Results 101 to 110 of about 10,507 (197)

Catheter Ablation for Frequent Premature Ventricular Contractions or Paroxysmal Supraventricular Tachycardia With Vagal Bradycardia: A New Clinical Application of Superior Vena Cava–Aorta Ganglionated Plexus Modification

open access: yesClinical Cardiology, Volume 49, Issue 4, April 2026.
This study demonstrates that combined RFCA and right atrial Ao‐SVC GP ablation provides a one‐stop, innovative solution for patients with vagal bradycardia and concomitant tachyarrhythmias, significantly improving symptoms and reducing syncope. ABSTRACT Background Frequent premature ventricular contractions (PVCs) or paroxysmal supraventricular ...
Xinai Meng   +6 more
wiley   +1 more source

Clinical characteristics and follow-up of complex arrhythmias associated with RYR2 gene mutations in children

open access: yesFrontiers in Genetics
ObjectiveThe aim of this study was to analyze the diagnosis, treatment, and follow-up of six cases of complex arrhythmias associated with RYR2 gene mutations in children.MethodA retrospective analysis was conducted on six children diagnosed with complex ...
Yefeng Wang   +5 more
doaj   +1 more source

Should socioeconomic factors be considered as traditional risk factors for cardiovascular disease, as confounders, or as risk modifiers? [PDF]

open access: yes, 2008
A large number of studies show that cardiovascular disease and its traditional risk factors are associated with socioeconomic conditions. However, their etiological role in the development of cardiovascular outcomes is not always well understood ...
De Vogli, R., Marmot, M.
core  

Prospects for Creation of Cardioprotective and Antiarrhythmic Drugs Based on Opioid Receptor Agonists [PDF]

open access: yes, 2016
It has now been demonstrated that the μ, δ(1), δ(2), and κ(1) opioid receptor (OR) agonists represent the most promising group of opioids for the creation of drugs enhancing cardiac tolerance to the detrimental effects of ischemia/reperfusion (I/R ...
Bailey A   +64 more
core   +2 more sources

Causal AI in Cardiac Arrhythmia: From Pattern Recognition to Mechanistic Insight

open access: yesClinical Cardiology, Volume 49, Issue 4, April 2026.
Causal artificial intelligence (AI) in Cardiac Arrhythmia: From Pattern Recognition to Mechanistic Insight. Multimodal cardiac data, including electrocardiograms (ECG), wearable device recordings, cardiac imaging, genetic information, and electronic health records, are integrated to support AI‐based analysis. Traditional AI approaches primarily rely on
Bara AbuBaha   +11 more
wiley   +1 more source

Cellular Mechanisms of Sinus Node Dysfunction in Carriers of the SCN5A-E161K Mutation and Role of the H558R Polymorphism

open access: yesFrontiers in Physiology, 2018
Background: Carriers of the E161K mutation in the SCN5A gene, encoding the NaV1.5 pore-forming α-subunit of the ion channel carrying the fast sodium current (INa), show sinus bradycardia and occasional exit block.
Ronald Wilders
doaj   +1 more source

La découverte de l’ivabradine (Procoralan®), inhibiteur sélectif du courant pacemaker If : Une nouvelle approche thérapeutique des cardiopathies ischémiques [PDF]

open access: yes, 2006
L’inhibition du courant pacemakerIf est une cible idéale pour réduire de façon sélective la fréquence cardiaque et constitue une approche thérapeutique attractive pour les cardiopathies ischémiques.
Vilaine, Jean-Paul
core   +1 more source

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu   +11 more
wiley   +1 more source

Oscillatory behavior of P wave duration and PR interval in experimental congestive heart failure: a preliminary study [PDF]

open access: yes, 2018
Objective: The relationship between the autonomic nervous system (ANS) modulation of the sinus node and heart rate variability has been extensively investigated.
Chen, Peng-Sheng   +10 more
core   +2 more sources

Anticholinergic activity and pharmacokinetic parameters of agent SS-68 with properties of class III antiarrhythmic drugs [PDF]

open access: yes, 2016
It was shown that the indole derivate SS-68 (50 and 250 μg/kg intravenous) in acute experiments on cats with neurogenic atrial fibrillation (AF) has a dose-dependent antiarrhythmic action which is associated with the neurotropic influence of this ...
Bogus, S. K.   +4 more
core   +2 more sources

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