Results 51 to 60 of about 76,645 (265)

Multiplicity of Positive Solutions for a Singular Tempered Fractional Initial-Boundary Value Problem with Changing-Sign Perturbation Term

open access: yesFractal and Fractional
In this paper, we focus on the multiplicity of positive solutions for a singular tempered fractional initial-boundary value problem with a p-Laplacian operator and a changing-sign perturbation term.
Xinguang Zhang   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Elliptic perturbations for Hammerstein equations with singular nonlinear term

open access: yesElectronic Journal of Differential Equations, 2006
We consider a singular elliptic perturbation of a Hammerstein integral equation with singular nonlinear term at the origin. The compactness of the solutions to the perturbed problem and, hence, the existence of a positive solution for the ...
Giuseppe Maria Coclite   +1 more
doaj  

Positive Solution of Singular Fractional Differential Equation in Banach Space

open access: yesJournal of Applied Mathematics, 2011
We investigated a singular multipoint boundary value problem for fractional differential equation in Banach space. The nonlinear term 𝑓(𝑡,𝑥,𝑦) is positive and singular at 𝑥=𝜃 and (or) 𝑦=𝜃.
Jianxin Cao, Haibo Chen
doaj   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Pointwise Gradient Estimates in Multi-dimensional Slow Diffusion Equations with a Singular Quenching Term

open access: yesAdvanced Nonlinear Studies, 2020
We consider the high-dimensional equation ∂t⁡u-Δ⁢um+u-β⁢χ{u>0}=0{\partial_{t}u-\Delta u^{m}+u^{-\beta}{\chi_{\{u>0\}}}=0}, extending the mathematical treatment made in 1992 by B. Kawohl and R. Kersner for the one-dimensional case.
Dao Nguyen Anh   +2 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Multiple solutions to a singular Lane-Emden-Fowler equation with convection term

open access: yesElectronic Journal of Differential Equations, 2008
This article concerns the existence of multiple solutions for the problem $$displaylines{ -Delta u = K(x)u^{-alpha}+s(mathcal{A}u^eta+mathcal{B} | abla u|^zeta)+f(x) quad hbox{in }Omegacr u > 0 quad hbox{in }Omegacr u = 0 quad ...
Enrique Lami Dozo, Carlos C. Aranda
doaj  

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Positive Solutions for Second-Order Singular Semipositone Differential Equations Involving Stieltjes Integral Conditions

open access: yesAbstract and Applied Analysis, 2012
By means of the fixed point theory in cones, we investigate the existence of positive solutions for the following second-order singular differential equations with a negatively perturbed term: −u′′(t)=λ[f(t,u(t))−q(t ...
Jiqiang Jiang, Lishan Liu, Yonghong Wu
doaj   +1 more source

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