Results 81 to 90 of about 75,343 (266)
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Formation of a panoramic image of the inner surface of the pipe
Background. Visual non-destructive testing of the inner surface of pipes is an important aspect in their production and operation. A defect detected and corrected in a timely manner can significantly reduce the number of defects in production and prevent
Alexey S. Loshkarev
doaj +1 more source
Separatrices and singular points [PDF]
A new definition of separatrix is introduced and the theory developed is applied to the study of the topological structure of singular points. Each component of the complement of the separatrix set in a neighborhood of an isolated singular point is shown to satisfy one of seven types of behavior.
openaire +2 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
The work describes the construction, training and testing of an artificial neural network (ANN) designed for determining whether an arbitrary point a seven-dimensional projective complex spacebelongs to the variety of singular points of the first kind ...
Anatoliy Nicolaevich Makoha +1 more
doaj
How phagocytic cells kill bacteria: Lessons from a professional killer
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
PT-symmetric metasurfaces: wave manipulation and sensing using singular points
We investigate here active metasurfaces obeying parity–time (PT) symmetry and their sensing applications, taking advantage of singularities unique to non-Hermitian systems, such as the spontaneous PT-symmetry-breaking point (exceptional point or EP) and ...
Maryam Sakhdari +2 more
doaj +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source

