Results 81 to 90 of about 60,209 (283)

The Relationship Between Serum SFRP5, ApoA‐I, HDL3‐C Level and In‐Stent Restenosis After PCI in Acute Myocardial Infarction and the Combined Predictive Value

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aims to investigate the relationship between serum secreted frizzled‐related protein 5 (SFRP5), apolipoprotein A‐I (ApoA‐I), high‐density lipoprotein 3‐cholesterol (HDL3‐C) and in‐stent restenosis (ISR) after percutaneous coronary intervention (PCI) in acute myocardial infarction (AMI) and their combined predictive value.
Li‐Qiang Cui, Xue‐Dong Wang
wiley   +1 more source

Verrucous venous malformation [PDF]

open access: yes, 2019
Verrucous venous malformation, also known as verrucous hemangioma, is a superficial vascular malformation with a variable degree of hyperkeratosis that is composed of capillaries and veins in the dermis and sometimes subcutaneous tissue. We describe a 53-
Kim, Gene H   +2 more
core  

Sirolimus in the Treatment of Vascular Anomalies [PDF]

open access: yesEuropean Journal of Pediatric Surgery, 2016
Aim of the Study mTOR inhibitors are showing promising results in the management of vascular anomalies. Although current controlled trials remain to be completed, many individual experiences are being published. We present our series of children with complex vascular anomalies treated with sirolimus.
Juan Carlos López-Gutiérrez   +7 more
openaire   +2 more sources

Solubilization of Sirolimus in Aqueous Solution Through Complexation with Metal Ions [PDF]

open access: yes, 2013
Sirolimus is one of the most successful immunosuppressant drugs available but it has an extremely low solubility in water that dramatically limits its oral bioavailability to approximately 20%.
Falen, Ralph A.
core   +1 more source

Posttransplant EBV‐positive Smooth Muscle Tumors in Children, Adolescents, and Young Adults: A Multi‐Institution Experience

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Epstein–Barr virus (EBV)‐positive smooth muscle tumors (SMTs) are rare tumors seen in immunocompromised patients. There is no clear standard of care for the management and treatment of EBV‐SMTs. Patients are often treated with chemotherapy, surgery, and/or radiation.
Meghan Haney   +7 more
wiley   +1 more source

Low-Dose Sirolimus Immunoregulation Therapy in Patients with Active Rheumatoid Arthritis: A 24-Week Follow-Up of the Randomized, Open-Label, Parallel-Controlled Trial

open access: yesJournal of Immunology Research, 2019
Background. We have reported previously the insufficient absolute number or functional defects of regulatory T cells (Tregs) in patients with rheumatoid arthritis (RA), challenging conventional unspecific immunosuppressive therapy.
Hong-Yan Wen   +19 more
doaj   +1 more source

Malignant and noninvasive skin tumours in renal transplant recipients. [PDF]

open access: yes, 2014
Background. Transplant recipients require immunosuppression to prevent graft rejection. This conveys an increased risk of malignancy, particularly skin tumours. There is a need for up-to-date data for the South of England. Method.
Chow, JW   +5 more
core   +2 more sources

Nanomedicine Approaches for Autophagy Modulation in Cancer Therapy

open access: yesSmall Science, EarlyView.
Autophagy modulation holds promise for enhancing cancer treatment, yet clinical translation remains challenging. This review explores nanomedicine‐based strategies to improve autophagy‐targeting drugs, highlighting their synergy with chemotherapy, immunotherapy, phototherapy, and gene therapy. It also discusses nanoparticle design and clinical progress,
Sohaib Mahri   +11 more
wiley   +1 more source

Enhanced bioavailability of sirolimus via preparation of solid dispersion nanoparticles using a supercritical antisolvent process

open access: yesInternational Journal of Nanomedicine, 2011
Min-Soo Kim1, Jeong-Soo Kim1, Hee Jun Park1, Won Kyung Cho1,3, Kwang-Ho Cha1,3, Sung-Joo Hwang2,31College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea, 2College of Pharmacy, 3Yonsei Institute of Pharmaceutical Sciences, Yonsei ...
Kim MS   +5 more
doaj  

Segmental Congenital Vascular Anomaly With Atrophy, Ulceration and Scarring With Complications in Pregnancy

open access: yesAustralasian Journal of Dermatology, EarlyView.
ABSTRACT A 33‐year‐old woman with a segmental non‐involuting congenital vascular anomaly of the left neck developed pain and ulceration in pregnancy and left‐sided Horner's syndrome after delivery. Mutational analysis of affected tissue showed a missense mutation in GNA11 (Glu209) and a second mutation in PIK3CA.
Anne R. Halbert   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy