Results 61 to 70 of about 972,180 (179)
Familial sinoatrial node dysfunction. Increased vagal tone a possible aetiology. [PDF]
Heart, 1976 Clinical and electrophysiological studies of a 13-year-old boy with sinus bradycardia revealed sinus node dysfunction. Long-term follow-up data of members of his family indicated familial sinus node dysfucntion. Increased vagal tone was present in all patients.
D G, Caralis, P J, Varghese
openaire +2 more sources
Frontiers in Physiology, 2012 Neurotransmitters released from sympathetic and parasympathetic nerve terminals in the SAN exert their effects via G-protein-coupled receptors. Integration of these different G-protein signals within pacemaker cells of the sinoatrial node (SAN) is ...
Alexandra eMighiu, Scott Patrick Heximer
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Atrial fibrillation commonly develops in the left atrium and pulmonary veins (PVs), and can be triggered by sympathetic nerve activity. Here, we examined regional atrial differences in sympathetic nerve distribution and function in the rat.
James Saleeb‐Mousa +6 more
wiley +1 more source
Altered microRNA and mRNA profiles during heart failure in the human sinoatrial node
Scientific Reports, 2021 Heart failure (HF) is frequently accompanied with the sinoatrial node (SAN) dysfunction, which causes tachy-brady arrhythmias and increased mortality. MicroRNA (miR) alterations are associated with HF progression.
Ning Li +13 more
doaj +1 more source
Acta Physiologica, Volume 242, Issue 10, October 2026.ABSTRACT Aim This study aims to investigate whether the Fibroblast Growth Factor 23 (FGF23) modulates the electrical activity of sinoatrial (SAN) cells. The canonical function of FGF23 is to regulate body phosphorus and calcium homeostasis by activating the FGF1 receptors (FGFR1)/α‐Klotho complex in the kidney and parathyroid glands.
Giorgia Bertoli +10 more
wiley +1 more source
PLOS Digital Health, 2022 Understanding the conditionally-dependent clinical variables that drive cardiovascular health outcomes is a major challenge for precision medicine.
Sergiusz Wesołowski +14 more
doaj +1 more source
Neurocardiology: Brain–Heart Interactions in the Heart
MedComm, Volume 7, Issue 9, September 2026.The heart and brain maintain systemic homeostasis through bidirectional communication involving neural, biochemical, and mechanical pathways. Dysregulation of these pathways contributes to a spectrum of conditions involving heart–brain interactions, including Takotsubo syndrome, the epileptic heart, stroke–heart syndrome, heart failure, cardiac ...
Wentao Wang +3 more
wiley +1 more source
Temporary neonatal atrial pacing through the umbilical venous route: A novel technique
Annals of Pediatric Cardiology, 2011 Atrial pacing in the neonate is rarely done due to constraints of equipment, technical knowhow, and risk of complications. We describe a novel method of atrial pacing in the new born using equipment readily available in any intensive care unit.
Hiren N Doshi, Seema T Lokare
doaj +1 more source
Clinical Cardiology, Volume 49, Issue 8, August 2026.Patients with hypertrophic cardiomyopathy had significantly higher risks of bradyarrhythmia and permanent pacemaker implantation than matched controls. Among patients with HCM, atrial fibrillation increased the risks of both outcomes, while heart failure was associated with a higher risk of permanent pacemaker implantation.
Tsu‐An Yang +15 more
wiley +1 more source
A Closed‐Loop Cardiovascular Model of the Supine‐To‐Stand Manoeuvre: Implications for Falls
International Journal for Numerical Methods in Biomedical Engineering, Volume 42, Issue 8, August 2026.Continuous beat‐to‐beat modeling of supine‐to‐stand hemodynamics in older adults reproduces orthostatic responses and reveals differences in baroreflex, muscle‐pressure, and blood volume in those with a fall history, providing a basis for mechanistic phenotyping to enhance orthostatic hypotension diagnosis.
Joeri A. van de Sande +7 more
wiley +1 more source