Results 111 to 120 of about 1,321,275 (276)

Pharmacological Targeting of Hyperpolarization‐Activated Cyclic Nucleotide‐Gated Cation Channels on Bladder Afferent Sensory Transmission

open access: yesLUTS: Lower Urinary Tract Symptoms, Volume 17, Issue 5, September 2025.
ABSTRACT Objective This study aimed to investigate the potential role of cesium chloride (CsCl), ivabradine (IVA), and isoproterenol (ISO) on the sensory transmission of bladder afferents to graded urinary bladder distension (UBD). We specifically selected these drugs to target the hyperpolarization‐activated cyclic nucleotide‐gated (HCN) cation ...
Eric Woon   +5 more
wiley   +1 more source

Genetically engineered cardiac pacemaker: stem cells transfected with HCN2 gene and myocytes - a model

open access: yes, 2005
Artificial biological pacemakers were developed and tested in canine ventricles. Next steps will require obtaining oscillations sensitive to external regulations, and robust with respect to long term drifts of expression levels of pacemaker currents and ...
Kanani, Sandra   +2 more
core  

Should socioeconomic factors be considered as traditional risk factors for cardiovascular disease, as confounders, or as risk modifiers? [PDF]

open access: yes, 2008
A large number of studies show that cardiovascular disease and its traditional risk factors are associated with socioeconomic conditions. However, their etiological role in the development of cardiovascular outcomes is not always well understood ...
De Vogli, R., Marmot, M.
core  

Introduction to the Phasic Effects of the Vagus on Sinoatrial and Atrioventricular Nodes [PDF]

open access: yes, 1973
I want to emphasize that the vagus has effects upon both the sinus node and the A-V node. It slows sinus discharge, and it depresses, delays, or blocks atrioventricular transmission.
Moe, Gordon
core   +1 more source

Anesthetizing the Fibrillating Heart. [PDF]

open access: yes, 2019
See Article Lee et ...
Hanna, Peter   +3 more
core  

Home - About - Disclaimer - Privacy