Results 71 to 80 of about 22,194 (215)

In vitro cytotoxic and genotoxic effects of newly synthesised boron ionic liquids

open access: yesBiotechnology & Biotechnological Equipment, 2019
In this study, new molecules containing boron were added to the family of ionic organic compounds, in particular, ionic liquids with a cationic center. This study aimed to determine the cytotoxic and genetic effects of a total of four newly synthesised ...
Sibel Bayil Oguzkan   +4 more
doaj   +1 more source

Meiosis‐specific protein co‐expression in Arabidopsis thaliana: a protein delivery tool in meiotic cells

open access: yesThe Plant Journal, Volume 125, Issue 6, March 2026.
SUMMARY Meiosis is a key process in sexual reproduction, orchestrated by numerous proteins that differ in their spatiotemporal expression level and dynamics. Employing meiotic gene promoters typically leads to varying levels of transgene expression within meiotic and non‐meiotic cells in plants.
Ewa W. Piskorz   +3 more
wiley   +1 more source

How to halve ploidy : lessons from budding yeast meiosis [PDF]

open access: yes, 2012
Maintenance of ploidy in sexually reproducing organisms requires a specialized form of cell division called meiosis that generates genetically diverse haploid gametes from diploid germ cells.
Arumugam, Prakash   +2 more
core   +1 more source

Disrupting Lipid Raft Microdomains to Block Polyploid Giant Cancer Cell Budding and Enhance Radiotherapy Response

open access: yesAdvanced Science, Volume 13, Issue 9, 13 February 2026.
Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng   +20 more
wiley   +1 more source

Investigation of In-ovo cytogenetic effect of Levofloxacin

open access: yesThe Iraqi Journal of Veterinary Medicine, 2018
This study was carried out to investigate the cytogenetic effect of Levofloxacin after In-ovo inoculation. Forty eight fertilized eggs were used, divided equally into eight groups and inoculated through shell puncture above air cell with materials in ...
Marwa H. N.
doaj   +1 more source

The Sister-Chromatid Exchange and Acetylcholine Esterase Enzyme Levels among Patients with Insecticide Intoxication in the Cukurova Region, Turkey. [PDF]

open access: yes, 2006
This study included 45 patients with intentional insecticide intoxication and 21 with accidental intoxication who were treated at the First-Aid and Emergency Department of Balcali Hospital at the Faculty of Medicine in the Cukurova University, Adana ...
Alptekin, Davut   +8 more
core   +1 more source

Non‐Coding RNAs in Breast Cancer Radioresistance: Mechanisms, Functional Roles and Translational Potentials

open access: yesCell Proliferation, Volume 59, Issue 2, February 2026.
Non‐coding RNAs (ncRNAs) regulate breast cancer radioresistance via cell cycle, DNA repair and tumour microenvironment pathways. Targeting ncRNAs (e.g., HOTAIR and miR‐155) with RNA‐based therapies (ASOs and CRISPR) shows promise but faces delivery challenges.
Xiaohui Zhao   +8 more
wiley   +1 more source

Terminalia catappa, an anticlastogenic agent against MMS induced genotoxicity in the human lymphocyte culture and in bone marrow cells of Albino mice

open access: yesEgyptian Journal of Medical Human Genetics, 2014
Background: Terminalia catappa has been used as a folk medicine for treating dermatitis, hepatitis as well as other diseases in India. It possesses anticancer, antioxidant as well as anticlastogenic characteristics.
Mohammad Sultan Ahmad   +4 more
doaj   +1 more source

Permitted daily exposure for diisopropyl ether as a residual solvent in pharmaceuticals [PDF]

open access: yes, 2018
Solvents can be used in the manufacture of medicinal products provided their residual levels in the final product comply with the acceptable limits based on safety data.
Evandri, Maria Grazia, Romanelli, Luca
core   +1 more source

Loss of E3 ligase HvST1 function substantially increases distal crossover frequency

open access: yesNew Phytologist, Volume 249, Issue 3, Page 1325-1341, February 2026.
Summary This study characterizes the function of a grass‐specific E3 ubiquitin ligase, HvST1, in regulating synapsis and crossover (CO) formation during meiosis in barley (Hordeum vulgare). In large‐genome cereals, COs are predominantly restricted to distal chromosomal regions, limiting genetic recombination and breeding flexibility.
Jamie Neil Orr   +8 more
wiley   +1 more source

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