Results 31 to 40 of about 75,343 (266)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
For studying the stress-strain state at singular points and their neighborhoods new concept is proposed. A singular point is identified with an elementary volume that has a characteristic size of the real body representative volume.
V. Pestrenin, I. Pestrenina, L. Landik
doaj +1 more source
Singular Points of the Tremor of the Earth’s Surface
A method for studying properties of the Earth’s surface tremor, measured by means of GPS, is proposed. The following tremor characteristics are considered: the entropy of wavelet coefficients, the Donoho–Johnston wavelet index, and two estimates of the ...
Alexey Lyubushin
doaj +1 more source
Walking to singular points of fingerprints
Singular point is an essential global feature in fingerprint images. Existing methods for singular points' detection generally visit each pixel or each small image block to determine the singular point. That is to say, existing methods require scanning the image to compute a quantity at each pixel or block, and hence they are inevitably time-consuming.
En Zhu, Xifeng Guo 0001, Jianping Yin
openaire +2 more sources
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
When singular points determine quadratic systems
When one considers a quadratic differential system, one realizes that it depends on 12 parameters of which one can be fixed by means of a time change.
Nicolae Vulpe +2 more
doaj
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source

