Results 51 to 60 of about 58,847 (264)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
The Singularities of the Solutions of the Cauchy Problem
Publications of the Research Institute for Mathematical Sciences, 1969 This paper is concerned with the Cauchy problem of linear partial differential equation with holomorphic coefficients in complex domain. The Cauchy-Kowalewski theorem asserts that locally there exists a unique holomorphic solution of the Cauchy problem provided that the initial surface is non-character istic and the initial data are holomorphic.
openaire +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Sweeping algebraic curves for singular solutions
Journal of Computational and Applied Mathematics, 2010 Many problems give rise to polynomial systems. These systems often have several parameters and we are interested to study how the solutions vary when we change the values for the parameters. Using predictor-corrector methods we track the solution paths. A point along a solution path is critical when the Jacobian matrix is rank deficient.
Kathy Piret, Jan Verschelde
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International Journal of Mathematics and Mathematical Sciences, 1988 In the present report, we investigate the formulation, for the numerical evaluation of the multidimensional singular integrals and integral equations, used in the theory of linear viscoelasticity. Some simple formulas are given for the numerical solution
E. G. Ladopoulos
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A novel method for nonlinear singular oscillators
Journal of Low Frequency Noise, Vibration and Active Control, 2021 The present work deals with a study of a nonlinear singular oscillator. To approximate the frequency–amplitude relationship of the singular oscillator, reproducing kernel method is employed. The approximate solution is compared with the exact solution as
Ali Akgül +3 more
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Electronic Journal of Differential Equations, 2016 We prove the existence and uniqueness of singular solutions (fundamental solution, very singular solution, and large solution) of quasilinear parabolic equations with absorption for Dirichlet boundary condition. We also show the short time behavior of
Nguyen Anh Dao
doaj
Minimal Solution of Singular LR Fuzzy Linear Systems
The Scientific World Journal, 2014 In this paper, the singular LR fuzzy linear system is introduced. Such systems are divided into two parts: singular consistent LR fuzzy linear systems and singular inconsistent LR fuzzy linear systems.
M. Nikuie, M. Z. Ahmad
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Singularity Analysis for the Existing Closed-Form Solutions of the Hand-Eye Calibration
IEEE Access, 2018 In this paper, a class of singular phenomenon is first found for the existing closed-form solutions of the hand-eye calibration problem with the form AiX = XBi when the angles corresponding to rotational parts of Ai and Bi are near or equal to π ...
Huajian Song +3 more
doaj +1 more source