Results 81 to 90 of about 56,216 (265)
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Multiple Solutions of Singular Perturbation Problems [PDF]
SIAM Journal on Mathematical Analysis, 1972 Under certain conditions on $g(x,u)$ we establish the existence and asymptotic behavior for small $\varepsilon > 0$ of multiple asymptotic solutions of the nonlinear boundary value problem \[ \begin{gathered} \varepsilon u'' + u' - g(x,u) = 0,\quad 0 0, \hfill \\ u'(1) + bu(1) = B > 0,\quad b > 0.
openaire +3 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Existence of regular and singular bound state solutions to a quasilinear equation
Boundary Value ProblemsThe existence of regular and singular bound state solutions to △ p u + f ( u ) = 0 , r ∈ R n ∖ { 0 } $$ \triangle _{p}u+f(u)=0,~~~r\in \mathbb{R}^{n}\backslash \{0\} $$ is considered. Our result concerns the solution according to its behavior as r → 0 $r\
Wei-Chuan Wang
doaj +1 more source
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
A Progress Report on Numerical Solutions of Least Squares Adjustment in GNU Project Gama
Acta Polytechnica, 2005 GNU project Gama for adjustment of geodetic networks is presented. Numerical solution of Least Squares Adjustment in the project is based on Singular Value Decomposition (SVD) and General Orthogonalization Algorithm (GSO). Both algorithms enable solution
A. Čepek, J. Pytel
doaj
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
The Generalized Wave Model Representation of Singular 2-D Systems
International Journal of Industrial Engineering and Production Research, 2007 M. and M. Abstract: Existence and uniqueness of solution for singular 2-D systems depends on regularity condition. Simple regularity implies regularity and under this assumption, the generalized wave model (GWM) is introduced to cast singular 2-D ...
M. Haji-Ramazanali, M. Shafiee
doaj
Journal of Taibah University for ScienceThis manuscript investigates a fractional piecewise dengue transmission model using singular and non-singular kernels. The existence results and uniqueness of the solution are established by using the approach of fixed point and in the framework of ...
Mati ur Rahman +4 more
doaj +1 more source