Results 51 to 60 of about 593,696 (329)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Известия высших учебных заведений. Поволжский регион: Физико-математические науки, 2020 Background. There is no problem in finding a general solution to the ordinary differential Clairaut equation. The corresponding procedure is described in details in the theory of ordinary differential equations.
L. A. Zhidova
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Singular solutions to the Seiberg-Witten and Freund equations on flat space from an iterative method
, 2006 Although it is well known that the Seiberg-Witten equations do not admit nontrivial $L^2$ solutions in flat space, singular solutions to them have been previously exhibited -- either in $R^3$ or in the dimensionally reduced spaces $R^2$ and $R^1 ...
Kustaanheimo P. +3 more
core +1 more source
Positive Solutions of Singular Integral Equations
Journal of Integral Equations and Applications, 2000 The nonlinear singular integral equation \[ y(t)= h(t)+ \int^T_0 K(t,s)f \bigl(y(s)\bigr)ds,\;t\in\langle 0,T\rangle,\;T\in(0,+ \infty \rangle \] is considered. The Schauder fixed point theorem \((T< \infty)\) and the Schauder-Tikhonov fixed point theorem \((T=+ \infty)\) are used to establish the existence of continuous, positive solution of the ...
Meehan, Maria, O'Regan, Donal
openaire +3 more sources
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Solutions of some Monge-Amp\`ere equations with isolated and line singularities [PDF]
, 2013 In this paper, we study existence, regularity, classification, and asymptotical behaviors of solutions of some Monge-Amp\`ere equations with isolated and line singularities.
Jin, Tianling, Xiong, Jingang
core
Renormalization schemes for SFT solutions
, 2014 In this paper, we examine the space of renormalization schemes compatible with the Kiermaier and Okawa [arXiv:0707.4472] framework for constructing Open String Field Theory solutions based on marginal operators with singular self-OPEs.
Karczmarek, Joanna L., Longton, Matheson
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source