Results 111 to 120 of about 20,476 (227)
, 2008 peer reviewedIvabradine (Procoralan), a new If inhibitor which acts specifically and in a dose-dependent manner on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering agent.
LANCELLOTTI, Patrizio
core
Pacing and Clinical Electrophysiology, Volume 49, Issue 5, Page 636-643, May 2026.ABSTRACT Background Procedural and clinical outcomes in patients with obesity undergoing catheter ablation for atrial fibrillation (AF) have been mixed. Clinical data in the context of pulsed field ablation (PFA) are currently limited in this patient cohort.
Francis J. Ha +6 more
wiley +1 more source
The Journal of Physiology, Volume 604, Issue 9, Page 3504-3512, 1 May 2026.Abstract figure legend Cardiac pacemaking: the redundant and robust organ‐to‐subcellular system driving the spontaneous electrical activity responsible for regular, rhythmic excitation of the heart. Abstract The heart is an electrically controlled, mechanical pump that provides a constant supply of blood to the body.
Eilidh A. MacDonald, T. Alexander Quinn
wiley +1 more source
Transcriptional profile of the rat cardiovascular system at single-cell resolution
Cell ReportsSummary: We sought to characterize cellular composition across the cardiovascular system of the healthy Wistar rat, an important model in preclinical cardiovascular research.
Alessandro Arduini +16 more
doaj +1 more source
Citation: 'sinoatrial node' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11220 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Are physiological oscillations physiological?
The Journal of Physiology, Volume 604, Issue 9, Page 3672-3693, 1 May 2026.Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley +1 more source
Structure mirroring function: What's the ‘matter’ with the funny current?
The Journal of Physiology, Volume 604, Issue 9, Page 3513-3532, 1 May 2026.Abstract figure legend The ‘funny’ (If) current of cardiac pacemaker cells has been first identified in the late 1970s as a major mechanism in the generation and control of cardiac pacemaking. Decades of studies have since described the properties of the funny current and of its molecular components, HCN channels, in the heart and brain, providing the ...
Andrea Saponaro, Dario DiFrancesco
wiley +1 more source
Rhythm Generating Mechanisms in Rat Sinoatrial Node
Current Medical IssuesBackground: The major membrane currents responsible for sinoatrial (SA) rhythm generation are generally studied in isolated cardiac cells using electrophysiological tools. Such studies are resource and labor-intensive.
Jesi Charles +7 more
doaj +1 more source
Rare Case of Rapidly Worsening REM Sleep Induced Bradycardia
Case Reports in Cardiology, 2015 Sinoatrial arrest also known as sinus pause occurs when sinoatrial node of the heart transiently ceases to generate the electrical impulse necessary for the myocardium to contract. It may last from 2.0 seconds to several minutes. Etiologies of sinoatrial
Ayyappa S. Duba +6 more
doaj +1 more source
Simplified 2D Bidomain Model of Whole Heart Electrical Activity and ECG Generation
Measurement Science Review, 2014 The aim of this study was the development of a geometrically simple and highly computationally-efficient two dimensional (2D) biophysical model of whole heart electrical activity, incorporating spontaneous activation of the sinoatrial node (SAN), the ...
Sovilj Siniša +4 more
doaj +1 more source