC DSCDMA) systems. The operation of the ACO-based MUD is based on
Chong Xu +5 more
core +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Singular point detection of energy losses in hard magnetic materials [PDF]
The real and the imaginary part of the reversible parallel susceptibility (RPS) and it harmonics was measured using the modulation technique.
Asti G., Ghidini M., Solzi M.
core
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Indoor Localization Using Visible Light Via Fusion of Multiple Classifiers
We propose a localization technique by fusing multiple classifiers based on received signal strengths (RSSs) of visible light in which different intensity-modulated sinusoidal signals emitted by LEDs are captured by photodiodes placed at various grid ...
Xiansheng Guo +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source

