Results 101 to 110 of about 35,822 (223)

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, Volume 183, Issue 7, Page 1313-1340, April 2026.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

Evaluating the Geo-Environmental Conditions within a Working Face Using a Hybrid Intelligent Optimization Model

Applied Sciences
Geological anomalies within the working face likely induce geological disasters, such as water, gas, and coal mine roof fall, directly impacting the rational planning and safe mining of underground resources.
Changfang Guo, Tingjiang Tan, Liuzhu Ma, Zhicong Zhang, Xiaoping Ma, Difei Zhao, Wenhua Jiao   +6 more
doaj   +1 more source

Security Incident Response Criteria: A Practitioner's Perspective [PDF]

, 2015
Industrial reports indicate that security incidents continue to inflict large financial losses on organizations. Researchers and industrial analysts contend that there are fundamental problems with existing security incident response process solutions.
Glisson, William Bradley, Grispos, George, Storer, Timothy   +2 more
core   +1 more source

Thermomechanics of Picoliter Liquids Encapsulated in Metal Microarchitectures

Advanced Materials, Volume 38, Issue 17, 20 March 2026.
Picoliter‐scale water is encapsulated inside hollow copper microcylinders through a single‐step localized electrodeposition process. Mechanical testing at room and cryogenic temperatures reveals that incompressible liquid and load‐bearing microscale ice enhance the strength and deformation behavior of the composite structure.
Sung‐Gyu Kang, Kyeongjae Jeong, Bárbara Bellón, Lalith Kumar Bhaskar, Leonardo Shoji Aota, Jeongin Paeng, Dipali Sonawane, Kuan Ding, Se‐Ho Kim, Allison Goetz, Benjamin Apeleo Zubiri, Erdmann Spiecker, Ayman El‐Zoka, Baptiste Gault, Gerhard Dehm, Rajaprakash Ramachandramoorthy   +15 more
wiley   +1 more source

Liver Metastases in Pancreatic Acinar Cell Carcinoma Treated with Selective Internal Radiation Therapy with Y-90 Resin Microspheres

Case Reports in Hepatology, 2017
Background. Pancreatic acinar cell carcinoma (PACC) is a rare tumor. Surgical resection is the treatment of choice when feasible, but there are no clear recommendations for patients with advanced disease.
Felipe Nasser, Joaquim Maurício Motta Leal Filho, Breno Boueri Affonso, Francisco Leonardo Galastri, Rafael Noronha Cavalcante, Diego Lima Nava Martins, Vanderlei Segatelli, Lilian Yuri Itaya Yamaga, Rene Claudio Gansl, Bernardino Tranchesi Junior, Antônio Luiz de Vasconcellos Macedo   +10 more
doaj   +1 more source

Rethinking Security Incident Response: The Integration of Agile Principles [PDF]

, 2014
In today's globally networked environment, information security incidents can inflict staggering financial losses on organizations. Industry reports indicate that fundamental problems exist with the application of current linear plan-driven security ...
Glisson, William Bradley, Grispos, George, Storer, Tim   +2 more
core   +2 more sources

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

Advanced Science, Volume 13, Issue 14, 9 March 2026.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai, Yaqi Li, Shengnan Liu, Minjuan Wu, Zhixiao Liu, Junfeng Jiang, Jingjing Chen, Xiaoding Xu, Li Li, Chaoqun Li, Fang Zhao, Ye Liu, Haitao Ni, Tengfei Zhang, Mingjuan Xu, Chaofeng Han   +15 more
wiley   +1 more source

Echoes of Populism and Terrorism in Libya’s Online News Reporting [PDF]

, 2018
This article focuses on news reporting in Libya, assessing both official and citizen journalism. Special attention is paid to online resources, primarily spontaneous posts written in Arabic. Social media shows the emergence of citizen journalism together
Lombezzi, Letizia
core  

Mitophagy and Ubiquitination Coordinate Context‐Specific Mitochondrial Quality Control and EMT/MET Plasticity to Drive Cancer Cell Invasion

Advanced Science, Volume 13, Issue 16, 18 March 2026.
Metastatic invasion emerges when tumor‐intrinsic programs and microenvironmental forces converge on mitochondrial quality control. A context‐stratified framework links mtROS, mtDNA integrity, mechanics and nutrient/oxygen cues to fission–fusion remodeling, mtUPR and mitophagy.
Bin‐Hsu Mao, Bo‐Kai Su, Ying‐Jan Wang, Ting‐Yuan Tu   +3 more
wiley   +1 more source

Application of a simultaneous iterations reconstruction technique for a 3-D water vapor tomography system

Geodesy and Geodynamics, 2013
The simultaneous iterations reconstruction technique (SIRT) is one of several reconstruction algorithms of the ART family. It is used widely in tomography because of its convenience in dealing with large sparse matrices.
Wang Wei, Ye Biwen, Wang Jiexian
doaj   +1 more source