Results 111 to 120 of about 1,311,541 (283)

Potential effects of intrinsic heart pacemaker cell mechanisms on dysrhythmic cardiac action potential firing

open access: yesFrontiers in Physiology, 2015
The heart’s regular electrical activity is initiated by specialized cardiac pacemaker cells residing in the sinoatrial node. The rate and rhythm of spontaneous action potential firing of sinoatrial node cells are regulated by stochastic mechanisms that ...
Yael eYaniv   +2 more
doaj   +1 more source

Slow invariant manifold of heartbeat model [PDF]

open access: yes, 2014
A new approach called Flow Curvature Method has been recently developed in a book entitled Differential Geometry Applied to Dynamical Systems. It consists in considering the trajectory curve, integral of any n-dimensional dynamical system as a curve in ...
Ginoux, Jean-Marc, Rossetto, Bruno
core  

Heart [PDF]

open access: yes, 2008
Histology blog entry for October 6, 2008 about the ...
Krause, William J., II, 1942-
core   +1 more source

Synchronization of Pacemaking in the Sinoatrial Node: A Mathematical Modeling Study

open access: yesFrontiers of Physics, 2018
Computational studies using mathematical models of the sinoatrial node (SAN) cardiac action potential (AP) have provided important insight into the fundamental nature of cell excitability, cardiac arrhythmias, and potential therapies. While the impact of
Daniel H. Gratz   +3 more
semanticscholar   +1 more source

Models of cardiomyocyte–non‐myocyte electrical interactions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Cardiomyocyte–non‐myocyte (CM–NM) electrotonic coupling. Left: conceptual contact‐based interactions between CM and other NM via connexin (Cx) proteins. Three basic scenarios are proposed: (i) ‘zero‐sided coupling’ where there are no electrical connections between CM and NM, (ii) ‘single‐sided coupling’ where NM are connected to ...
Ana Simon‐Chica   +2 more
wiley   +1 more source

Do human sinoatrial node cells have t-tubules?

open access: yesTranslational Research in Anatomy, 2021
Every heartbeat is generated by spontaneously depolarizing specialised nodal cells that make up the sinoatrial node (SN). The SN's unique properties depend on two complex mechanisms - the membrane-voltage and the Ca2+ clocks, regulated by strictly ...
Maria A. Petkova, Halina Dobrzynski
doaj  

Influence of autonomic nervous system in the inducibility of atrial fibrillation. [PDF]

open access: yes, 2008
Cílem této práce je zjištění změn předcházejícím fibrilaci síní. Pozorována je rovnováha mezi sympatikem a parasympatikem. Do experimentu výzkumného ústavu Cleavlendské kliniky bylo zapojeno šest psů různých ras.
Šrutová, Martina
core  

The early stages of heart development: insights from chicken embryos [PDF]

open access: yes, 2016
The heart is the first functioning organ in the developing embryo and the detailed understanding of the molecular and cellular mechanisms involved in its formation provides insights into congenital malformations affecting its function and therefore the ...
Alsan   +19 more
core   +2 more sources

Pregnancy and oestrogen regulate sinoatrial node calcium homeostasis and accelerate pacemaking

open access: yesCardiovascular Research, 2018
Aims During pregnancy, there is a significant increase in heart rate (HR) potentially associated with an increased risk of arrhythmias or exacerbation of pre-existing cardiac conditions endangering both mother and foetus.
Nabil El Khoury   +5 more
semanticscholar   +1 more source

Gap junctional and ephaptic coupling in cardiac electrical propagation: homocellular and heterocellular perspectives

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Intricate cellular electrical coupling networks in the heart. Various cell types couple the central cardiomyocyte through gap junctional contacts, with the exception of neurons. Whether ephaptic coupling (EpC) occurs in homocellular or heterocellular contexts beyond cardiomyocyte–cardiomyocyte interactions remains unclear ...
Xiaobo Wu   +2 more
wiley   +1 more source

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