Results 141 to 150 of about 22,194 (282)

Na/Ca exchange in the atrium: Role in sinoatrial node pacemaking and excitation-contraction coupling

, 2020
Xin Yue, Adina Hazan, Sabine Lotteau, Rui Zhang, Angelo G. Torrente, Kenneth D. Philipson, Michela Ottolia, Joshua I. Goldhaber   +7 more
openalex   +2 more sources

Innervation and Neuronal Control of the Mammalian Sinoatrial Node a Comprehensive Atlas [PDF]

, 2021
Peter Hanna, Michael J. Dacey, Jaclyn A. Brennan, Alison Moss, Shaina Robbins, Sirisha Achanta, Natália P. Biscola, Mohammed Amer Swid, Pradeep S. Rajendran, Shumpei Mori, Joseph Hadaya, Elizabeth Smith, Stanley G. Peirce, Jin Chen, Leif A. Havton, Zixi Cheng, Rajanikanth Vadigepalli, James S. Schwaber, Robert L. Lux, Igor R. Efimov, John D. Tompkins, Donald B. Hoover, Jeffrey L. Ardell, Kalyanam Shivkumar   +23 more
openalex   +1 more source

Physical exercise intervention in glycogen storage disease IIIa: Feasibility and multisystem benefits

Experimental Physiology, Volume 111, Issue 1, Page 153-166, 1 January 2026.
Abstract Glycogen storage disease III (GSD‐III) is caused by an inherited deficiency of the glycogen debranching enzyme. Affecting the liver, muscle and heart, GSD‐IIIa is the most common GSD‐III subtype. We evaluated the feasibility and safety of a physical exercise intervention in patients with GSD‐IIIa and its effects at the multisystem level.
Asunción Bustos‐Sellers, Almudena Montalvo‐Pérez, Araceli Boraita, Gonzalo Saco‐Ledo, Lidia B. Alejo, David Barranco‐Gil, Pedro L. Valenzuela, Nerea López‐Maldonado, Roser Ferrer‐Costa, Javier Esparcia‐Estrela, Celia Monteagudo‐López, Tomàs Pinós, Alejando Santos‐Lozano, Alejandro Lucia, Alfredo Santalla   +14 more
wiley   +1 more source

Upregulation of Adenosine A1 Receptors Facilitates Sinoatrial Node Dysfunction in Chronic Canine Heart Failure by Exacerbating Nodal Conduction Abnormalities Revealed by Novel Dual-Sided Intramural Optical Mapping [PDF]

, 2014
Qing Lou, Brian J. Hansen, Olga Fedorenko, Thomas A. Csepe, Anuradha Kalyanasundaram, Ning Li, Lori T. Hage, Alexey V. Glukhov, George E. Billman, Raul Weiss, Peter J. Mohler, Sándor Györke, Brandon J. Biesiadecki, Cynthia A. Carnes, Vadim V. Fedorov   +14 more
openalex   +1 more source

Genomic Structural Equation Modeling Combined With Post‐GWAS Analysis Identifies Two Risk Gene Loci and Functionally Sensitive Genes Associated With Cardiac Conduction Block

Genetics Research , Volume 2026, Issue 1, 2026.
Background Cardiac conduction disorders (CCDs) represent a broad spectrum of severe cardiovascular conditions associated with syncope and sudden cardiac death. Therefore, identification of reliable biomarkers is necessary to significantly improve the diagnostic accuracy and therapeutic outcomes of CCDs. This study analyzed GWAS summary datasets using a
Tongyu Wang, Xinge Miao, Yunlong Xia, Irfan Ahmad   +3 more
wiley   +1 more source

Research on the Side Effects of Intravenous Methylprednisolone in Hospitalized Pediatric Patients With Neurological Diseases

Journal of Clinical Pharmacy and Therapeutics, Volume 2026, Issue 1, 2026.
Background High‐dose methylprednisolone pulse therapy is being increasingly used in the treatment of neurological disorders; however, there is still a lack of studies on the side effects associated with this treatment regimen in the context of neurological diseases.
Baotian Wang, Shunxin Wang, Li Yang, Junhong Jiang, Ran Hua, Jiulai Tang, De Wu, Yue Xu   +7 more
wiley   +1 more source

Genetically engineered cardiac pacemaker: stem cells transfected with HCN2 gene and myocytes - a model

, 2005
Artificial biological pacemakers were developed and tested in canine ventricles. Next steps will require obtaining oscillations sensitive to external regulations, and robust with respect to long term drifts of expression levels of pacemaker currents and ...
Kanani, Sandra, Krinsky, Valentine, Pumir, Alain   +2 more
core  

Transforming Epilepsy Care: A Comprehensive Review of Technological Innovations, Artificial Intelligence Advancements, and Precision Tools for Enhanced Seizure Management and Patient Outcomes

Scientifica, Volume 2026, Issue 1, 2026.
Epilepsy is a neurological disorder characterized by repeated, unprovoked seizures arising from abnormal electrical activity in the brain. The management of epilepsy presents several significant challenges. One of these challenges involves drug resistance, where seizures persist despite treatment with multiple antiepileptic drugs, requiring a tailored ...
Mukul Shyam, Naincy Kaushal, Manish Yadav, Prathap Srirangan, Sabina Evan Prince, Nidhi Chaudhary   +5 more
wiley   +1 more source

Slow invariant manifold of heartbeat model [PDF]

, 2014
A new approach called Flow Curvature Method has been recently developed in a book entitled Differential Geometry Applied to Dynamical Systems. It consists in considering the trajectory curve, integral of any n-dimensional dynamical system as a curve in ...
Ginoux, Jean-Marc, Rossetto, Bruno
core  

The Heart’s Pacemaker Mimics Brain Cytoarchitecture and Function: Autonomic innervation, a peripheral glial cell web, and a novel S100B expressing interstitial cell type impart structural and functional complexity to the sinoatrial node [PDF]

, 2022
Rostislav Bychkov, Magdalena Juhaszova, Miguel Calvo‐Rubio, Lorenzo A. H. Donald, Claudio Coletta, Chad Shumaker, Kayla Moorman, Syevda Tagirova Sirenko, Alex V. Maltsev, Steven J. Sollott, Edward G. Lakatta   +10 more
openalex   +1 more source