Microvascular Rarefaction in the Sinoatrial Node A Potential Mechanism for Pacemaker Dysfunction in Early HFpEF [PDF]
BACKGROUND: Microvascular rarefaction is a feature of heart failure with preserved ejection fraction (HFpEF) that may underlie associated rhythm disturbances.
Muñoz, Manuel F +12 more
core +1 more source
Introduction: Sinus node dysfunction (SND) is a disorder defined by abnormal initiation and conduction of electrical signals from the sinoatrial node. The preferred first-line treatment for a patient with symptomatic SND is a permanent pacemaker implant.
Shivani Lawa +3 more
doaj +1 more source
Adenosine exerts multiple receptor-mediated effects in the heart, including a negative chronotropic effect on the sinoatrial node. The aim of this study was to investigate the distribution of the equilibrative nucleoside transporter rENT1 in rat ...
C.E. Cass +7 more
core +1 more source
Establishment of cardiac action potential recording using a membrane potential indicator in the mouse sinoatrial node [PDF]
The cardiac action potential in the sinoatrial node is important, as it propagates throughout the heart and determines cardiac rhythm. Because of the anatomical complexity, pacemaker cells in the sinoatrial node can be difficult to identify for ...
Higuchi, Shoki +7 more
core +1 more source
Phase response characteristics of sinoatrial node cells
In this work, the dynamic response of the sinoatrial node (SAN), the natural pacemaker of the heart, to short external stimuli is investigated using the Zhang et al. model.
Tsalikakis, D. G. +4 more
core
Identification of CACNA1D variants associated with sinoatrial node dysfunction and deafness in additional Pakistani families reveals a clinical significance. [PDF]
Liaqat K +17 more
europepmc +1 more source
Exercise-Induced Complete Heart Block and Sinoatrial Exit Block in Baseline Bifascicular Block. [PDF]
Gorantla A +5 more
europepmc +1 more source
cAMP-Activated EPAC Signaling Is an Integral Component of Cardiac Pacemaker Cell Automaticity. [PDF]
Vinogradova TM +6 more
europepmc +1 more source
Aging Disrupts L-type Ca<sup>2+</sup> Channel Organization and Function in Pacemaker Cells. [PDF]
Vivas O +9 more
europepmc +1 more source

