Results 81 to 90 of about 975,812 (179)

Glucagon‐Like Peptide‐1 Agonists and Blood Pressure Regulation: Molecular Mechanisms and Cardiovascular Implications

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Incretin effect helps in regulating glucose homeostasis and maintaining glycaemic control within the human body. This effect is achieved by the two naturally occurring incretin hormones: glucose‐dependent insulinotropic polypeptide (GIP) and glucagon‐like peptide‐1 (GLP‐1).
Nora H. J. Alharbi
wiley   +1 more source

Electrophysiologic effects of lidocaine on sinus node and atrium in patients with and without sinoatrial dysfunction. [PDF]

Circulation, 1978
Electrophysiological studies were conducted in 13 patients with normal sinus node function and 14 with sinus node dysfunction before and after intravenous lidocaine. Mean +/- SEM sinus cycle length significantly shortened from 810 +/- 34.3 to 774 +/- 34.3 msec in patients with normal sinus node (P less than 0.001) and from 1061 +/- 67.6 to 1016 +/- 64 ...
R C, Dhingra, P C, Deedwania, J M, Cummings, F, Amat-Y-Leon, D, Wu, P, Denes, K M, Rosen   +6 more
openaire   +2 more sources

Cardiovascular events follow-up analysis in patients with sinus node dysfunction and implanted pacemaker

Российский кардиологический журнал, 2019
Dysfunction of sinus node (DSN) is the syndrome, characterized by symptoms of tissue hypoperfusion and manifestations on the electrocardiogram and could potentially lead to sudden death. The various impact of different types of pacemakers on life quality
E. A. Badykova, M. R. Badykov, V. V. Plechev, I. Sh. Sagitov, I. A. Lakman, N. Sh. Zagidullin   +5 more
doaj   +1 more source

Exercise and Autonomic Cardiovascular Function—Insights From Spinal Cord‐Injured Humans: A Narrative Review

Acta Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT The cardiovascular response to acute exercise is mediated by the autonomic nervous system (ANS) control mechanisms that modulate vascular resistance to support blood pressure and ensure adequate blood flow to active muscles. These autonomic neurocirculatory control mechanisms include a feedforward mechanism, known as central command, and three
Rasmus Kopp Hansen, Ryan Godsk Larsen, Tom E. Nightingale, Daniel D. Hodgkiss, Niels H. Secher, Stefanos Volianitis   +5 more
wiley   +1 more source

Sinus Node Dysfunction and Atrial Fibrillation Associated with Isolated Sinoatrial Node Artery Ectasia

Electronic Journal of General Medicine, 2013
A 74 year-old female patient was admitted to emergency service with a complaints of dizziness and shortness of breath. Complete atrioventricular block was observed and patient was followed up two days with transient transvenous cardiac pacemaker. Afterthat, atrial fibrillation (AF) was progressed and then, coronary angiography was scheduled.
KARABULUT, Ahmet, UZUNLAR, Bulent
openaire   +2 more sources

Sick Sinus Syndrome and Cerebral Venous Thrombosis: A Connection or Coincidence? A Case Report and Literature Review

Oman Medical Journal
It has been hypothesized that increased intracranial pressure (ICP) may cause sick sinus syndrome (SSS) due to its effect on vagal discharge to the heart, resulting in disruption to the sinus cycle, despite age-related degeneration of the sinoatrial node
Alawi A. Al-Attas, Njood A. Alhrkan, Muteb A. Alwatid, Saifullah M. Zaman, Mohammed F. Salawaty, Nouf A. Mansour   +5 more
doaj   +1 more source

Biointegrated Battery‐Based Electroceuticals

Advanced Materials, Volume 38, Issue 52, 16 September 2026.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou, Zhilian Yue, Zhiqi Chen, Danming Chao, Xiaoteng Jia, Gordon Wallace, Caiyun Wang   +6 more
wiley   +1 more source

Adenylyl cyclase isoform 1 contributes to sinoatrial node automaticity via functional microdomains

JCI Insight, 2022
Sinoatrial node (SAN) cells are the heart’s primary pacemaker. Their activity is tightly regulated by β-adrenergic receptor (β-AR) signaling. Adenylyl cyclase (AC) is a key enzyme in the β-AR pathway that catalyzes the production of cAMP.
Lu Ren, Phung N. Thai, Raghavender Reddy Gopireddy, Valeriy Timofeyev, Hannah A. Ledford, Ryan L. Woltz, Seojin Park, Jose L. Puglisi, Claudia M. Moreno, Luis Fernando Santana, Alana C. Conti, Michael I. Kotlikoff, Yang Kevin Xiang, Vladimir Yarov-Yarovoy, Manuela Zaccolo, Xiao-Dong Zhang, Ebenezer N. Yamoah, Manuel F. Navedo, Nipavan Chiamvimonvat   +18 more
doaj   +1 more source

Cardiac Pacemaker Dysfunction Arising From Different Studies of Ion Channel Remodeling in the Aging Rat Heart

Frontiers in Physiology, 2020
The function of the sinoatrial node (SAN), the pacemaker of the heart, declines with age, resulting in increased incidence of sinoatrial node dysfunction (SND) in older adults.
Aaazh M. Alghamdi, Aaazh M. Alghamdi, Mark R. Boyett, Jules C. Hancox, Jules C. Hancox, Henggui Zhang, Henggui Zhang, Henggui Zhang   +7 more
doaj   +1 more source

Targeted Superior Vena Cava Isolation Combined With Pulmonary Vein Isolation Versus Pulmonary Vein Isolation Alone Using Cryoballoon Ablation for Atrial Fibrillation

Clinical Cardiology, Volume 49, Issue 9, September 2026.
Cryoballoon‐based targeted superior vena cava isolation (SVCI) added to pulmonary vein isolation (PVI) improved 12‐month freedom from atrial tachyarrhythmia compared with PVI alone (90.9% vs. 76.4%, p = 0.037) without increasing complications, supporting systematic SVC trigger assessment in atrial fibrillation ablation. ABSTRACT Background The superior
Yanxin Han, Yangyang Bao, Yun Xie, Yue Wei, Qingzhi Luo, Tianyou Ling, Wenqi Pan, Ning Zhang, Qi Jin, Changjian Lin, Liqun Wu   +10 more
wiley   +1 more source