Results 81 to 90 of about 70,065 (194)

Somatic Mutations in Acquired Pure Red Cell Aplasia: Incidence and Implications

open access: yes
American Journal of Hematology, Volume 101, Issue 7, Page 1554-1555, July 2026.
Robert T. Means Jr
wiley   +1 more source

Budget impact analysis of conversion from cyclosporine to sirolimus as immunosuppressive medication in renal transplantation therapy

open access: yes, 2013
Naghmeh Foroutan,1 Hamid R Rasekh,1 Jamshid Salamzadeh,1 Hamid R Jamshidi,1 Mohsen Nafar2 1Department of Pharmacoeconomics and Pharmaceutical Management, School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2Department of Kidney ...
Foroutan N   +4 more
core  

Use of Sirolimus in Kidney Transplantation

open access: yes, 2001
Sirolimus, which has a distinctive mechanism of action that inhibits cytokine-driven cell proliferation and maturation, provides an exciting addition to the immunosuppressive regimen for organ transplantation.
Jeanette Podbielski, Linda Schoenberg
core   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

open access: yesiNew Medicine, Volume 2, Issue 2, June 2026.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu   +5 more
wiley   +1 more source

Sirolimus-induced lymphoedema

open access: yes, 2016
Sirolimus is an inhibitor of the mammalian target of rapamycin (mTOR), used as an immunosuppressant for solid-organ transplant recipients and patients with autoimmune disorders.
Mashabane, M.J., Motse, K.G.
core  

In vitro pharmacokinetics of sirolimus-coated stent for tracheal stenosis

open access: yes, 2017
Purpose: To investigate the in vitro pharmacokinetics of sirolimus-coated stent for tracheal stenosisMethods: Naked nickel titanium alloy stent was placed in methylene chloride leaching solution with different ratios of sirolimus/poly(lactic-co-glycolic ...
Wang, Shanzuan   +5 more
core   +1 more source

Ageing‐Associated Dysregulation of Myogenic Differentiation in Inclusion Body Myositis

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Skeletal muscle is a postmitotic tissue dependent on a complex and tightly regulated regeneration process involving numerous intracellular and extracellular factors, including myogenic regulatory factors (MRFs), cytokines and myokines. Quiescent satellite cells are activated by physiological stimuli, injury or other traumatic insults for the ...
Geert M. de Vries   +2 more
wiley   +1 more source

SİROLİMUS VE TAKROLİMUS’UN KARACİĞER YENİLENMESİNE ETKİSİ

open access: yes, 2014
Amaç: Bu çalışmada parsiyel hepatektomi yapılan farelerde sirolimus ve takrolimusun, kortikosteroid uygulandığında ve uygulanmadığı durumda, karaciğer yenilenmesine olan etkileri araştırıldı.
Şafak Öztürk   +7 more
core  

Individualized immunosuppression in transplant patients: potential role of pharmacogenetics.

open access: yes, 2012
The immunosuppressive drugs used to prevent the rejection of transplanted organs have a narrow therapeutic index. Under treatment results in episodes of rejection leading to either damage or loss of the organ. Over immunosuppression increases the risk of
MacPhee IA   +3 more
core   +1 more source

RASGRP1 Deficiency Manifesting as Severe Vasculopathy and Fatal Autoimmune Hemolytic Anemia

open access: yeseJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Background RASGRP1 deficiency is a rare inborn error of immunity characterized by immunodeficiency, autoimmunity, and lymphoproliferation. Results We report a 5‐year‐old male with novel homozygous splice‐donor mutations in RASGRP1(c.1720+1G>A and c.1720+2T>C) who presented with severe vasculopathy (ischemic stroke and thrombosis), secondary ...
Kosar Asna Ashari   +5 more
wiley   +1 more source

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