ABSTRACT Objective This study aimed to investigate the potential role of cesium chloride (CsCl), ivabradine (IVA), and isoproterenol (ISO) on the sensory transmission of bladder afferents to graded urinary bladder distension (UBD). We specifically selected these drugs to target the hyperpolarization‐activated cyclic nucleotide‐gated (HCN) cation ...
Eric Woon+5 more
wiley +1 more source
Artificial biological pacemakers were developed and tested in canine ventricles. Next steps will require obtaining oscillations sensitive to external regulations, and robust with respect to long term drifts of expression levels of pacemaker currents and ...
Kanani, Sandra+2 more
core
Quantitative study of ageing changes in the human sinoatrial node and internodal tracts. [PDF]
Michael J. Davies, Ariela Pomerance
openalex +1 more source
Sinus node recovery time and calculated sinoatrial conduction time in normal subjects and patients with sinus node dysfunction. [PDF]
G. Breithardt, L Seipel, F Loogen
openalex +1 more source
Should socioeconomic factors be considered as traditional risk factors for cardiovascular disease, as confounders, or as risk modifiers? [PDF]
A large number of studies show that cardiovascular disease and its traditional risk factors are associated with socioeconomic conditions. However, their etiological role in the development of cardiovascular outcomes is not always well understood ...
De Vogli, R., Marmot, M.
core
"Fade" of hyperpolarizing responses to vagal stimulation at the sinoatrial and atrioventricular nodes of the rabbit heart. [PDF]
Joseph J. Salata, José Jalife
openalex +1 more source
Introduction to the Phasic Effects of the Vagus on Sinoatrial and Atrioventricular Nodes [PDF]
I want to emphasize that the vagus has effects upon both the sinus node and the A-V node. It slows sinus discharge, and it depresses, delays, or blocks atrioventricular transmission.
Moe, Gordon
core +1 more source
Inhibitory actions of ZENECA ZD7288 on whole‐cell hyperpolarization activated inward current (If) in guinea‐pig dissociated sinoatrial node cells [PDF]
R. E. BoSmith+2 more
openalex +1 more source
Hippo Signaling: Advances in Potential Therapeutic Targets for Sinoatrial Node Disorders. [PDF]
Quinn JN, Wang J.
europepmc +1 more source