Results 111 to 120 of about 298,127 (271)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
On the existence of Levi Foliations
Anais da Academia Brasileira de Ciências, 2001 Let L be a real 3 dimensional analytic variety. For each regular point p L there exists a unique complex line l p on the space tangent to L at p. When the field of complex line p l p is completely integrable, we say that L is Levi variety.
RENATA N. OSTWALD
doaj +1 more source
The Singular World of Singular Cardinals [PDF]
, 2015 To appear in Logic Without Borders: Essays on Set Theory, Model Theory, Philosophical Logic and Philosophy of Mathematics Edited by \AA sa Hirvonen, Juha Kontinen, Roman Kossak and Andr\'es ...
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Sudden future singularities [PDF]
Classical and Quantum Gravity, 2004 We show that a singularity can occur at a finite future time in an expanding Friedmann universe even when the density is positive and the density plus the sum of the principal pressures is positive. Explicit examples are constructed and a simple condition is given which can be used to eliminate behaviour of this sort if it is judged to be unphysical.
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Tubular surface generated by a curve lying on a regular surface and its characterizations
AIMS MathematicsIn this research, we have constructed and studied special tubular surfaces in Euclidean 3-space $ \mathbb{R}^{3} $. We examined the singularities and geometrical properties of these surfaces.
A. A. Abdel-Salam +2 more
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Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Painleve's determinateness theorem extended to proper coverings
Electronic Journal of Differential Equations, 2010 We extend Painleve's determinateness theorem to first-order ordinary differential equations in the complex domain, with known terms allowed be multivalued in the dependent variable. The multivaluedness is supposed to be resolved by proper coverings.
Claudi Meneghin
doaj
Singular Reference Without Singular Thought [PDF]
Manuscrito, 2016 Abstract In this paper I challenge the widespread assumption that the conditions for singular reference are more or less the same as the conditions for singular thought. I claim that we refer singularly to things without thinking singularly about them more often than it is usually believed.
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