Results 321 to 330 of about 65,710 (330)

The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

Cell, 2013
Laurent Mouchiroud, Riekelt H Houtkooper, Elena Katsyuba   +2 more
exaly  

Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals)

Journal of Medicinal Chemistry, 2018
Matthias Schiedel, Attila Lehotzky, Dina Robaa   +2 more
exaly  

The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

Nature Reviews Molecular Cell Biology, 2008
Xiang-Jiao Yang, Edward Seto
exaly  

Host sirtuin 1 regulates mycobacterial immunopathogenesis and represents a therapeutic target against tuberculosis

Science Immunology, 2017
Catherine Y Cheng, Nuria Martinez Gutierrez, Mardiana B Marzuki   +2 more
exaly  

The sirtuin pathway in ageing and Alzheimer disease: mechanistic and therapeutic considerations

Lancet Neurology, The, 2011
Hyoung-Gon Lee, Antoni Camins, Mercè Pallàs   +2 more
exaly  

The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun

Nature Medicine, 2012
Prabhakaran Vasudevan, Gene Kim, Sadhana A Samant   +2 more
exaly  

2-APQC, a small-molecule activator of Sirtuin-3 (SIRT3), alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis

Signal Transduction and Targeted Therapy
Leilei Fu, Bo Han, Liang Ouyang
exaly  

Sirtuin deacetylases in neurodegenerative diseases of aging

Cell Research, 2013
exaly  

Nutrition, Aging, and Sirtuin 1

2013
openaire   +1 more source

NAD-Dependent Deacetylase Sirtuin-1

2017
openaire   +1 more source