Results 81 to 90 of about 5,596 (157)
Loss of Natriuretic Peptide Receptor C Enhances Sinoatrial Node Dysfunction in Aging and Frail Mice. [PDF]
Jansen HJ +4 more
europepmc +1 more source
Microvascular Rarefaction in the Sinoatrial Node: A Potential Mechanism for Pacemaker Dysfunction in Early HFpEF. [PDF]
Microvascular rarefaction is a feature of heart failure with preserved ejection fraction (HFpEF) that may underlie associated rhythm disturbances. Angiotensin II (AngII) signaling has been implicated, but its role in sinoatrial (SA) node dysfunction remains unclear.The authors tested whether changes in SA node microvascular architecture contribute to ...
Manning, Declan +12 more
openaire +1 more source
Shenxian-Shengmai Oral Liquid Improves Sinoatrial Node Dysfunction through the PKC/NOX-2 Signaling Pathway. [PDF]
Zhang H +9 more
europepmc +1 more source
IntroductionThis study was undertaken to explore the potential therapeutic effects of Tongyang Huoxue Granules (TYHX) on sinoatrial node (SAN) dysfunction, a cardiac disorder characterized by impaired impulse generation or conduction.
Qiaomin Wu +6 more
doaj +1 more source
Background: Sinus bradycardia and first-/second-degree atrioventricular (AV) block in athletes are traditionally considered secondary to increased vagal tone and therefore reversible.
Sergei Bondarev +5 more
doaj +1 more source
Millions of people are affected by atrial fibrillation (AF) and heart failure with preserved ejection fraction (HFpEF), two disorders frequently found simultaneously. However, the interrelationship between these intertwined disorders is poorly understood,
Bernadin Ndongson‐Dongmo +2 more
doaj +1 more source
Sinus Bradycardia in Endurance Athletes From Physiological Adaptation to Potential Pathology
Sinus bradycardia is a common electrocardiographic finding in trained athletes and a hallmark feature of the athlete’s heart. Reduced resting heart rate, particularly in endurance athletes, reflects physiological adaptation to long-term intensive ...
Wiktoria Śliwa +9 more
doaj +1 more source
Introduction: Sinus node dysfunction (SND) is a disorder defined by abnormal initiation and conduction of electrical signals from the sinoatrial node. The preferred first-line treatment for a patient with symptomatic SND is a permanent pacemaker implant.
Shivani Lawa +3 more
doaj +1 more source
Metabolic Perturbation Exacerbates Sinoatrial Node Dysfunction in Heart Failure
SUMMARY Heart failure (HF) affects approximately 6.2 million people in the United States, with a 5-year mortality exceeding 50%. Bradyarrhythmia, a known complication in HF due to sinoatrial node (SAN) dysfunction (SAND), increases the morbidity and mortality of HF patients. Insights into the mechanistic underpinnings
Ren, Lu +16 more
openaire +1 more source

