Results 81 to 90 of about 70,065 (194)
Somatic Mutations in Acquired Pure Red Cell Aplasia: Incidence and Implications
American Journal of Hematology, Volume 101, Issue 7, Page 1554-1555, July 2026.
Robert T. Means Jr
wiley +1 more source
Naghmeh Foroutan,1 Hamid R Rasekh,1 Jamshid Salamzadeh,1 Hamid R Jamshidi,1 Mohsen Nafar2 1Department of Pharmacoeconomics and Pharmaceutical Management, School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2Department of Kidney ...
Foroutan N +4 more
core
Use of Sirolimus in Kidney Transplantation
Sirolimus, which has a distinctive mechanism of action that inhibits cytokine-driven cell proliferation and maturation, provides an exciting addition to the immunosuppressive regimen for organ transplantation.
Jeanette Podbielski, Linda Schoenberg
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Vascular Calcification: Mechanisms, Models, and Therapies
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu +5 more
wiley +1 more source
Sirolimus is an inhibitor of the mammalian target of rapamycin (mTOR), used as an immunosuppressant for solid-organ transplant recipients and patients with autoimmune disorders.
Mashabane, M.J., Motse, K.G.
core
In vitro pharmacokinetics of sirolimus-coated stent for tracheal stenosis
Purpose: To investigate the in vitro pharmacokinetics of sirolimus-coated stent for tracheal stenosisMethods: Naked nickel titanium alloy stent was placed in methylene chloride leaching solution with different ratios of sirolimus/poly(lactic-co-glycolic ...
Wang, Shanzuan +5 more
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Ageing‐Associated Dysregulation of Myogenic Differentiation in Inclusion Body Myositis
ABSTRACT Skeletal muscle is a postmitotic tissue dependent on a complex and tightly regulated regeneration process involving numerous intracellular and extracellular factors, including myogenic regulatory factors (MRFs), cytokines and myokines. Quiescent satellite cells are activated by physiological stimuli, injury or other traumatic insults for the ...
Geert M. de Vries +2 more
wiley +1 more source
SİROLİMUS VE TAKROLİMUS’UN KARACİĞER YENİLENMESİNE ETKİSİ
Amaç: Bu çalışmada parsiyel hepatektomi yapılan farelerde sirolimus ve takrolimusun, kortikosteroid uygulandığında ve uygulanmadığı durumda, karaciğer yenilenmesine olan etkileri araştırıldı.
Şafak Öztürk +7 more
core
Individualized immunosuppression in transplant patients: potential role of pharmacogenetics.
The immunosuppressive drugs used to prevent the rejection of transplanted organs have a narrow therapeutic index. Under treatment results in episodes of rejection leading to either damage or loss of the organ. Over immunosuppression increases the risk of
MacPhee IA +3 more
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RASGRP1 Deficiency Manifesting as Severe Vasculopathy and Fatal Autoimmune Hemolytic Anemia
ABSTRACT Background RASGRP1 deficiency is a rare inborn error of immunity characterized by immunodeficiency, autoimmunity, and lymphoproliferation. Results We report a 5‐year‐old male with novel homozygous splice‐donor mutations in RASGRP1(c.1720+1G>A and c.1720+2T>C) who presented with severe vasculopathy (ischemic stroke and thrombosis), secondary ...
Kosar Asna Ashari +5 more
wiley +1 more source

