Results 81 to 90 of about 10,333 (179)

Parasympathetic Tone Selectively Modulates Electrogram Fragmentation and Spectral Properties in Right Atrial Ganglionated Plexi

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
Electrogram fragmentation and spectral EGMs features in GPs area are selectively modulated by parasympathetic tone, as demonstrated by high‐density right atrial mapping before and after vagal blockade. EGMs, bipolar atrial electrograms; GPs, ganglionated plexi; RA, right atrium.
Andrea Giomi, Andrea Bernardini, Alessandro Paoletti Perini, Margherita Padeletti, Cristiano Salvatore Zaccaria, Federica Michelotti, Umberto Signorini, Rossella Marcucci, Massimo Milli   +8 more
wiley   +1 more source

Análise comparativa entre a vascularização arterial ventricular e do nó sinoatrial em corações de cães Comparative analysis between both ventricular and sinoatrial node arterial vascularization in heart of dogs

Pesquisa Veterinária Brasileira, 2013
Utilizamos nesta pesquisa 40 corações de cães adultos, machos e fêmeas, de idades variadas, que não portavam nenhuma afecção cardíaca. Os corações tiveram as artérias coronárias injetadas, separadamente, com Neoprene Látex 450, corado com pigmento ...
Caio Biasi, Vicente Borelli, Rodrigo F. Prazeres, Phelipe O. Favaron, Valdir Pavanelo Junior, Thiago P.A. Aloia, Pedro P. Bombonato   +6 more
doaj  

Use of machine learning and Poincaré density grid in the diagnosis of sinus node dysfunction caused by sinoatrial conduction block in dogs

Journal of Veterinary Internal Medicine
Background Sinus node dysfunction because of abnormal impulse generation or sinoatrial conduction block causes bradycardia that can be difficult to differentiate from high parasympathetic/low sympathetic modulation (HP/LSM).
Wyatt Hutson Flanders, N. Sydney Moïse, Niels F. Otani   +2 more
doaj   +1 more source

Artificial Intelligence Techniques in Cardiac Neuromodulation: Mechanisms, Applications, and Pathways to Clinical Translation

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
Artificial intelligence could improve patient selection, stimulation control, and response monitoring in cardiac neuromodulation, yet direct clinical evidence remains scarce. We map available techniques onto these three challenges and argue that safe, adaptive closed‐loop control and established therapy efficacy are prerequisites for translation ...
Kshitiz Pandey, Pratik Pandey, Sushmita Khanal, Ashish Panday   +3 more
wiley   +1 more source

Self-administered intranasal etripamil: a breakthrough in PSVT first-line treatment

Global Cardiology
Dear Editor,  PSVT, AVRT, and AVNRT are types of arrhythmia resulting from disruptions in the heart's electrical activity, originating from the sinoatrial node and propagating via the atria to the AV node, causing sudden symptoms like palpitations ...
Muddassir Khalid, Aqsa Asif, Sara Rasheed   +2 more
doaj   +1 more source

Potential effects of intrinsic heart pacemaker cell mechanisms on dysrhythmic cardiac action potential firing

Frontiers in Physiology, 2015
The heart’s regular electrical activity is initiated by specialized cardiac pacemaker cells residing in the sinoatrial node. The rate and rhythm of spontaneous action potential firing of sinoatrial node cells are regulated by stochastic mechanisms that ...
Yael eYaniv, Kenta eTsutsui, Edward eLakatta   +2 more
doaj   +1 more source

The GLP‐1–Mitochondria Axis in Metabolic Aging

Aging Cell, Volume 25, Issue 8, August 2026.
Glucagon‐like peptide‐1 receptor agonists engage AMPK–PGC‐1α signaling to remodel mitochondrial biogenesis, dynamics, and quality control, but downstream effects are context‐dependent and tissue‐specific rather than uniformly receptor‐proximal. Whether this proposed mitochondria‐incretin axis reflects a novel geroscience mechanism or indirect metabolic
Renin Chang, Andy P. Tsai, Boyang Wang, Chia‐Jung Li   +3 more
wiley   +1 more source

Aerobic Endurance Training Modulates Cardiac Renin‐Angiotensin System Peptides and Matrix Metalloproteinase Activity During Chronic Stress

Journal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT To investigate the involvement of metalloproteinases (MMPs) in the context of endurance training and their interactions with renin‐angiotensin signalling (RAS) in stress‐induced pathophysiological responses. Trained rats were submitted to 8‐weeks of endurance treadmill training with chronic mild stress (CMS), TS rats, and without CMS (T).
Vinicius Guzzoni, Fabiana Gomes Ferreira, Lívia Bruni de Souza, Rebecca Salomão, Nicholas Kesler, Rodrigo Yokota, Nilsa Regina Damaceno‐Rodrigues, Elia Garcia Caldini, Fernanda Klein Marcondes, Rita de Cássia Marqueti, Steven T. Haller, David J. Kennedy, Lauren G. Koch, Dulce Elena Casarini, Tatiana Sousa Cunha   +14 more
wiley   +1 more source

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

The Journal of Physiology, Volume 604, Issue 16, Page 6619-6638, 15 August 2026.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

A protective role of Nox1/NADPH oxidase in a mouse model with hypoxia-induced bradycardia

Journal of Pharmacological Sciences, 2015
Although it has been reported that endotoxin-induced expression of Nox1 in the heart contributes to apoptosis in cardiomyocytes, functional role of Nox1 at the physiological expression level has not been elucidated.
Akiteru Kojima, Akio Matsumoto, Hirofumi Nishida, Yoshie Reien, Kazumi Iwata, Takeshi Shirayama, Chihiro Yabe-Nishimura, Haruaki Nakaya   +7 more
doaj   +1 more source