Results 81 to 90 of about 65,657 (313)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

An efficient spectral method for nonlinear Volterra integro-differential equations with weakly singular kernels

open access: yesMathematical Modelling and Analysis
For Volterra integro-differential equations (VIDEs) with weakly singular kernels, their solutions are singular at the initial time. This property brings a great challenge to traditional numerical methods. Here, we investigate the numerical approximation
ZhiPeng Liu, DongYa Tao, Chao Zhang
doaj   +1 more source

The Periodic Solutions of the Compound Singular Fractional Differential System with Delay

open access: yesInternational Journal of Differential Equations, 2010
The paper gives sufficient conditions on the existence of periodic solution for a class of compound singular fractional differential systems with delay, involving Nishimoto fractional derivative.
XuTing Wei, XuanZhu Lu
doaj   +1 more source

Application of the Brouwer and the Kakutani fixed-point theorems to a discrete equation with a double singular structure

open access: yesFixed Point Theory and Applications, 2018
Applying the method consisting of a combination of the Brouwer and the Kakutani fixed-point theorems to a discrete equation with a double singular structure, that is, to a discrete singular equation of which the denominator contains another discrete ...
Minoru Tabata, Nobuoki Eshima
doaj   +1 more source

Singular Solutions to a (3 + 1)-D Protter-Morawetz Problem for Keldysh-Type Equations [PDF]

open access: gold, 2017
Nedyu Popivanov   +3 more
openalex   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Altered Dynamic Functional Network Connectivity in Post‐Stroke Aphasia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Previous studies examining post‐stroke aphasia (PSA) patients via resting‐state functional magnetic resonance imaging (rs‐fMRI) have predominantly focused on static functional connectivity. In contrast, the current investigation aims to elucidate the alterations in dynamic functional network connectivity (dFNC) among PSA patients ...
Guihua Xu   +6 more
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

The Singularity of Kontsevich?s Solution for QH*(CP2) [PDF]

open access: yesMathematical Physics, Analysis and Geometry, 2005
We study the singularity of the Kontsevich's solution of the WDVV equations of associativity. We prove that it corresponds to a singularity in the change of two coordinates systems of the Frobenius manifold given by the quantum cohomology of $CP^2$.
openaire   +2 more sources

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