Results 81 to 90 of about 12,234 (213)

Análise comparativa entre a vascularização arterial ventricular e do nó sinoatrial em corações de cães Comparative analysis between both ventricular and sinoatrial node arterial vascularization in heart of dogs

Pesquisa Veterinária Brasileira, 2013
Utilizamos nesta pesquisa 40 corações de cães adultos, machos e fêmeas, de idades variadas, que não portavam nenhuma afecção cardíaca. Os corações tiveram as artérias coronárias injetadas, separadamente, com Neoprene Látex 450, corado com pigmento ...
Caio Biasi, Vicente Borelli, Rodrigo F. Prazeres, Phelipe O. Favaron, Valdir Pavanelo Junior, Thiago P.A. Aloia, Pedro P. Bombonato   +6 more
doaj  

An age‐associated decline in the role of the sarcoplasmic reticulum and associated calcium‐handling proteins sets the pace for sinoatrial node function

The Journal of Physiology, EarlyView.
Abstract figure legend Stable, responsive pacemaking in the sinoatrial node is driven by the activity of the funny current (membrane clock), interplay of calcium cycling and release from the sarcoendoplasmic reticulum with depolarising sodium‐calcium exchange current (calcium clock). With increasing age, key proteins associated with calcium cycling are
Sandra A. Jones, Fiona S. Godbeer, Matthew K. Lancaster   +2 more
wiley   +1 more source

Immunocytochemical Demonstration of the Equilibrative Nucleoside Transporter rENT1 in Rat Sinoatrial Node

, 2002
Adenosine exerts multiple receptor-mediated effects in the heart, including a negative chronotropic effect on the sinoatrial node. The aim of this study was to investigate the distribution of the equilibrative nucleoside transporter rENT1 in rat ...
C.E. Cass, M.R. Boyett, H. Musa, S.A. Baldwin, H. Dobrzynski, F. Abidi, J.D. Young, Z. Berry   +7 more
core   +1 more source

TRIP8bnano peptide prevents cAMP binding to HCN2 channels alleviating pain‐like behaviors in rats with neuropathic pain

The Journal of Physiology, EarlyView.
Abstract figure legend We tested the hypothesis that cAMP binding to HCN2 channels in nociceptors is a causal driver of neuropathic pain by using TRIP8bnano, a synthetic peptide we previously developed as a selective antagonist of cAMP in HCN channels. TRIP8bnano effectively abolishes cAMP potentiation of HCN2 currents in small‐diameter DRG neurons and
Santiago I. Loya‐Lopez, Kimberly Gomez, Alessandro Porro, Gerhard Thiel, Anna Moroni, Heather N. Allen, Rajesh Khanna, Andrea Saponaro   +7 more
wiley   +1 more source

HL-1 cells express an inwardly rectifying K+ current activated via muscarinic receptors comparable to that in mouse atrial myocytes

, 2010
An inwardly rectifying K^+ current is present in atrial cardiac myocytes that is activated by acetylcholine (I_{KACh}). Physiologically, activation of the current in the SA node is important in slowing the heart rate with increased parasympathetic tone ...
Muriel Nobles, Sonia Sebastian, Tinker, A., Andrew Tinker, Nobles, M., Sebastian, S., Nobles, Muriel   +6 more
core   +1 more source

Use of machine learning and Poincaré density grid in the diagnosis of sinus node dysfunction caused by sinoatrial conduction block in dogs

Journal of Veterinary Internal Medicine
Background Sinus node dysfunction because of abnormal impulse generation or sinoatrial conduction block causes bradycardia that can be difficult to differentiate from high parasympathetic/low sympathetic modulation (HP/LSM).
Wyatt Hutson Flanders, N. Sydney Moïse, Niels F. Otani   +2 more
doaj   +1 more source

Potential effects of intrinsic heart pacemaker cell mechanisms on dysrhythmic cardiac action potential firing

Frontiers in Physiology, 2015
The heart’s regular electrical activity is initiated by specialized cardiac pacemaker cells residing in the sinoatrial node. The rate and rhythm of spontaneous action potential firing of sinoatrial node cells are regulated by stochastic mechanisms that ...
Yael eYaniv, Kenta eTsutsui, Edward eLakatta   +2 more
doaj   +1 more source

An Accessible Algorithm for the Quick and Precise Interpretation of Atrioventricular Blocks in Electrocardiograms

Annals of Noninvasive Electrocardiology, Volume 31, Issue 4, July 2026.
Interpretation of electrocardiograms (ECGs) using an algorithm can improve the detection and diagnosis of atrioventricular blocks in clinical practice. The proposed algorithm, with its high accuracy and structured approach, can help both experienced and less‐experienced healthcare professionals interpret ECGs with more precision, leading to early ...
Ali A. Ashkanani, Ali H. Ashkanani, Mohammad F. Alkandari, Malak A. Ashkanani, Maraheb M. Alkhalidi   +4 more
wiley   +1 more source

Human sinoatrial node detailed electrophysiology model and human sinoatrial node Resonant model responses to perturbation in an ion transport pathway.

, 2019
A: Action potential waveforms simulated in human sinoatrial node cell electrophysiology model. B: Action potential waveforms simulated in human sinoatrial resonant model under control conditions (CTRL) (dark black solid line) and upon 10% (dotted line ...
Partha S. Roop (6725684), Nitish D. Patel (6725678), Avinash Malik (6725681), Sucheta Sehgal (6725675), Mark L. Trew (6725687)   +4 more
core   +1 more source

Self-administered intranasal etripamil: a breakthrough in PSVT first-line treatment

Global Cardiology
Dear Editor,  PSVT, AVRT, and AVNRT are types of arrhythmia resulting from disruptions in the heart's electrical activity, originating from the sinoatrial node and propagating via the atria to the AV node, causing sudden symptoms like palpitations ...
Muddassir Khalid, Aqsa Asif, Sara Rasheed   +2 more
doaj   +1 more source