Results 71 to 80 of about 972,180 (179)

Comparative Efficacy and Safety of Ivabradine vs. Beta Blockers in Heart Transplant Patients: A Systematic Review and Meta‐Analysis

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Elevated resting heart rate in heart transplant (HTx) recipients due to graft denervation is associated with adverse outcomes. Ivabradine and beta blockers are commonly used for heart rate control post‐HTx, but their comparative effectiveness and safety remain unclear.
Ahmad Hassan, Maaz Amir, Mehrab Naeem, Eshah Fatima Ali, Ubaid Ullah, Muhammad Asad Jahangir, Muhammad Umer Hassaan, Rafia Aman, Hafiza Rafia Rifat, Mohammad Faez Nazir, Muhammad Numan Awais, Areeba Alizai, Sidra Gul, Adeena Asif   +13 more
wiley   +1 more source

Electrophysiologic effects of lidocaine on sinus node and atrium in patients with and without sinoatrial dysfunction. [PDF]

Circulation, 1978
Electrophysiological studies were conducted in 13 patients with normal sinus node function and 14 with sinus node dysfunction before and after intravenous lidocaine. Mean +/- SEM sinus cycle length significantly shortened from 810 +/- 34.3 to 774 +/- 34.3 msec in patients with normal sinus node (P less than 0.001) and from 1061 +/- 67.6 to 1016 +/- 64 ...
R C, Dhingra, P C, Deedwania, J M, Cummings, F, Amat-Y-Leon, D, Wu, P, Denes, K M, Rosen   +6 more
openaire   +2 more sources

Cardiovascular events follow-up analysis in patients with sinus node dysfunction and implanted pacemaker

Российский кардиологический журнал, 2019
Dysfunction of sinus node (DSN) is the syndrome, characterized by symptoms of tissue hypoperfusion and manifestations on the electrocardiogram and could potentially lead to sudden death. The various impact of different types of pacemakers on life quality
E. A. Badykova, M. R. Badykov, V. V. Plechev, I. Sh. Sagitov, I. A. Lakman, N. Sh. Zagidullin   +5 more
doaj   +1 more source

Atrial High‐Rate Episodes Mirror Atrial Fibrillation in Stroke Prediction: Evidence From an Indian Prospective Cohort

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
This prospective matched cohort study, which generates hypotheses, finds that device‐detected AF lasting under 24 h is linked to a notably increased risk of stroke/TIA and progression to clinical AF among Indian patients. ABSTRACT Aims To assess the risk of stroke/TIA and progression to atrial fibrillation (AF) in Indian patients with device‐detected ...
Sedhupathi Shanmugam, Sreevilasam P. Abhilash, Jyothi Vijay, Sapna erat Sreedharan, Narayanan Namboodiri   +4 more
wiley   +1 more source

Artificial Intelligence Techniques in Cardiac Neuromodulation: Mechanisms, Applications, and Pathways to Clinical Translation

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
Artificial intelligence could improve patient selection, stimulation control, and response monitoring in cardiac neuromodulation, yet direct clinical evidence remains scarce. We map available techniques onto these three challenges and argue that safe, adaptive closed‐loop control and established therapy efficacy are prerequisites for translation ...
Kshitiz Pandey, Pratik Pandey, Sushmita Khanal, Ashish Panday   +3 more
wiley   +1 more source

Sinus Node Dysfunction and Atrial Fibrillation Associated with Isolated Sinoatrial Node Artery Ectasia

Electronic Journal of General Medicine, 2013
A 74 year-old female patient was admitted to emergency service with a complaints of dizziness and shortness of breath. Complete atrioventricular block was observed and patient was followed up two days with transient transvenous cardiac pacemaker. Afterthat, atrial fibrillation (AF) was progressed and then, coronary angiography was scheduled.
KARABULUT, Ahmet, UZUNLAR, Bulent
openaire   +2 more sources

Sick Sinus Syndrome and Cerebral Venous Thrombosis: A Connection or Coincidence? A Case Report and Literature Review

Oman Medical Journal
It has been hypothesized that increased intracranial pressure (ICP) may cause sick sinus syndrome (SSS) due to its effect on vagal discharge to the heart, resulting in disruption to the sinus cycle, despite age-related degeneration of the sinoatrial node
Alawi A. Al-Attas, Njood A. Alhrkan, Muteb A. Alwatid, Saifullah M. Zaman, Mohammed F. Salawaty, Nouf A. Mansour   +5 more
doaj   +1 more source

The GLP‐1–Mitochondria Axis in Metabolic Aging

Aging Cell, Volume 25, Issue 8, August 2026.
Glucagon‐like peptide‐1 receptor agonists engage AMPK–PGC‐1α signaling to remodel mitochondrial biogenesis, dynamics, and quality control, but downstream effects are context‐dependent and tissue‐specific rather than uniformly receptor‐proximal. Whether this proposed mitochondria‐incretin axis reflects a novel geroscience mechanism or indirect metabolic
Renin Chang, Andy P. Tsai, Boyang Wang, Chia‐Jung Li   +3 more
wiley   +1 more source

Adenylyl cyclase isoform 1 contributes to sinoatrial node automaticity via functional microdomains

JCI Insight, 2022
Sinoatrial node (SAN) cells are the heart’s primary pacemaker. Their activity is tightly regulated by β-adrenergic receptor (β-AR) signaling. Adenylyl cyclase (AC) is a key enzyme in the β-AR pathway that catalyzes the production of cAMP.
Lu Ren, Phung N. Thai, Raghavender Reddy Gopireddy, Valeriy Timofeyev, Hannah A. Ledford, Ryan L. Woltz, Seojin Park, Jose L. Puglisi, Claudia M. Moreno, Luis Fernando Santana, Alana C. Conti, Michael I. Kotlikoff, Yang Kevin Xiang, Vladimir Yarov-Yarovoy, Manuela Zaccolo, Xiao-Dong Zhang, Ebenezer N. Yamoah, Manuel F. Navedo, Nipavan Chiamvimonvat   +18 more
doaj   +1 more source

Cardiac Pacemaker Dysfunction Arising From Different Studies of Ion Channel Remodeling in the Aging Rat Heart

Frontiers in Physiology, 2020
The function of the sinoatrial node (SAN), the pacemaker of the heart, declines with age, resulting in increased incidence of sinoatrial node dysfunction (SND) in older adults.
Aaazh M. Alghamdi, Aaazh M. Alghamdi, Mark R. Boyett, Jules C. Hancox, Jules C. Hancox, Henggui Zhang, Henggui Zhang, Henggui Zhang   +7 more
doaj   +1 more source