Results 31 to 40 of about 39,633 (292)

Sirius

open access: yes, 2023
This is the official repository of the paper "Sirius: A Self-Localization System for Resource-Constrained IoT Sensors" presented in Mobisys 2023. Please refer to our research group website for more details: http://icosmos.cs.umd.edu/ https://www.cs ...
Nakul Garg, Nirupam Roy
core   +1 more source

Phosphorylated STYK1 Promotes Gemcitabine Resistance via Autophagy‐Mediated Cancer Stemness in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Gemcitabine resistance remains a major challenge in pancreatic ductal adenocarcinoma. This study identifies STYK1 as a key mediator of chemoresistance through autophagy‐dependent maintenance of cancer stemness. Gemcitabine‐activated AMPK phosphorylates STYK1 at Ser91 and Ser304, enhancing autophagy and stemness.
Xueying Dong   +20 more
wiley   +1 more source

Lipocalin‐2 activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed Ob/Ob mice

open access: yesHepatology, EarlyView., 2022
Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim   +12 more
wiley   +1 more source

DNA Barcoding for Managing Blackberry Genetic Resources on Black Sea Coast (Russia)

open access: yesDiversity
Accurate species identification in blackberries (Rubus spp.) is difficult because of morphological similarity and frequent hybridization. We studied 56 wild accessions from the Sirius Federal Territory (Russia), representing coastal and foothill ...
Igor Yu. Zhuravlev   +11 more
doaj   +1 more source

Reproducing analysis of Sirius model simulations of wheat yields, 1892-2016

open access: yes, 2021
R Markdown file showing analysis steps for graphics showing simulated wheat yields and harvest index from 1892-2016 from the Sirius model using observed meteorological data for Rothamsted, Hertfordshire, UK, combined with both observed CO2 levels from ...
Semenov, M. A., Mead, A., Addy, J.
core  

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang   +11 more
wiley   +1 more source

ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver

open access: yesHepatology, EarlyView., 2022
Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid   +20 more
wiley   +1 more source

Development of a Multiplexed Fluorescent Pseudovirus Neutralization Test for Simultaneous Assessment of Immunity to Three SARS-CoV-2 Variants

open access: yesImmuno
In the post-pandemic era, monitoring adaptive immunity of the population to emerging SARS-CoV-2 variants remains an important public health priority. To address this need, we developed a test that can simultaneously assess the neutralization ability of ...
Sofia M. Gulova   +6 more
doaj   +1 more source

Caltoris sirius subsp. sirius Swift

open access: yes, 2021
9. Caltoris sirius sirius (Evans, 1926) (Sirius Swift) Remarks. On 12.xii.2016, two individuals were recorded, nectaring on Marigold flower at Kameswar Village (24°22’21” N & 92°10’47” E, ca. 15 m above msl.). This species is rare throughout the state. Current known distribution.
openaire   +2 more sources

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

open access: yesAdvanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai   +18 more
wiley   +1 more source

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