Results 121 to 130 of about 10,498 (222)

Electrical Conduction System Remodeling in Streptozotocin-Induced Diabetes Mellitus Rat Heart

Frontiers in Physiology, 2019
Cardiovascular complications are common in type 1 diabetes mellitus (TIDM) and there is an increased risk of arrhythmias as a result of dysfunction of the cardiac conduction system (CCS). We have previously shown that, in vivo, there is a decrease in the
Yu Zhang, Yu Zhang, Yanwen Wang, Joseph Yanni, Mohammed Anwar Qureshi, Sunil Jit R. J. Logantha, Sarah Kassab, Mark R. Boyett, Natalie J. Gardiner, Hong Sun, Frank Christopher Howarth, Halina Dobrzynski   +11 more
doaj   +1 more source

Postoperative arrhythmia in patients with bidirectional cavopulmonary anastomosis [PDF]

, 2017
OBJECTIVES Bidirectional cavopulmonary anastomosis (BDCPA) is part of the staged Fontan palliation for congenital heart defects with single-ventricle morphology.
Balmer, Christian, Dave, Hitendu, Gass, Matthias, Hug, Maja I., Prêtre, René, Reichlin, Alessandra   +5 more
core  

Selective sinoatrial node optical mapping and the mechanism of sinus rate acceleration [PDF]

, 2012
BACKGROUND: Studies using isolated sinoatrial node (SAN) cells indicate that rhythmic spontaneous sarcoplasmic reticulum calcium release (Ca clock) plays an important role in SAN automaticity.
Chen, Peng-Sheng, Chua, Su-Kiat, Han, Seongwook, Joung, Boyoung, Lin, Shien-Fong, Maruyama, Mitsunori, Park, Hyung-Wook, Shen, Mark J., Shinohara, Tetsuji   +8 more
core   +1 more source

Effects of candesartan, an angiotensin II receptor type I blocker, on atrial remodeling in spontaneously hypertensive rats [PDF]

, 2015
Hypertension-induced structural remodeling of the left atrium (LA) has been suggested to involve the renin–angiotensin system. This study investigated whether treatment with an angiotensin receptor blocker, candesartan, regresses atrial remodeling in ...
Choisy, Stéphanie C., Choisy, Stéphanie C., Hancox, Jules C., James, Andrew F., Jones, Sandra A., Kim, Shang-Jin   +5 more
core   +1 more source

Upregulation of Adenosine A1 Receptors Facilitates Sinoatrial Node Dysfunction in Chronic Canine Heart Failure by Exacerbating Nodal Conduction Abnormalities Revealed by Novel Dual-Sided Intramural Optical Mapping [PDF]

, 2014
Qing Lou, Brian J. Hansen, Olga Fedorenko, Thomas A. Csepe, Anuradha Kalyanasundaram, Ning Li, Lori T. Hage, Alexey V. Glukhov, George E. Billman, Raul Weiss, Peter J. Mohler, Sándor Györke, Brandon J. Biesiadecki, Cynthia A. Carnes, Vadim V. Fedorov   +14 more
openalex   +1 more source

Oral theophylline corrects sinus node dysfunction in acute on chronic lithium toxicity: case report and systematic review of lithium-induced Sinus node dysfunction

Frontiers in Cardiovascular Medicine
IntroductionLithium is a well-known agent to cause systemic toxicity with its narrow therapeutic window. Toxic cardiac effects are known but seldomly reported and can manifest as sinus node dysfunction (SND) ranging from delayed conduction to sinus ...
J. Curran Henson, Lauren Morehead, Joshua Hagood, Niroshi Wijewardane, Hakan Paydak   +4 more
doaj   +1 more source

Subclinical sinus node dysfunction in patients with atrial fibrillation—Insight from ultrahigh‐resolution mapping of human sinoatrial exits [PDF]

, 2022
Tomoya Eguchi, Shinsuke Miyazaki, Toshihiko Tsuji, Moeko Nagao, Shota Kakehashi, Moe Mukai, Takayuki Sekihara, Daisetsu Aoyama, Minoru Nodera, Kanae Hasegawa, Hiroyasu Uzui, Hiroshi Tada   +11 more
openalex   +1 more source

Electrophysiologic effects of lidocaine on sinus node and atrium in patients with and without sinoatrial dysfunction. [PDF]

, 1978
Ramesh C. Dhingra, Prakash Deedwania, Joanne Cummings, F Amat-y-Leon, D Wu, P Denes, Kenneth M. Rosen   +6 more
openalex   +1 more source

SK4 K+ channels are therapeutic targets for the treatment of cardiac arrhythmias

EMBO Molecular Medicine, 2017
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a stress‐provoked ventricular arrhythmia, which also manifests sinoatrial node (SAN) dysfunction.
Shiraz Haron‐Khun, David Weisbrod, Hanna Bueno, Dor Yadin, Joachim Behar, Asher Peretz, Ofer Binah, Edith Hochhauser, Michael Eldar, Yael Yaniv, Michael Arad, Bernard Attali   +11 more
doaj   +1 more source

The electrophysiological effects of Tongyang Huoxue granules on the ignition phase during hypoxia/reoxygenation injury in sinoatrial node cells

Frontiers in Physiology
IntroductionThis study was undertaken to explore the potential therapeutic effects of Tongyang Huoxue Granules (TYHX) on sinoatrial node (SAN) dysfunction, a cardiac disorder characterized by impaired impulse generation or conduction.
Qiaomin Wu, Xing Chang, Yanli Wang, Jinfeng Liu, Xuanke Guan, Zhiming Liu, Ruxiu Liu   +6 more
doaj   +1 more source