Results 41 to 50 of about 64,352 (312)
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
Asymptotic behavior of singular solutions to semilinear fractional elliptic equations
Electronic Journal of Differential Equations, 2014 In this article we study the asymptotic behavior of positive singular solutions to the equation $$ (-\Delta)^{\alpha} u+u^p=0\quad\text{in } \Omega\setminus\{0\}, $$ subject to the conditions $u=0$ in $\Omega^c$ and $\lim_{x\to0}u(x)=\infty ...
Guowei Lin, Xiongjun Zheng
doaj
Singularity of solutions to singular SPDEs
Building on the notes [Hai17], we give a sufficient condition for the marginal distribution of the solution of singular SPDEs on the $d$-dimensional torus to be singular with respect to the law of the Gaussian measure induced by the linearised equation.
Hairer, Martin +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Sweeping algebraic curves for singular solutions [PDF]
Journal of Computational and Applied Mathematics, 2010 Many problems give rise to polynomial systems. These systems often have several parameters and we are interested to study how the solutions vary when we change the values for the parameters. Using predictor-corrector methods we track the solution paths. A point along a solution path is critical when the Jacobian matrix is rank deficient.
Kathy Piret, Jan Verschelde
openaire +2 more sources
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Positive decreasing solutions of systems of second order singular differential equations
Journal of Inequalities and Applications, 2000 Singular differential systems of the type are considered in an interval , where , , , are positive constants and , , , are positive continuous functions on .
Kusano Takaŝi, Tanigawa Tomoyuki
doaj
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
A novel method for nonlinear singular oscillators
Journal of Low Frequency Noise, Vibration and Active Control, 2021 The present work deals with a study of a nonlinear singular oscillator. To approximate the frequency–amplitude relationship of the singular oscillator, reproducing kernel method is employed. The approximate solution is compared with the exact solution as
Ali Akgül +3 more
doaj +1 more source