Results 31 to 40 of about 75,924 (265)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Stress State at the Vertex of a Composite Wedge, One Side of Which Slides Without Friction Along a Rigid Surface

open access: yesLatin American Journal of Solids and Structures
For studying the stress-strain state at singular points and their neighborhoods new concept is proposed. A singular point is identified with an elementary volume that has a characteristic size of the real body representative volume.
V. Pestrenin, I. Pestrenina, L. Landik
doaj   +1 more source

The Index and Split Forms of Linear Differential-Algebraic Equations

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2019
We consider linear systems of ordinary differential equations (ODE) with rectangular matrices of coefficients, including the case when the matrix before the derivative of the desired vector function is not full rank for all argument values from the ...
M.V. Bulatov, V.F. Chistyakov
doaj   +1 more source

Singular Points of the Tremor of the Earth’s Surface

open access: yesApplied Sciences, 2023
A method for studying properties of the Earth’s surface tremor, measured by means of GPS, is proposed. The following tremor characteristics are considered: the entropy of wavelet coefficients, the Donoho–Johnston wavelet index, and two estimates of the ...
Alexey Lyubushin
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

When singular points determine quadratic systems

open access: yesElectronic Journal of Differential Equations, 2008
When one considers a quadratic differential system, one realizes that it depends on 12 parameters of which one can be fixed by means of a time change.
Nicolae Vulpe   +2 more
doaj  

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