Results 81 to 90 of about 82,161 (336)
BMC Cardiovascular Disorders, 2005 Background Sirolimus-eluting stents (CYPHER stents) demonstrated remarkable efficacy in reducing restenosis rates in patients with coronary artery disease. There is a concern of sub-acute and late stent thrombosis.
Ming Xiu-Fen +4 more
doaj +1 more source
International Journal of Cancer, 2020 Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor in children, which can be accompanied by life‐threatening thrombocytopenia, referred to as Kasabach‐Merritt phenomenon (KMP).
R. Brill +25 more
semanticscholar +1 more source
Mechanism-based strategies for the management of autoimmunity and immune dysregulation in primary immunodeficiencies [PDF]
, 2016 A broad spectrum of autoimmunity is now well described in patients with primary immunodeficiencies (PIDs). Management of autoimmune disease in the background of PID is particularly challenging given the seemingly discordant goals of immune support and ...
Cooper, Megan A +4 more
core +2 more sources
The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
Advanced Science, EarlyView.This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen +6 more
wiley +1 more source
Drug Interaction between Sirolimus and Ranolazine in a Kidney Transplant Patient
Case Reports in Transplantation, 2014 Purpose. The case of a kidney transplant recipient who experienced a probable drug interaction between sirolimus and ranolazine is reported. Summary.
Joanna C. Masters +2 more
doaj +1 more source
Treatment of Lymphatic Malformations with the mTOR Inhibitor Sirolimus: A Systematic Review.
Lymphatic Research and Biology, 2018 BACKGROUND Extensive lymphatic malformations are low-flow vascular malformations that can cause devastating complications. Treatment of these malformations is challenging.
S. Wiegand, G. Wichmann, A. Dietz
semanticscholar +1 more source
Patients with Congenital Low-Flow Vascular Malformation Treated with Low Dose Sirolimus
Advances in Therapy, 2020 Patients with congenital vascular malformations often suffer from an impaired quality of life (QoL) because of pain and functional disabilities. Previous studies have shown that the mTOR inhibitor sirolimus can reduce complaints and improve QoL in some ...
Veroniek E. M. Harbers +8 more
semanticscholar +1 more source
Dramatic Response to Sirolimus in Lymphangioleiomyomatosis [PDF]
Canadian Respiratory Journal, 2013 Depatrment of Respirology, University of Toronto, Toronto General Hospital, Toronto, Ontario Correspondence: Dr Dmitry Rozenberg, Depatrment of Respirology, Toronto General Hospital, 9N 965 – 585 University Avenue, Toronto, Ontario M5G 2N2. Telephone 416-340-4591, fax 416-340-3109, e-mail dmitry.rozenberg@uhn.ca A 41-year-old woman presented with a one-
Rozenberg, Dmitry, Thenganatt, John
openaire +5 more sources
Expert Perspective: Diagnosis and Treatment of Castleman Disease
Arthritis &Rheumatology, Accepted Article.Summary Castleman disease (CD) is a major diagnostic challenge for Rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y.C. Chen +2 more
wiley +1 more source
Frontiers in Immunology, 2022 BackgroundThrombocytopenia (TP) is considered as a warning sign of high-risk antiphospholipid syndrome (APS) and sometimes a paradoxical sign of anti-thrombosis treatment.
Wenhui Xie, Lanlan Ji, Zhuoli Zhang
doaj +1 more source