Results 91 to 100 of about 12,234 (213)

A Case Report of PR Interval Prolongation Caused by Amlodipine

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Amlodipine is a widely used dihydropyridine calcium channel blocker. Its effects on the cardiac conduction system, especially PR interval prolongation, are rare but clinically important. We report a 25‐year‐old healthy male subject in a clinical trial with baseline first‐degree atrioventricular block (PR interval 230 ms).
Zhiying Fu, Suping Ling, Xiaoli Ji, He Zhu   +3 more
wiley   +1 more source

Comparative study of sinoatrial node morphology and innervation

, 2016
[...]. Aim of and objectives of the study. The aim of the study: to identify limits and innervation of the sinoatrial node in hearts of mice, rabbits and pigs. Objectives: 1. To examine the distribution of pacemaker cells within the right atrium. 2.
Inokaitis, Hermanas
core  

Irrigación del nodo sinoatrial en población colombiana [PDF]

, 2011
Antecedentes: El conocimiento exacto de la integración anatomofisiológica del sistema de conducción del corazón, es fundamental para la comprensión fisiopatológica, el diagnóstico y el manejo de muchas de las complicaciones de la enfermedad coronaria y ...
Quijano Blanco, Yobany
core  

Familial p.(Ala73Thr) Variant in GNB2 Associated With Mild Neurodevelopmental Features and Pilocytic Astrocytoma

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Pathogenic variants in GNB2 have been associated with a neurodevelopmental disorder that includes global developmental delays and intellectual disability, hypotonia, increased risk for seizures, heart and renal anomalies, and characteristic facial features.
Megan Glassford, Caroline Jennings, Anne Slavotinek   +2 more
wiley   +1 more source

Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria

, 2007
The sinoatrial node initiates the heartbeat and controls the rate and rhythm of contraction, thus serving as the pacemaker of the heart. Despite the crucial role of the sinoatrial node in heart function, the mechanisms that underlie its specification and
Wong, L. Y. Elaine, Christoffels, Vincent M., V. Wakker, D. E. Clout, Barnett, Phil, Hoogaars, Willem M. H., Ravesloot, Jan Hindrik, Clout, Danielle E., L.Y. E. Wong, Moorman, Antoon F. M., W. M.H. Hoogaars, Verkerk, Arie O., Engel, Angela, A. O. Verkerk, M. L. Bakker, P. Barnett, V. M. Christoffels, Verheijck, E. Etienne, Wakker, Vincent, E. E. Verheijck, A. F.M. Moorman, de Lange, Frederik J., A. Engel, Brons, Janynke F., J. F. Brons, Bakker, Martijn L., J. H. Ravesloot, F. J. de Lange   +27 more
core   +1 more source

Patient‐Specific In Silico Prediction of Outcomes of Partial Continuous‐Flow LVAD Treatment in Peripartum Cardiomyopathy

International Journal for Numerical Methods in Biomedical Engineering, Volume 42, Issue 6, June 2026.
Partial continuous‐flow left ventricular assist device (LVAD) treatment of peripartum cardiomyopathy provides greater functional improvement for higher than lower disease severity. The left ventricle and LVAD jointly generate ventricular output for mild functional impairment, where the left ventricular contribution decreases with increasing LVAD ...
Juliet Nagawa, Kevin L. Sack, N. John Nchejane, Y. Dodzi Motchon, Mazin S. Sirry, Sarah Kraus, Neil H. Davies, Ntobeko A. B. Ntusi, Thomas Franz   +8 more
wiley   +1 more source

A protective role of Nox1/NADPH oxidase in a mouse model with hypoxia-induced bradycardia

Journal of Pharmacological Sciences, 2015
Although it has been reported that endotoxin-induced expression of Nox1 in the heart contributes to apoptosis in cardiomyocytes, functional role of Nox1 at the physiological expression level has not been elucidated.
Akiteru Kojima, Akio Matsumoto, Hirofumi Nishida, Yoshie Reien, Kazumi Iwata, Takeshi Shirayama, Chihiro Yabe-Nishimura, Haruaki Nakaya   +7 more
doaj   +1 more source

Sleep Apnea and Paroxysmal Atrial Fibrillation: Diurnal Patterning of Autonomic Dysfunction and Influence of CPAP Therapy

Journal of Arrhythmia, Volume 42, Issue 3, June 2026.
Autonomic dysfunction in sleep apnea shows diurnal variation, with stronger associations between SDB severity and HRV during wakefulness than sleep. CPAP therapy induces complex, state‐dependent changes in HRV, suggesting that daytime autonomic alterations may better reflect sustained cardiovascular risk in patients with paroxysmal atrial fibrillation.
Sepideh Khazaie, Lu Wang, Farhad Kaffashi, Ahana Sandhu, Mina K. Chung, Catherine M. Heinzinger, David R. Van Wagoner, Kenneth A. Loparo, Harneet K. Walia, James F. Bena, Reena Mehra   +10 more
wiley   +1 more source

Affect and conceptual learning in indoor and green outdoor school environments: Psychophysiological self‐regulation matters

British Journal of Educational Psychology, Volume 96, Issue 2, Page 802-820, June 2026.
Abstract Background Research on the role of the physical school environment in areas other than educational psychology has documented the benefits of exposure to nature for cognitive and emotional functioning. Positive effects have been indicated not only after a break in nature in mentally fatigued students but also in students who did not have ...
Lucia Mason, Libera Y. Mastromatteo, Cecilia Rocchi, Sara Scrimin   +3 more
wiley   +1 more source

Transcriptome analysis of mouse and human sinoatrial node cells reveals a conserved genetic program

, 2019
The rate of contraction of the heart relies on proper development and function of the sinoatrial node, which consists of a small heterogeneous cell population, including Tbx3+ pacemaker cells. Here, we have isolated and characterized the Tbx3+ cells from
Boukens, Bas J., Christoffels, Vincent M., Eif, Vincent W. W.,, Bakker, Martijn, Wakker, Vincent, Zaffran, Stéphane, de Gier-de Vries, Corrie, Duijvenboden, Karel, Van, Gier-de Vries, Corrie,, Gier-de Vries, Corrie, De, Stefanovic, Sonia, van Duijvenboden, Karel, Duijvenboden, Karel,, van Eif, Vincent W. W., Eif, Vincent W. W., Van, Verkerk, Arie O.   +15 more
core   +1 more source