Results 191 to 200 of about 65,710 (330)

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

TARGETING SIRTUIN 1 IN TYPE 2 DIABETES MELLITUS: A NOVEL APPROACH

ERA KARN, SUMAN BALA SHARMA, PREETI YADAV, THURAYA ABDULSALAM A.A. ALAZAZI, MONTEY NARUKA, NIRUPMA GUPTA, MANOJ KUMAR NANDKEOLIAR   +6 more
openalex   +1 more source

Saccharomyces boulardii modulates necrotizing enterocolitis in neonatal mice by regulating the sirtuin 1/NF‑κB pathway and the intestinal microbiota

, 2020
Kun Zhang, Xi Zhang, Anping Lv, Sainan Fan, Jinping Zhang   +4 more
openalex   +2 more sources

Enviromimetics: From exercise mimetics to cognitomimetics in the quest for enhanced brain health and cognition

The Journal of Physiology, EarlyView.
Abstract figure legend A schematic diagram outlining the concept of enviromimetics, and the subclasses of exercise mimetics, epimimetics and cognitomimetics. The rationale is that environmental stimulation and lifestyle factors, including physical activity and cognitive stimulation, have shown beneficial effects across a range of human conditions ...
Anthony J. Hannan
wiley   +1 more source

Sirtuin 1 and Sirtuin 2 Gene Expressions in Colorectal Cancers. [PDF]

J Clin Pract Res
Düzenli T, Doğan D, Barışık NÖ.
europepmc   +1 more source

RETRACTED: Sirtuin 2 Isoform 1 Enhances Hepatitis B Virus RNA Transcription and DNA Synthesis through the AKT/GSK-3β/β-Catenin Signaling Pathway [PDF]

, 2018
Zahra Zahid Piracha, Hyeonjoong Kwon, Umar Saeed, Jumi Kim, Jaesung Jung, Yong‐Joon Chwae, Sun Park, Ho‐Joon Shin, Kyongmin Kim   +8 more
openalex   +1 more source

Early sensorimotor restriction in rats induces age‐dependent mitochondrial alterations in skeletal muscles and brain structures

The Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to determine whether early sensorimotor restriction (SMR) alters mitochondrial enzyme activities in rat muscles and brain structures. SMR was induced via immobilizing the hind limbs of pups for 16 h per day during the dark phase from birth to postnatal day (PND) 28.
Mélanie Van Gaever, Olivier Dupuy, Erwan Dupont, Marie‐Hélène Canu, Frederic Daussin   +4 more
wiley   +1 more source

The NAD-Dependent Deacetylase Sirtuin-1 Regulates the Expression of Osteogenic Transcriptional Activator Runt-Related Transcription Factor 2 (Runx2) and Production of Matrix Metalloproteinase (MMP)-13 in Chondrocytes in Osteoarthritis [PDF]

, 2016
Koh Terauchi, Hajime Kobayashi, Kanaka Yatabe, Naoko Yui, Hiroto Fujiya, Hisateru Niki, Haruki Musha, Kazuo Yudoh   +7 more
openalex   +1 more source

Pregnancy shifts endothelial progenitor cell morphology and function: Role of metabolism, pro‐inflammatory cytokines and fetal sex

The Journal of Physiology, EarlyView.
Abstract figure legend We recruited non‐pregnant women (NP), women in early pregnancy (EP) and late pregnancy (LP) for isolation of endothelial colony forming cells (ECFCs) via density gradient centrifugation. Plasma supernatant was collected for analysis of markers of glucose and lipid metabolism (fasting glucose, triglycerides, cholesterol, low ...
Marie‐Therese Weiser‐Fuchs, Andreas Jantscher, Simone Tischler, Elena Osto, Lusik Balayan, Hubert Scharnagl, Gabriele Jäger, Bettina Amtmann, Azra Kulovic‐Sissawo, Sabrina Puster, Herbert Fluhr, Barbara Obermayer‐Pietsch, Christina Stern, Ursula Hiden, Evelyn Jantscher‐Krenn   +14 more
wiley   +1 more source

The Relationship Between Aortic Tissue Sirtuin 1 Levels and Type A Aortic Dissections and Ascending Aortic Aneurysms. [PDF]

Braz J Cardiovasc Surg
Rum M, Ketenci B, Kizilyel F, Johnson BS, Celik U, Yildiz BEG, Ozhan A.   +6 more
europepmc   +1 more source