Results 51 to 60 of about 2,579,903 (296)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Singular bielliptic curves and Weierstrass points

open access: yesLe Matematiche, 1999
Here we study the Weierstrass points of singular bielliptic curves in characteristic 0. Most of our results are existence results of the type "there exists a bielliptic curve Y with certain singular points and with a weierstrass point P ∈ Y_{reg} with a ...
Edoardo Ballico
doaj  

Singular polynomials from orbit spaces [PDF]

open access: yes, 2012
We consider the polynomial representation S(V*) of the rational Cherednik algebra H_c(W) associated to a finite Coxeter group W at constant parameter c.
Feigin, M., Silantyev, A.
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Trajectories and Singular Points of Two-Dimensional Fractional-Order Autonomous Systems

open access: yesAdvances in Mathematical Physics, 2022
In this paper, we study the trajectories and singular points of two-dimensional fractional-order planar autonomous linear system involving the Caputo-Fabrizio fractional derivative.
Bohui Yang   +4 more
doaj   +1 more source

Singularities at real points of ? space

open access: yesGeneral Relativity and Gravitation, 1980
In the presence of gravitational radiation, there are ordinarily no shear-free slices of null infinity. A four-complex-dimensional set of shear-free slices of complexified null infinity do exist. They comprise the manifold ℋ space. In general, there are no preferred real subspaces ofℋ space associated with slices of real null infinity.
Tod, K, Winicour, J
openaire   +2 more sources

The topology associated to cusp singular points [PDF]

open access: yes, 2012
In this paper we investigate the global geometry associated with cusp singular points of two-degree of freedom completely integrable systems. It typically happens that such singular points appear in couples, connected by a curve of hyperbolic singular ...
Konstantinos Efstathiou   +2 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Mathematical modeling of the process of nonlinear deformation of thin-walled structures

open access: yesВестник Дагестанского государственного технического университета: Технические науки
Objective. The objective is to develop a unified method for solving a general nonlinear boundary value problem associated with discontinuous phenomena, which allows identifying all the characteristic features of the behavior of thin-walled systems under ...
G. M. Murtazaliev, M. M. Paizulaev
doaj   +1 more source

Singular-point characterization in microscopic flows

open access: yesPhysical Review E, 2008
4 pages and 4 ...
Volpe, Giorgio   +2 more
openaire   +3 more sources

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