Investigation of gadobutrol-induced Sister Chromatid Exchange in G0 phase and circulating human lymphocytes [PDF]
Arhiv za farmacijuGadobutrol (Gadovist®) is a macrocyclic, extracellular gadolinium-based contrast agent widely used in magnetic resonance imaging. This study aims to assess the genotoxic and cytotoxic potential of gadobutrol in human G0 phase lymphocytes and circulating ...
Cobanoglu Hayal, Cayir Akin
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Ultrastructural analysis of chromatin in meiosis I plus II of rye (Secale cereale L.) [PDF]
, 2004 Scanning electron microscopy (SEM) proves to be an appropriate technique for imaging chromatin organization in meiosis I and II of rye (Secale cereale) down to a resolution of a few nanometers.
Herrmann, Reinhold G. +3 more
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MedComm, Volume 6, Issue 12, December 2025.Radiation‐induced biological effects are an extremely complex and extensive mechanism that involves multiple aspects of physiological activities in organisms. In the medical field, utilizing the damaging effects of radiation to treat tumors is a commonly employed therapeutic approach.
Zhihe Hu +5 more
wiley +1 more source
Analysis of the impact of the absence of RAD51 strand exchange activity in Arabidopsis meiosis.
PLoS ONE, 2017 The ploidy of eukaryote gametes must be halved to avoid doubling of numbers of chromosomes with each generation and this is carried out by meiosis, a specialized cell division in which a single chromosomal replication phase is followed by two successive ...
Gunjita Singh +3 more
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Laser-UV-microirradiation of interphase nuclei and posttreatment with caffeine: a new approach to establish the arrangement of interphase chromosomes [PDF]
, 1976 Laser UV microirradiation of Chinese hamster interphase cells combined with caffeine post-treatment produced different patterns of chromosome damage in mitosis following irradiation of a small area of the nucleus that may be classified in three ...
B. A. Kihlman +19 more
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Rad51 at the Crossroads: Bridging DNA Repair, Tumorigenesis, and Immune Regulation
Med Research, Volume 1, Issue 3, Page 359-377, December 2025.Therapeutic landscape of Rad51 in cancer treatment. Key elements include (1) DNA damage sources (PARPi, chemo/radiotherapy); (2) repair pathways (Rad51‐mediated HR); (3) intervention strategies (Rad51 inhibitors, CRISPR/Cas9); and (4) combination approaches (immunotherapy). The figure is created with BioRender.com.
Zhendong Qin +4 more
wiley +1 more source
Resolving RAD51C function in late stages of homologous recombination
Cell Division, 2007 DNA double strand breaks are efficiently repaired by homologous recombination. One of the last steps of this process is resolution of Holliday junctions that are formed at the sites of genetic exchange between homologous DNA.
Kuznetsov Sergey G, Sharan Shyam K
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Permitted daily exposure for diisopropyl ether as a residual solvent in pharmaceuticals [PDF]
, 2018 Solvents can be used in the manufacture of medicinal products provided their residual levels in the final product comply with the acceptable limits based on safety data.
Evandri, Maria Grazia, Romanelli, Luca
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Safety evaluation of jagua (genipin‐glycine) blue as a food additive
EFSA Journal, Volume 23, Issue 12, December 2025.Abstract The EFSA Panel on Food Additives and Flavourings (FAF Panel) provides a scientific opinion on the safety of jagua (genipin‐glycine) blue as a new food additive. Jagua (genipin‐glycine) blue is obtained by water extraction of the ground pulp of the peeled, unripe fruits of Genipa americana L.
EFSA Panel on Food Additives and Flavourings (FAF) +29 more
wiley +1 more source
Molecular mechanism in a rare autosomal recessive case of xeroderma pigmentosum - a case report
National Journal of Clinical Anatomy, 2014 Chromosomal instability syndromes are a special group of disorders of cytogenetic interest which comprises of several rare, autosomal recessive conditions.
Vijaya Ramanathan, Anand Ramanathan
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