Results 81 to 90 of about 117,553 (304)

Automated processing of whole blood samples for the determination of immunosuppressants by liquid chromatography tandem-mass spectrometry [PDF]

, 2006
Background: Liquid chromatography tandem-mass spectrometry (LC-MS/MS) is an efficient technology for routine determination of immunosuppressants in whole blood; however, time-consuming manual sample preparation remains a significant limitation of this ...
Spöhrer, Ute, Vogeser, Michael
core   +1 more source

Targeted therapy with a localised abluminal groove, low-dose sirolimus-eluting, biodegradable-polymer coronary stent – five-year results of the TARGET All Comers randomised clinical trial [PDF]

, 2023
Alexandra J. Lansky, Bo Xu, Andreas Baumbach, Henning Kelbæk, Niels van Royen, Ming Zheng, Paul Knaapen, Ton Slagboom, Tom Johnson, Georgios J. Vlachojannis, Karin Arkenbout, Lene Holmvang, Luc Janssens, Salvatore Brugaletta, Christoph Naber, Thomas Schmitz, Richard Anderson, Harald Rittger, Sérgio Berti, Emanuele Barbato, Gábor G. Tóth, Luc Maillard, Christian Valina, Paweł Buszman, Hölger Thiele, Volker Schächinger, William Wijns   +26 more
openalex   +1 more source

The impact of sirolimus therapy on lesion size, clinical symptoms, and quality of life of patients with lymphatic anomalies

Orphanet Journal of Rare Diseases, 2019
BackgroundLymphatic anomalies (LAs) include several disorders in which abnormal lymphatic tissue invades the neck, chest, and various organs. Progressive cases may result in lethal outcomes and have proven difficult to treat.
M. Ozeki, Akifumi Nozawa, Shiho Yasue, S. Endo, Ryuta Asada, H. Hashimoto, T. Fukao   +6 more
semanticscholar   +1 more source

Beyond a Conduit: The Evolution of Functional Biliary Stents From Active Intervention to Enabling Platforms

iNew Medicine, EarlyView.
This review traces the evolution of functional biliary stents, outlining the paradigm shift from “active intervention” strategies that target stent failure to next‐generation “enabling platforms.” These platforms leverage biodegradable materials, 3D/4D printing, and smart sensors to achieve personalized, regenerative, and theranostic solutions ...
Muhan Li, Xu Liu, Xin Ye, Zhixia Dong, Xinjian Wan   +4 more
wiley   +1 more source

Drug Interaction between Sirolimus and Ranolazine in a Kidney Transplant Patient

Case Reports in Transplantation, 2014
Purpose. The case of a kidney transplant recipient who experienced a probable drug interaction between sirolimus and ranolazine is reported. Summary.
Joanna C. Masters, Mita M. Shah, Ashley A. Feist   +2 more
doaj   +1 more source

Development and Physicochemical Characterization of Sirolimus Solid Dispersions Prepared by Solvent Evaporation Method [PDF]

Advanced Pharmaceutical Bulletin, 2014
Purpose: The aim of the present investigation was preparation and characterization of sirolimus solid dispersions by solvent evaporation technique to improve its dissolution properties.
Shahram Emami, Hadi Valizadeh, Ziba Islambulchilar, Parvin Zakeri-Milani   +3 more
doaj   +1 more source

Sirolimus is efficacious in treatment for extensive and/or complex slow-flow vascular malformations: a monocentric prospective phase II study

Orphanet Journal of Rare Diseases, 2018
BackgroundExtensive and complex vascular malformations often cause chronic pain and severe functional restraint. Conventional treatments, such as surgery and/or sclerotherapy, are rarely curative, underscoring the great need for new therapeutic ...
J. Hammer, Emmanuel Seront, Steven Duez, S. Dupont, An Van Damme, S. Schmitz, C. Hoyoux, C. Chopinet, P. Clapuyt, F. Hammer, M. Vikkula, L. Boon   +11 more
semanticscholar   +1 more source

Clinical presentation, treatment, and outcome of children with primary intestinal lymphangiectasia: A national retrospective study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Primary intestinal lymphangiectasia (PIL) is a very rare disease responsible for protein‐losing enteropathy. There is little published data about treatments efficacy and outcomes. Our main objective was to describe the clinical profile, response to therapy, and outcomes of children with PIL.
Noémie Goret, Cécile Lambe, Emmanuelle Ecochard‐Dugelay, Alexandre Fabre, Alain Dabadie, Aurélie Comte, Julie Rebeuh, Pierre Poinsot, Emilie Chaillou, Haude Clouzeau, Aurélie Sabard, Béatrice Dubern, Stéphanie Willot   +12 more
wiley   +1 more source

Functional improvements in patients with lymphangioleiomyomatosis after sirolimus: an observational study

Orphanet Journal of Rare Diseases, 2018
Background Sirolimus has been shown to be effective in patients with lymphangioleiomyomatosis (LAM). We wish to summarize our experience using sirolimus and its effectiveness in LAM patients.
Yongzhong Zhan, Lisha Shen, Wenshuai Xu, Xiuxiu Wu, Weihong Zhang, Jun Wang, Xue Li, Yanli Yang, Xinlun Tian, Kai-Feng Xu   +9 more
doaj   +1 more source

Macromolecular approaches to prevent thrombosis and intimal hyperplasia following percutaneous coronary intervention. [PDF]

, 2014
Cardiovascular disease remains one of the largest contributors to death worldwide. Improvements in cardiovascular technology leading to the current generation of drug-eluting stents, bioresorbable stents, and drug-eluting balloons, coupled with advances ...
Panitch, Alyssa, Scott, Rebecca A
core   +2 more sources